Wise Lab Presentations

2020-Present|2010-2019|2000-2009|1990-1999

Wise Laboratory Presentations

2020-Present

Wise, J.T.F., Chiarugi, D., Gu, H., and Wise, Sr., J.P. A Whale of a Tale: One Environmental Health to Study the Impacts of Hexavalent Chromium Exposure on Human and Whale Lung Metabolomes. Presented at the Biennial Meeting of PRIMO (Pollution Research in Marine Organisms), Nantes, France, May 2024.

Lu, H., Meaza I., Williams, A., Browning, C., Wise, S.S., Speer, R.M., and Wise, Sr., J.P. Of Whales and Men, Translating How Chromosome Instability Drives Environmental Lung Carcinogenesis across Species and Biological Levels of Organization. Presented at the International Forum on Toxicology and Pharmacology (TOXIFORUM 2024), Munich, Germany, April 2024.

Meaza I., Toyoda, J.H., Williams, A., Lu, H., Wise, S.S., Kouokam. J.C., Croom-Perez, T.J., and Wise, Sr., J.P. Prolonged Hexavalent Chromium Exposure Induces Loss of Homologous Recombination Repair and Increases Chromosome Instability. Presented at the International Forum on Toxicology and Pharmacology (TOXIFORUM 2024), Munich, Germany, April 2024.

Williams, A., Meaza I., Lu, H., Toyoda, J.H., Browning, C., Wise, S.S., Kouokam. J.C., and Wise, Sr., J.P. Particulate Hexavalent Chromium Induces DNA Damage Via RAD51D Disruption in Human Lung Cells but Not in Alligator Lung Cells. Presented at the International Forum on Toxicology and Pharmacology (TOXIFORUM 2024), Munich, Germany, April 2024.

Delnicki, M., Guo, L., Wise, Sr., J.P., Wise, Jr., J.P., Young Wise, J. Chromosome Instability: A New “Hit” in Liver Disease. Presented at the International Forum on Toxicology and Pharmacology (TOXIFORUM 2024), Munich, Germany, April 2024.

James, W., Wise, J.T.F., Lu, H., Meaza, I. Wise, S.S., Williams, A.R., Young Wise, J., Xia, B., and Wise, Sr., J.P. Hexavalent Chromium Induces DNA Double Strand Breaks and Inhibits Break Repair in Rodent Lung Cells. Presented at MANRRS (National Society for Minorities in Agriculture, Natural Resources, and Related Sciences) 38th Annual Conference and Training, Chicago, IL, 2024.

Buchanan, L., Vielee, S.T., Roof, S., Lu, H., Young-Wise, J.L., Meaza, I.I., Williams, A., Kouokam, J.C., Guo, L., Speer, R.M., Cai, J., Wise, Sr., J.P., Cai, L., and Wise, Jr., J.P. Low Concentrations of Hexavalent Chromium in Drinking Water Induce Alzheimer’s Disease Neuropathology: Using a Toxic Aging Coin Approach to Assess Hexavalent Chromium Neurotoxicity. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #3151, 2024.

Delnicki, M.E, Guo. L., Meaza, I., Williams, A., Speer, R.M., Kouokam, J.C., Wise, S.S., Wise, Sr., J.P., Wise, Jr., J.P., Vielee, S.T., Bolatimi, O.E., Cave, M.C., Young Wise, J. Impact of Hexavalent Chromium and High-Fat Diet on Liver Disease. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #4728, 2024.

James, W., Wise, J.T.F., Lu, H., Meaza, I. Wise, S.S., Williams, A.R., Young Wise, J., Xia, B., Wise, Sr., J.P. Hexavalent Chromium Induces DNA Double Strand Breaks and Inhibits Break Repair in Rodent Lung Cells. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #4736, 2024

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M., Croom-Perez, T.J., Meaza I., Williams, A., Wise, Jr., J.P. Kouokam. J.C., Young Wise, J.L., Cai, L., Zhu, C., Kondo, K., and Wise, Sr., J.P. Particulate Hexavalent Chromium Exposure Induces DNA Damage and Disturbs Homologous Recombination Repair in Lung Tissue. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #3238, 2024.

Meaza I., Speer M.R., Kouokam J.C., and Wise, Sr., J.P. Particulate Hexavalent Chromium Targets the Expression of Genes Involved in Lung Cancer and DNA Repair Pathways in Human Lung Cells. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #2005, 2024.

Williams, A., Meaza I., Lu, H., Toyoda, J.H., Browning, C., Wise, S.S., Kouokam. J.C., and Wise, Sr., J.P. Inhibition of RAD51D of the BCDX2 Complex Is a Key Driver of Hexavalent Chromium Induced Suppression of RAD51. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #4742, 2024.

Wise, J.T.F., Chiarugi, D., Gu, H., and Wise, Sr., J.P. Hexavalent Chromium Exposure Impacts the Metabolome of Human Lung Fibroblast Cells. The Toxicologist, a Supplement to Toxicological Sciences, Abstract # 4737, 2024.

Wise, S.S., Wise, J.T.F., Meaza, I., Lu, H., and Wise, Sr., J.P. Telomerase-mediated Lifespan Extension in Whale Cells Provides a New Model for Chemical Carcinogenesis. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #4713, 2024.

Vielee, S.T., Meaza I., Buchanan, L., Roof, S., Lu, H., Guo, L., Wise, S.S., Easley, J., Kouokam, J.C., Young Wise, J., Williams, A.R., Wise, Sr., J.P., Cai, J., Wise, Jr., J.P. Hexavalent Chromium Induces Behavioral Neurotoxicity in a Guinea Pig Model: A New Model for Cr(VI) Neurotoxicity. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #3152, 2024.

Vielee, S. T., Lu, J., Young Wise, J., Meaza, I. I., Williams, A., Kouokam, J. C., Wise, S. S., Lin, Q., Toyoda, J. H., Guo, L., Speer, R. M., Cai, J., Rane, M., LeBlanc, A., Cave, M., Wise, Sr., J.P., Cai, L., and Wise, J. P., Jr. Using a Toxic Aging Coin to Address Concerns for the Global Aging Crisis: Heads for Age Differences, Tails for Accelerated Aging. Annual meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Louisville, Kentucky, November 2023.

Lu, H., Wise, S.S., Toyoda, J.H., Speer, R.M., and Wise, Sr., J.P. Homologous Recombination Repair Protect Whale Cells to Avoid Cr(VI)-Induced Chromosome Instability. Annual meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Louisville, Kentucky, November 2023.

Meaza I., Speer M.R., Kouokam J.C., and Wise, Sr., J.P. Particulate Hexavalent Chromium Targets Genes in Lung Cancer and DNA Repair Pathways. Annual meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Louisville, Kentucky, November 2023.

Williams, A., Meaza I., Lu, H., Wise, S.S., Browning, C., Toyoda, J.H., Kouokam. J.C., and Wise, Sr., J.P. Particulate Hexavalent Chromium Induces DNA Damage Response Failure in Human Cells but Not in Alligator Cells. Annual meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Louisville, Kentucky, November 2023.

Tariq, Z., Calhoon, D., Wise, Sr., J.P., Lechner, J., and Kouokam, J.C. Beetroot Extract Reduces the Cell Killing and Pro-Inflammatory effects of Hexavalent Chromium. Presented at Research Louisville!, October 2023.

Wise, J.P., Jr., Vielee, S.T., Roof, S., Buchanan, L, Lu, H., Wise, S. S., Meaza, I. I., Williams, A., Young Wise, J., Wise, Sr., J.P., Cai, J., Cai, L., and Speer, R. M. Hexavalent chromium (Cr[VI]) induced behavioral effects and neurodegeneration in rats after 90 days drinking water exposure. Presented at the annual meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), October 2023.

Meaza I. Speer M.R., Kouokam J.C., and Wise, Sr., J.P. Particulate Hexavalent Chromium Targets Genes in Lung Cancer and DNA Repair Pathways. Presented at the annual meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), October 2023.

Young, J.L., Bolatimi, O.E., Cave, M.C., Wise, Sr., J.P., Wise, Jr., J.P. Chromosome Instability: a New “Hit” in Liver Disease. Presented at the 3rd Chromosomal Instability as a Driver of Human Disease Conference, Croatia, October 2023.

Lu, H., Browning, C. L., Wise, S.S., Speer, R.M., Liu. K.J. and Wise, Sr., J.P. From Cells to Tumors, Translating How Chromosome Instability Drives Environmental Carcinogenesis across Species and Biological Levels of Organization. Presented at the 3rd Chromosomal Instability as a Driver of Human Disease Conference, Croatia, October 2023.

Wise, Jr., J.P., Vielee, S.T., Cave, M., Young Wise, J., Kouokam, J.C., Wise, S.S., Lin, Q, Toyoda, J.H., Lu, H., Meaza, I.I., Williams, A.R., Rane, M., LeBlanc, A., Guo, L. Speer. R.M., Cai, Wise, Sr., J.P., and Cai, L. A Toxic Aging Coin: Investigating the Intersection of Aging and Toxicology of Hexavalent Chromium (Cr[VI]) in the Brain. Presented at the Gordon Research Conference: Cell Biology of Metals in West Dover, VT. July-August 2023.

Roof, S. Vielee, S. T., Buchanan, L., Lu, H., Young Wise, J., Meaza, I. I., Williams, A. R., Guo, L., Kouokam, J. C., Wise, S., Cave, M., LeBlanc, A. J., Rane, M., Speer, R., Wise, Sr., J. P., Cai, L., Cai, J., and Wise, Jr., J. P. Using a Toxic Aging Coin to Rethink Drinking Water Safety for Hexavalent Chromium. Presented at the 22nd Annual Posters at the Capital. July 2023.

Roof, S. H., Vielee, S. T., Lu, H., Young-Wise, J., Meaza, I. I., Williams, A., Kouokam, J. C., Wise, S. S., Guo, L., Speer, R. M., Cai, J., Wise, Sr., J.P., Cai, L. and Wise, Jr., J.P. Using a Toxic Aging Coin Approach: Evidence for Cr(VI) Exposure Contributing to Parkinson’s Disease. Presented at the Ohio Valley Society of Toxicology Summer Trainee Meeting, July 2023.

Buchanan, L., Vielee, S. T., Lu, H., Young-Wise, J., Meaza, I. I., Williams, A., Kouokam, J. C., Wise, S. S., Guo, L., Speer, R. M., Cai, J., Wise, Sr., J.P., Cai, L. and Wise, Jr., J.P. Using A Toxic Aging Coin Approach: Does Exposure to Low Concentrations of Cr(VI) Affect Alzheimer’s Disease Neuropathology? Presented at the Ohio Valley Society of Toxicology Summer Trainee Meeting, July 2023.

Vielee, S. T., Lu, H., Young-Wise, J., Meaza, I., Williams, A., Kouokam, J. C., Wise, S., Guo, L., Cai, J., Wise, Sr., J.P., Cai, L. and Wise, Jr., J.P. Hexavalent Chromium Accumulates in the Rat Brain and Alters Behavior Distinctly Across the Lifespan: A Toxic Aging Coin Approach to Cr(VI) Neurotoxicity. Presented at the Ohio Valley Society of Toxicology Summer Trainee Meeting, July 2023.

Meaza I., Toyoda H. J., Kouokam J. C., Cahill C.C. and Wise J.P. Sr. Metal-Induced Cohesin Dysregulation Is a Key Step in the Development of Chromosome Instability. Presented at the Ohio Valley Society of Toxicology Summer Meeting, 2023.

Wise, Jr., J., Vielee, S.T., Lu, H., Meaza, I., Williams, A., Young Wise, J., Kouokam, C.J., Wise, S.S., Rane, M., LeBlanc, A., Cave, M., Lin, Q., Toyoda, J.H., Guo, L., Cai, J., Wise, Sr., J.P., Cai, L., Speer, R.M. Using A Toxic Aging Coin for Cr(VI) Neurotoxicity: Investigating the Intersection of Aging and Toxicology of Hexavalent Chromium in the Brain. Presented at the 18th International Neurotoxicology Association (INA), Durham, North Carolina, May 2023.

Wise, Sr., J.P., Lu, H. and Wise, S.S. From Cells to Tumors, Translating the Carcinogenic Mechanism for Hexavalent Chromium across Species and Biological Levels of Organization. Proceedings of the 8th Georgian Bay International Conference on Bioinorganic Chemistry, Parry Sound, Ontario, Canada, May 2023.

Williams, A. R., Speer, R.M., Browning, C. L., Meaza, I., Toyoda, J.H., Lu, H., Wise, S.S., Kouokam, J.C., and Wise, Sr., J.P. DNA Repair Protein Response to Hexavalent Chromium in Alligator and Human Lung Cells. Presented at the Annual Meeting of the Genetic and Toxicology Association (GTA) meeting, May 2023.

Kouokam, J.C., Speer, R.M., Meaza, I., Toyoda, J.H., Lu, H. and Wise, Sr., J.P. Particulate hexavalent chromium increases reactive oxygen species production and regulates multiple inflammatory pathways in human lung fibroblasts. The Toxicologist, a Supplement to Toxicological Sciences, Abstract # 3603, 2023.

Vielee, S.T., Williams, A.R., Lu, H., Meaza, I.I., Toyoda, J.H., Wise, Sr., J.P., and Wise, Jr., J.P. A Toxic Aging Coin: An Assessment of Cr(VI)-Induced Biological Aging in the Brain. The Toxicologist, a Supplement to Toxicological Sciences, Abstract # 4577, 2023.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M., Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young, J.L., Cai, L., Zhu, C., Kondo, K., Zheng, T., Haber, L.T., Jia, G., and Wise, Sr., J.P. Translating Particulate Hexavalent Chromium-Induced DNA Damage and DNA Repair Impacts from Human Lung Cells to Lung Tissue. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #3380, 2023.

Williams, A. R.,  Speer, R.M., Browning, C. L., Meaza, I., Toyoda, J.H.,   Lu, H., Wise, S.S., Kouokam, J.C., and Wise, Sr., J.P. Hexavalent Chromium [Cr(VI)] Induces Homologous Recombination Repair Failure in Human Cells but Not in Alligator Cells. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #3392, 2023.

Meaza I., Toyoda H. J., Kouokam J. C., Cahill C.C. and Wise, Sr., J.P. Hexavalent Chromium-Induced Cohesin Malfunction Drives Chromosome Instability, a Key Step in the Mechanism of Carcinogenesis. The Toxicologist, a Supplement to Toxicological Sciences, Abstract #3597, 2023.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M., Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young, J.L., Cai, L., Zhu, C., Kondo, K., Zheng, T., Haber, L.T., Jia, G., and Wise, Sr., J.P. Hexavalent Chromium [Cr(VI)] Targets Rad51 to Drive Carcinogenesis in Lung Cancer. Presented at the 62nd Annual Meeting of the Society of Toxicology, Nashville, Tennessee, 2023.

Hamilton, M., Patel, R., Lechner J., Wise, Sr., J.P., and Kouokam, J.C. Betanin, a Beetroot-derived Food Colorant, Decreases Cr(VI)-induced Toxicity in Human Lung Epithelial Cells. Presented at KY Academy of Sciences, Morehead State University, November 2022.

Meaza I., Toyoda H. J., Kouokam C. J., Cahill C.C., and Wise J.P. Sr., Cohesin Malfunction, a New Mechanism for Hexavalent Chromium-Induced Carcinogenesis. Presented at the Annual Meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Pittsburgh, Pennsylvania, 2022.

Wise, Sr., J.P. Wise, Jr., J.P., Wise, S.S., Young, J.L., Wise, J.T.F., Wise, C.F., Browning, C.L., Perkins, C.R., Kerr, I., and  Zheng, T. Of Whales and Men:  A Multi-Year Study of Metals in Whales from the Gulf of Maine. Presented at the Annual Meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Pittsburgh, Pennsylvania, 2022.

Wise, Jr., J.P., Vielee, S., Isibor, J., Williams, A.R., Meaza, I.I., Toyoda, J.H., Wise, S.S., Kouokam, J.C., Young, J.L., Wise, Sr., J.P., Cai, J. and Cai L. A Toxic Aging Coin: Case for Cr(VI) Neurotoxicity and Gerontogenicity. Presented at the 11th Conference on Metal Toxicity and Carcinogenesis, Montreal, Quebec Canada, October 2022

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M., Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young, J.L., Cai, L., Zhu, C., Kondo, K., Zheng, T., Haber, L.T. and Wise, Sr., J.P. The Carcinogenic Mechanism for Particulate Hexavalent Chromium Translates from Cultured Human Lung Cells to In Vivo Lung Tissue. Presented at the 11th Conference on Metal Toxicity and Carcinogenesis, Montreal, Quebec Canada, October 2022.

Young, J.L.,  Bolatimi, O.E., Toyoda, J.H., Lu, H., Meaza, I., Williams, A.R., Wise, S.S., Kouokam, J.C., Lin, Q., Wise, Sr. J.P., Wise, Jr., J.P., Cai, L., and Cave, M.C. Environmental Liver Disease and YOU: How Sex, Diet and Metals Interact. Presented at the 11th Conference on Metal Toxicity and Carcinogenesis, Montreal, Quebec Canada, October 2022.

Meaza I., Cahill C.C. and Wise Sr., J.P. The Unloading of Cohesin from Chromatin a New Mechanism for Hexavalent Chromium-Induced Carcinogenesis. Presented at the Annual Ohio Valley Chapter of Society of Toxicology (OVSOT) Meeting, October, 2022.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M, Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young, J.L, Cai, L., Zhu, C., Kondo, K., Zheng, T., Haber, L.T., and Wise, Sr., J.P. Translating Particulate Hexavalent Chromium-Induced Genotoxic and DNA Repair Impacts from Human Lung Cells to In Vivo Lung Tissue. Presented at the Ohio Valley Society of Toxicology (OVSOT) Meeting, October 2022.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., Wise, S., Kouokam, J.C., and Wise, Sr., J.P. Particulate Hexavalent Chromium Exposure Induces RAD51D Loss Leading to Impaired Function with Each Successive Generation in Human Lung Cells. Presented at the Ohio Valley Society of Toxicology (OVSOT) Meeting, October 2022.

Vielee, S.T., Williams, A.R., Meaza, I., Toyoda, J.H., Wise, Sr., J.P. and Wise, Jr., J.P. A Mechanistic Approach to Categorizing Cr(VI) as a Gerontogen Using a Toxic Aging Coin. Presented at the Ohio Valley Society of Toxicology (OVSOT) Meeting, October 2022.

Wise, Jr., J.P., Vielee, S.T., Williams, A.R., Meaza, I., Toyoda, J.H., Wise, S.S., Kouokam, J.C., Young, J.L., Wise, Sr., J.P., Cai, J., Cai, L. A Toxic Aging Coin: Case for Cr(VI) Neurotoxicity and Gerontogenicity. Environmental and Molecular Mutagenesis, 63 (S1): 41, 2022.

Vielee, S.T., Williams, A.R., Meaza, I., Toyoda, J.H., Wise, Sr., J.P. and Wise, Jr., J.P. Evidence to Classify Cr(VI) as a Gerontogen: A Mechanistic Approach to Making Heads or Tails of a Toxic Aging Coin. Environmental and Molecular Mutagenesis, 63 (S1): 41, 2022.

Toyoda, J.H., Meaza, I., Lu. H., Kouokam, J.C., Williams, A.R., and Wise, Sr., J.P. Hexavalent Chromium Targets Securin and Causes Numerical Chromosome Instability in Human Cells but Not in Whale Cells. Environmental and Molecular Mutagenesis, 63 (S1): 143, 2022.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., Wise, S.S., Kouokam, C.J., and Wise, Sr., J.P. Particulate Hexavalent Chromium Inhibits RAD51 Paralog complex (BCDX2) Response in Human Lung Cells. Environmental and Molecular Mutagenesis, 63 (S1): 105, 2022.

Meaza, I., Toyoda, J.H., Lu. H., Williams, A.R., Kouokam, J.C., and Wise, Sr., J.P. Prolonged Exposure to Particulate Hexavalent Chromium Induces Inhibition of RAD51 and Increased Chromosome Instability in Human Bronchial Epithelial Cells. Environmental and Molecular Mutagenesis, 63 (S1): 47, 2022.

Patel, R., Hamilton, M., Lechner J., Wise, Sr., J.P. and Kouokam, J.C. Beetroot-derived E162 Alleviates Hexavalent Chromium-induced Toxicity in Human Lung Epithelial Cells. Presented at Research!Louisville, September 2022.

Duncan, A., Oyeleye, S., Wise, Sr., J.P. and Kouokam, J.C. Betanin, a Beetroot-derived Food Colorant, Decreases Cr(VI)-induced Toxicity in Human Lung Fibroblasts by Relieving Oxidative Stress. Presented at Research!Louisville, September 2022.

Oyeleye, S., Duncan, A., Lechner J., Wise, Sr., J.P. and Kouokam, J.C. Could E162 Prevent Hexavalent Chromium-induced Cancer? A Study of Human Lung Fibroblasts. Presented at Research!Louisville, September 2022.

Vielee, S.T., Williams, A.R., Meaza, I., Toyoda, J.H.  Wise, Sr., J.P. and Wise, Jr., J.P. The Tale of Heavy Metals in Aging: Cr(VI) Induces Senescence in DNA Damage Repair Deficient Cells. Presented at Research!Louisville, September 2022.

Cahill C.C, Meaza I. and Wise J.P. Sr. Mechanism of Hexavalent Chromium Carcinogenesis: The Unloading of Cohesin from Chromatin.  Presented at Research Louisville! October 2022.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., Wise, S., Kouokam, J.C., and Wise, Sr., J.P. Particulate Hexavalent Chromium Exposure Inhibits RAD51 Paralog Complex (BCDX2) Response in Human Lung Cells. Presented at Research Louisville! October 2022.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M, Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young, J., Olapeju, E., Cai, L., Kondo, K., and Wise, Sr., J.P. Translating Particulate Hexavalent Chromium-Induced DNA Damage and DNA Repair Impacts from Cultured Human Lung Cells to In Vivo Lung Tissue. Presented at Research Louisville! October 2022.

Fernando, J. Williams, A.R., Wise, S.S., and Wise, Sr., J.P. Carcinogenic Chromium Disrupts RAD51 and RAD51D Function in Homologous Recombination in Human Lung Cells. Presented at Research Louisville! October 2022.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., Wise, S., Kouokam, J.C., and Wise, Sr., J.P. Hexavalent Chromium Inhibits RAD51 Function through Impaired RAD51D. Presented at the Ohio Valley Society of Toxicology Summer Meeting, 2022.

Vielee, S.T., Williams, A.R., Meaza, I., Toyoda, J.H., Isibor, J., Wise, Sr., J.P. and Wise, Jr., J.P.. Aging at the flip of a coin: A mechanistic approach to describing the gerontogenic effects of Cr(VI). Presented at the Ohio Valley Society of Toxicology Summer Meeting, 2022.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M, Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young J.L., Cai, L., Zhu, C., Kondo, K., Zheng, T., Haber, L.T., and Wise, Sr., J.P. Environmental Carcinogenesis in the Gulf Coast and Southern States: Translating the Genotoxic and DNA Repair Impacts of Particulate Hexavalent Chromium from Cultured Human Lung Cells to In Vivo Lung Tissue. Presented at the Second Meeting of the Southern Genome Maintenance Conference, Miami, Florida, June 2022.

Meaza, I., Toyoda, J.H., Lu. H., Williams, A.R., Kouokam, J.C., and Wise, Sr., J.P. Prolonged Chromate Exposure Causes Inhibition of RAD51 Response and Increases Chromosome Instability in Human Bronchial Epithelial Cells. Presented at the Biennial Meeting of the International Conference of Trace Elements and Minerals, Aachen, Germany, June 2022.

Toyoda, J.H., Wise, S.S., Liu, K-J., Holmes, A.L., Martino, J., The Mechanisms of Chromium Carcinogenesis: A One Environmental Health Perspective. Presented at the Biennial Meeting of the International Conference of Trace Elements and Minerals, Aachen, Germany, June 2022.

Meaza, I., Toyoda, J.H., Lu. H., Williams, A.R., Kouokam, J.C., and Wise, Sr., J.P. Particulate Hexavalent Chromium Causes DNA Double Strand Breaks and RAD51 Inhibition. Leading to Increased Chromosome Instability in Human Bronchial Epithelial Cells. Presented at the Genetic Toxicology Association, Virtual Meeting, May 2022.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M, Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young J.L., Cai, L., Kondo, K., and Wise, Sr., J.P. Subchronic Particulate Hexavalent Chromium Exposure Inhibits Homologous Recombination Repair in Rat Lung. Presented at the Graduate Student Regional Research Conference, Louisville, Kentucky, March 2022.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., Wise, S.S., Kouokam, C.J., and Wise, Sr., J.P. Particulate Hexavalent Chromium Inhibits DNA Repair by Targeting the BCDX2 Complex in Human Lung Cells. Presented at the 15th Annual Graduate Student Regional Research Conference (GSC), March 2022.

Meaza, I., Toyoda, J.H., Lu. H., Williams, A.R., Kouokam, J.C., and Wise, Sr., J.P. Prolonged Chromate Exposure Causes Inhibition of RAD51 Response and Increases Chromosome Instability in Human Bronchial Epithelial Cells. Presented at the 15th Annual Graduate Student Regional Research Conference (GSC), March 2022.

Meaza, I., Toyoda, J.H., Lu. H., Williams, A.R., Kouokam, J.C., and Wise, Sr., J.P. Missing Protein! Have You Seen it? Reward: to Cure Cancer. Presented at the Annual Meeting of the Society of Toxicology (SOT), March 2022.

Wise, Sr., J.P. and Wise, C.F. All for One and One for All: One Environmental Health in Toxicology. Toxicological Sciences, 186: 1060, 2022.

Flores, M., and Wise, Sr., J.P. Space Toxicology: An Emerging Environmental Health Field. Toxicological Sciences, 186: 3602, 2022.

Wise, S.S., Toyoda, J.H., Lu, H., Meaza, I., Wise, Sr., J.P. Chromosome Instability and Cellular Transformation of Human Lung Cells Chronically Treated with Particulate Hexavalent Chromium. Toxicological Sciences, 186: 3261, 2022.

Wise, Jr., J.P., Young, J.L., Lu, H., Meaza, I.I., Toyoda, J., Wise, S.S., Speer, R., Croom-Perez, T., Cai, L., and Wise, Sr., J.P. A Toxic Aging Coin: Cr(VI) Neurotoxicity and Gerontogenicity. Toxicological Sciences, 186: 3771, 2022.

Toyoda, J.H., Speer, R.M., Meaza, I., Lu, H., Kouokam, J.C., Williams, A.R., and Wise, Sr., J.P. Hexavalent Chromium Induces Numerical Chromosome Instability Via Securin Disruption in Human Cells but Not in Whale Cells. Toxicological Sciences, 186: 3174, 2022.

Lu, H., Wise, S.S., Toyoda, J.H., Wise Jr. J.P., Speer, R.M, Bolt, A.M., Meaza, I., Wise, C.F., Wise, J.T.F., Young, J.L., and Wise Sr. J.P. Of Whales and Men, How Great Whales Evade Metal Induced Cancer. Toxicological Sciences, 186: 1064, 2022.

Meaza I., Toyoda, J.H., Lu, H., Williams, A.R., and Wise Sr. J.P. Chromate-Induced Loss of RAD51 and Increased Chromosome Instability in Human Bronchial Epithelial Cells. Toxicological Sciences, 186: 3135, 2022.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M, Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young J.L., Cai, L., Kondo, K., and Wise, Sr., J.P. Particulate Hexavalent Chromium Inhibits Homologous Recombination Repair in Rat Lung Tissue. Toxicological Sciences, 186: 3732, 2022.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., and Wise, Sr., J.P. Particulate Hexavalent Chromium Exposure Suppresses BCDX2 Complex Response in Human Lung Cells. Toxicological Sciences, 186: 3734, 2022.

Kouokam, J.C., Speer, R.M., Meaza, I., Toyoda, J.H., Lu, H., Kong, M. and Wise, Sr., J.P. Analysis of the effects of particulate hexavalent chromium on global gene expression in human fibroblasts reveal the involvement of inflammation. Toxicological Sciences, 186: 3735, 2022.

Toyoda, J.H., Cahill, C.R., Wise, S.S., Speer, R.M., Lu, H., Kouokam, J.C., and Wise, Sr., J.P. Securin Disruption and Chromosome Instability Persist After Chronic Hexavalent Chromium Exposure. Presented at the annual meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), November 2021.

Meaza I., Toyoda, J.H., Lu, H., Williams, A.R., and Wise Sr. J.P. Particulate Hexavalent Chromium Causes DNA Repair Inhibition Leading to Increased Chromosome Instability in Human Bronchial Epithelial Cells. Presented at the annual meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), November 2021.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M, Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Young J.L., Cai, L., Kondo, K., and Wise, Sr., J.P. Particulate hexavalent chromium inhibits homologous recombination repair in rat lung. Presented at the annual meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), November 2021.

Williams, A.R., Meaza, I., Toyoda, J., Wise, S.S., Kouokam, J.C., Speer, R.M., Browning, C.L., and Wise, Sr., J.P. Particulate Hexavalent Chromium Induces Loss of the BCDX2 Complex Leading to Loss of Homologous Recombination Repair. Presented at the annual meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), November 2021.

Wise, Jr., J.P., Young, J.L., Lu, H., Meaza, I., Toyoda, J.H., Wise, S.S., Speer, R.M., Croom-Perez, T.J., Cai, L., and Wise, Sr., J.P. A Toxic Aging Coin: Cr(VI) Neurotoxicity and Gerontogenicity. Presented at the annual meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), November 2021.

Toyoda, J.H., Cahill, C.R., Wise, S.S. and Wise, Sr., J.P. Securin Deregulation and Chromosome Instability Persist After Chronic Hexavalent Chromium Exposure. Presented at Research!Louisville, October 2021.

Cahill, C.R., Toyoda, J.H., Wise, S.S. and Wise, Sr., J.P. Securin Deregulation Persists After Chronic Hexavalent Chromium Exposure. Presented at Research!Louisville, October 2021.

Meaza, I., Toyoda, J.H., Lu, H., Williams, A.R., Wise, S.S. and Wise Sr. J.P. Particulate Hexavalent Chromium Targets RAD51, the Key Protein in Homologous Recombination Repair, Leading to Increased Genomic Instability, A Driver of Carcinogenesis at Research Louisville! Presented at Research!Louisville, October 2021.

Hoang, L., Meaza I. and Wise Sr. J.P. Particulate Cr(VI) Targets Separase in Human Lung Cells. Presented at Research!Louisville, October 2021.

Williams, A., Meaza, I., Toyoda, J.H., Speer, R.M. Browning, C.L. and Wise, Sr., J.P. Particulate Hexavalent Chromium Targets the BCDX2 Complex in Homologous Recombination Repair. Presented at Research!Louisville, October 2021.

Lu, H., Wise, S.S., Hoyle, G., Toyoda, J.H., Speer, R.M, Croom-Perez, T.J., Meaza, I., Wise, Jr., J.P., Kouokam, J.C., Cai, L.  and Wise, Sr., J.P. Particulate hexavalent chromium induces DNA double strand breaks in rat lung. Presented at Research!Louisville, October 2021.

Kouokam, J.C., Speer R. M., Meaza I., Toyoda J. H., Lu H., Kong M. and Wise, Sr, J.P. Particulate hexavalent chromium-induced toxicity involves the inflammatory response in human lung fibroblasts. Presented at the Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS), 2021.

Lu, H., Wise, S.S., Toyoda, J.H., Speer, R.M, Bolt, A., and Wise, Sr., J.P. A Whale of a Tale: Whale Lung Cells Resist Particulate Cr(VI)-Induced Chromosome Instability. Environmental and Molecular Mutagenesis Volume 62, Issue S1, p.63-64, 2021.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., and Wise, Sr., J.P. Particulate Hexavalent Chromium Targets RAD51 Paralogs Leading to Loss of Homologous Recombination Repair in Metal Carcinogenesis. Environmental and Molecular Mutagenesis Volume 62, Issue S1, p.63, 2021.

Meaza, I., Toyoda, J.H., Lu, H., Williams, A.R., Wise, S.S., and Wise Sr. J.P. Particulate Hexavalent Chromium Induces Loss of RAD51 Leading to Increased Genomic Instability, A Driver of Carcinogenesis. Environmental and Molecular Mutagenesis Volume 62, Issue S1, p57, 2021.

Toyoda, J.H., Cahill, C.R., Wise, S.S., and Wise, Sr., J.P. Chronic Hexavalent Chromium Exposure Causes Persistent Securin Disruption, and Induces Chromosome Instability. Environmental and Molecular Mutagenesis Volume 62, Issue S1, p.44, 2021.

Doyle, C., Williams, A.W., Browning, C.L., Wise, S. and Wise, Sr., J.P. Particulate Hexavalent Chromium Exposure Induces Persistent and Heritable Loss of RAD51D. Presented at Research!Louisville, July 2021.

Brian, E., Temgoua, L., Lechner J., Wise, S. Wise, Sr., J.P. and Kouokam, J.C. Effects of Beetroot-Derived E162 on Cr(VI)-Induced Cytotoxicity. Presented at Research!Louisville, July 2021.

Meaza, I., Speer, R.M., Toyoda, J.H., Lu, Y., Xu, Q., Walter, R., Kong, M. and Wise, Sr., J.P.  Particulate Hexavalent Chromium [Cr(VI)] Exposure Alters miRNA Profiles and Targets miRNAs Involved in Pathways of Cr(VI) Carcinogenesis. Presented at the summer meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), July 2021

Lu, H., Wise, S.S., Toyoda, J.H., Speer, R.M, Bolt, A., and Wise, Sr., J.P. Whale cells are resistant to Cr(VI)-induced chromosome instability. Presented at the annual meeting of the Genetic Toxicology Association, May 2021.

Meaza, I., Speer, R.M., Toyoda, J.H., Lu, Y., Xu, Q., Walter, R., Kong, M. and Wis​e, Sr., J.P. Particulate Hexavalent Chromium Induces Global miRNA Downregulation and Altered the Expression of miRNAs Involved in Carcinogenesis Pathways. Presented at the annual meeting of the Genetic Toxicology Association, May 2021.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., and Wise, Sr., J.P. Particulate Hexavalent Chromium Inhibits RAD51 Paralog Proteins-Key to Lung Cancer Progression. Presented at the annual meeting of the Genetic Toxicology Association, May 2021.

Toyoda, J.H., Martino, J., Speer, R.M., Wise, S.S., and Wise, Sr., J.P. Particulate Hexavalent Chromium Targets Securin, Disrupts Centriole Engagement, and Induces Chromosome Instability. Presented at the annual meeting of the Genetic Toxicology Association, May 2021.

Toyoda, J.H., Martino, J., Speer, R.M., Wise, S.S, and Wise, Sr., J.P. Divided We Fall: Particulate Hexavalent Chromium Targets Securin Driving Premature Centriole Separation. Graduate Student Regional Research Conference, March 2021.

Toyoda, J.H., Martino, J., and Wise, Sr., J.P. When Your Chainsaw Loses Its Safety Lock: A Hypothesis for Metal-Induced Lung Cancer. Presented at the Annual Meeting of the Society of Toxicology (SOT), March 2021.

Wise, Jr., J.P. Cai, L., and Wise, Sr., J.P. Two Sides of Toxic Coin: Heavy Metals and Aging. Presented at the Annual Meeting of the Society of Toxicology (SOT), March 2021.

Lu, H., Wise, S.S., and Wise, Sr., J.P. Can Whales Resist Chromium-Induced Cancer? Presented at the Annual Meeting of the Society of Toxicology (SOT), March 2021.

Meaza, I., Wise, S.S., Perkins, C., and Wise, Sr., J.P. Save the Whales a Solution to a Climate in Crisis! Presented at the annual meeting of the Society of Toxicology (SOT), April 2021

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., and Wise, Sr., J.P. Lung Cancer Secret Revealed! RAD51D: Culprit Protein Found! Presented at the annual meeting of the Society of Toxicology (SOT), April 2021

Wise, Jr., J.P. Cai, L., and Wise, Sr., J.P. Evaluation of Cr(VI) Neurotoxicity and Its Potential as a Brain Gerontogen. Toxicological Sciences, 180: 2469, 2021.

Wise, S.S., and Wise, Sr., J.P. Cells Exposed Chronically to Hexavalent Chromium Escape Cell Death and Develop Permanent Chromosome Instability. Toxicological Sciences, 180:2012, 2021.

Lu, H., Wise, S.S., Toyoda, J.H., Speer, R.M., Bolt, A., and Wise, Sr., J.P. Whale Cells Resist Cr(VI)-Induced Loss of Homologous Recombination Repair. Toxicological Sciences, 180:2087, 2021.

Williams, A.R., Speer, R.M., Browning, C.L., Meaza, I., Toyoda, J., and Wise, Sr., J.P. Particulate Hexavalent Chromium Inhibits DNA Repair by Targeting RAD51 Paralogs. Toxicological Sciences, 180:2081, 2021.

Toyoda, J.H., Martino, J., Speer, R.M., Wise, S.S., and Wise, Sr., J.P. Divided We Fall: Particulate Hexavalent Chromium Targets Securin Driving Premature Centriole Separation. Toxicological Sciences, 180:2078, 2021.

Meaza, I., Speer, R.M., Toyoda, J.H., Lu, Y., Xu, Q., Walter, R., Kong, M. and Wise, Sr., J.P. Particulate Hexavalent Chromium Altered the Expression of miRNAs Involved in Carcinogenesis Pathways. Toxicological Sciences, 180:2073, 2021.

Toyoda, J.H., Martino, J., Speer, R.M., and Wise, Sr., J.P. Hexavalent Chromium Decreases Securin Expression, and Increases Separase Substrate Cleavage in Human Lung Cells. Presented at the NIH/NIEHS Superfund Research Program Annual Meeting, December 2020.

Williams, A.R., Browning, C.L. Meaza, I., Toyoda, J., and Wise, Sr., J.P. Rad51 Paralogs Are Key Targets for Loss of Homologous Recombination Repair in Metal Carcinogenesis. Presented at the annual meeting of the Ohio Valley Society of Toxicology (OVSOT), November 2020.

Meaza, I., Speer, R.M., Toyoda, J.H., Lu, Y., Xu, Q., Walter, R., Kong, M. and Wis​e, Sr., J.P. Particulate Hexavalent Chromium Altered the Expression of miRNAs Involved in Carcinogenesis Pathways. Presented at the annual meeting of the Ohio Valley Society of Toxicology (OVSOT), November 2020.

Lu, H., Wise, S.S., Toyoda, J.H., Speer, R.M., Bolt, A. and Wise, Sr., J.P. Whale Cells Are Resistant to Cr(VI)-Induced Loss of Homologous Recombination Repair. Presented at the annual meeting of the Ohio Valley Society of Toxicology (OVSOT), November 2020.

Toyoda, J.H., Martino, J., Kondo, K., and Wise, Sr., J.P. Prolonged Particulate Hexavalent Chromium Exposure Disrupts Centrosome Regulation Proteins and Causes Centrosome Amplification. Presented at the summer meeting of the Ohio Valley Society of Toxicology (OVSOT), July 2020.

Williams, A.R., Speer, R.M., Browning, C. Meaza, I., Toyoda J., and Wise, Sr., J. P. Particulate Hexavalent Chromium Inhibits DNA Repair by Targeting RAD51 Paralogs. Presented at the summer meeting of the Ohio Valley Society of Toxicology (OVSOT), July 2020.

Meaza I., Speer M.R., Toyoda, J.H., Lu H., Wise S.S. Croom-Perez J.T., El-Makarim, A. and Wise, Sr., J. P. Prolonged exposure to particulate Cr(VI) is cytotoxic and genotoxic to fin whale cells. Presented at the summer meeting of the Ohio Valley Society of Toxicology (OVSOT), July 2020.

Wise, S.S., and Wise, Sr., J.P. The Fate of Cells that Escape Cr(VI)-induced Cell Death. Toxicological Sciences, 174(1): 2603, 2020.

Meaza, I., Speer, R.M, Toyoda, J.H. and Wise, Sr., J.P. Particulate Hexavalent Chromium Induces Cytotoxicity and Genotoxicity in Female and Male Fin Whale Cells. Toxicological Sciences, 174(1): 2565, 2020.

Lu H., Browning C.L. and Wise, Sr., J.P. Why Do Whales Have Lower Cancer Rates: Whale Cells Avoid Particulate Chromate Induced Homologous Recombination Repair Inhibition. Toxicological Sciences, 174(1): 1339, 2020.

Wise, Jr., J.P., Lu, H., Toyoda, J.H., Speer, R.M., Croom-Perez, T., Meaza Isusi, I., Wise, S.S., Young, J.L. Tan, Y., Hoyle, G., Isakov, R., Jaggers, H., Wise, Sr., J.P., and Cai, L. Genotoxicity in the Heart-Brain Axis Following Inhalation of Hexavalent Chromium [Cr(VI)] in a Rat Model. Toxicological Sciences, 174(1): 3130, 2020.

Toyoda, J.H., Martino, J., Kondo, K., and Wise, Sr., J.P. Prolonged Particulate Hexavalent Chromium Exposure Disrupts Centrosome Regulation Proteins and Causes Centrosome Amplification. Toxicological Sciences, 174(1): 2607, 2020.

Speer, R.M., Zhou, X., Liu, K.J., Browning, C.L., Kondo, K. and Wise, Sr., J.P. Chromate-Induced Loss of E2F1 Inhibits RAD51 Response in Homologous Recombination Repair. Toxicological Sciences, 174(1): 2600, 2020.

Toyoda, J.H., Martino, J., Kondo, K., and Wise, Sr., J.P. Prolonged Particulate Hexavalent Chromium Exposure Disrupts Centrosome Regulation Proteins and Causes Centrosome Amplification. Graduate Student Council Regional Research Conference, February 2020.

2010-2019

Poirier, Lair, Michaud, Hernandez-Ramon, Divi, Dwyer, Loseto, Raverty, St. Leger, Van Bonn, Colegrove, Burek-Huntington, Suydam, Stimmelmayr, Wise, Sr., J.P., Wise, S., Beauchamp and Martineau, D. Evidence of DNA Damage links exposure to gastrointestinal cancers in St. Lawrence Estuary Beluga. Presented at the World Marine Mammal Science Conference, Barcelona, Spain, December 2019.

Meaza, I., Speer, R.M., Toyoda, J.H., and Wise, Sr., J.P. The Characterization of the Toxicologic Effects of Particulate Hexavalent Chromium in Female and Male Fin Whale Cells. Presented at the World Marine Mammal Science Conference, Barcelona, Spain, December 2019

Young, J.L., Wise, Jr., J.P., Wise, J.T.F., Wise, C.F., Wise, S.S., Zhu, C., Browning, C., Zheng T, Perkins C, Gianios, Jr, C., Xie H, Lu, C., and Wise, Sr., J.P. A Whale of a Tale:  A 3-Year Study of Metals in Gulf of Maine Whales. Presented at the World Marine Mammal Science Conference, Barcelona, Spain, December 2019.

Wise, Sr., J.P., Wise, Jr., J.P., Toyoda, J.H., Croom-Perez, T.J., Aboueissa, A., , Montalvo, C.L., Isusi, I.M., Wise, S.S., Wise, C.F., Wise, J.T.F., Li Chen, T., Perkins, C.R., Bras, M.M., Speer, R.M., and Urbán, J. Of Whales and Men: Understanding Metal Pollution in the Sea of Cortez through a One Environmental Health Approach. Presented at the World Marine Mammal Science Conference, Barcelona, Spain, December 2019.

Wise, Jr., J.P., Lu, H., Meaza, I., Wise, S.S., Croom-Perez, T., Speer, R., Toyoda, J., Ali, A., Cai, L., Liu, K.J., Wise, J.T.F., Young, J.L., and Wise, Sr., J.P. An Environmental Toxicology Assessment of Heavy Metal Accumulation in American Alligators in Florida. Presented at the annual meeting of the Ohio Valley Chapter of the Society of Toxicology (OVSOT), October 2019.

Lu, H., Browning, C.L, and Wise, Sr., J.P. Why Do Whales Have Lower Cancer Rates: Whale Cells Avoid Particulate Chromate Induced Homologous Recombination Repair Inhibition. Presented at the annual meeting of the Ohio Valley Regional Chapter of the Society of Toxicology (OVSOT), Cincinnati. Ohio, October 2019.

Meaza I., Speer, M.R., Toyoda, J.H. and Wise, Sr., J.P.  Particulate Hexavalent Chromium Induces Cytotoxicity and Genotoxicity in Female and Male Fin Whale Primary Cells. Presented at the annual meeting of the Ohio Valley Regional Chapter of the Society of Toxicology (OVSOT), Cincinnati. Ohio, October 2019.

Speer, R.M., Zhou, X., Liu, K.J., Browning, C.L., Kondo, K., and Wise, Sr., J.P. Chromate-Induced Loss of E2F1 Inhibits RAD51 Response in Homologous Recombination Repair. Presented at the annual meeting of the Ohio Valley Regional Chapter of the Society of Toxicology (OVSOT), Cincinnati. Ohio, October 2019.

Toyoda, J., Martino, J., Kondo, K., and Wise, Sr., J.P. Prolonged Particulate Hexavalent Chromium Exposure Disrupts Centrosome Regulation Proteins and Causes Centrosome Amplification. Presented at Ohio Valley Society of Toxicology (OVSOT) Annual Meeting, October 2019.

Croom-Perez, T.J., Meaza, I., and Wise, Sr., J.P. Chromate-Induced Changes in the Fibroblast Secretome and its Effects on Epithelial Cells. Presented at the annual meeting of the Ohio Valley Regional Chapter of the Society of Toxicology (OVSOT), Cincinnati. Ohio, October 2019.

Wise, Sr., J.P. and G, Jia. Metal Carcinogenesis:  Insights from Hexavalent Chromium and Arsenic. Presented at the 13th Conference of the International Society for Trace Element Research in Humans (ISTERH), Bali, Indonesia, September, 2019.

Wise, S.S., and Wise, Sr., J.P. Mechanism of Cr(VI)-induced Chromosome Instability. Presented at the 13th Conference of the International Society for Trace Element Research in Humans (ISTERH), Bali, Indonesia, September, 2019.

Lu, H., Browning, C.L, Wise, S.S., Toyoda, J.H., Speer, R.M., and Wise, Sr., J.P. Bowhead Whale Lung Cells Maintain Homologous Recombination Repair and Resist Genomic Instability during Prolonged Particulate Chromate Exposure. Presented at the Annual Meeting of the Environmental Mutagenesis and Genomics Society (EMGS), Washington, D.C., September, 2019.

Wise, Sr., J.P. and Kondo, K. The Carcinogenicity of Hexavalent Chromium:  A Global Public and Environmental Health Concern Proceedings of the XV International Congress of Toxicology (ICTXV), Honolulu, Hawaii, July, 2019.

Wise, S.S., Browning, C. Wise, Sr., J.P. and Mechanisms of Hexavalent Chromium-Induced Genomic Instability:  How a Lung Carcinogen Breaks DNA and Inhibits Repair. Proceedings of the XVI International Congress of Toxicology (ICTXV), Honolulu, Hawaii, July, 2019.

Croom-Perez, T.J., Meaza, I., and Wise, Sr., J.P. Chromate-Induced Changes in the Fibroblast Secretome and its Effects on Epithelial Cells. Presented at Research!Louisville, Louisville, Kentucky, 2019.

Isakov, R.V., Croom-Perez, T.J., Young, J.L., Jaggers, H.D., Cai, L., Hoyle, G.W., and Wise, Sr., J.P.  The Effects of Whole Life, Low Dose Cadmium Exposure on Mouse Lung Histology and DNA Damage. Presented at Research!Louisville, Louisville, Kentucky, 2019.

Jaggers, H.D., Croom-Perez, T.J., Young, J.L., Isakov, R.V., Cai, L., Hoyle, G.W., and Wise, Sr., J.P.  The Effects of Whole Life, Low Dose Cadmium Exposure on Mouse Lung Histology and DNA Damage Repair. Presented at Research!Louisville, Louisville, Kentucky, 2019.

Toyoda, J., Martino, J., Kondo, K., and Wise, Sr., J.P. Prolonged Particulate Hexavalent Chromium Exposure Disrupts Centrosome Regulation Proteins and Causes Centrosome Amplification. Presented at Research!Louisville, University of Louisville, Louisville, KY, September 2019.

Meaza I., Speer, M.R., Toyoda, J.H. and Wise, Sr., J.P.  Particulate Hexavalent Chromium Induces Cytotoxicity and Genotoxicity in Female and Male Fin Whale Primary Cells. Presented at Research! Louisville, Louisville, Kentucky 2019.

Wise, S.S., Miller, E., Daniel, S., Meaza, I., Toyoda, J.H., Lu, H., Speer, R. M., Young, J. L., Isakov, R., Jaggers, H., Wise, Jr., J. P., Croom-Perez, T. J., Cai, L., Hoyle, G., and Wise, Sr., J. P. Effects of Chronic Exposure to Particulate Chromate in Rat Lungs. Presented at Research!Louisville, Louisville, Kentucky, 2019.

Speer, R.M., Zhou, X., Liu, K.J., Browning, C.L., Kondo, K., and Wise, Sr., J.P. Chromate-Induced Loss of E2F1 Inhibits RAD51 Response in Homologous Recombination Repair. Presented at Research!Louisville!, 2019.

Lu, H., Browning, C.L, and Wise, Sr., J.P. Why Do Whales Have Lower Cancer Rates: Whale Cells Avoid Particulate Chromate Induced Homologous Recombination Repair Inhibition. Presented at Research!Louisville, Louisville, Kentucky, 2019.

Wise, Sr., J.P., Toyoda, J.H., Croom-Perez, T.J., Wise, S.S. Whale Cells Are Resistant to Metal-Induced Chromosome Instability and Centrosome Amplification. Presented at the triennial meeting of the EMBO workshop: Chromosome Segregation and Aneuploidy, Cascais, Portugal, May, 2019.

Wise, Jr., J.P., Croom-Perez, T.J., Meaza, I., Montalvo, C.L., Wise, C.F., Wise, S.S., Wise, J.T.F., Speer, R.M., Abouiessa, A., Bras, M.M., Savery, L.C., Urbán, J., Young, J.L., and Wise, Sr., J.P. A Whale of a Tale: A One Environmental Health Approach to Study Metal Pollution in the Sea of Cortez. Presented at the Annual Meeting of the Society of Toxicology (SOT), Baltimore, Maryland, March, 2019.

Wise, S.S. Daniel, S. and Wise, Sr., J.P. The fate of cells that escape Cr(VI)-induced cell death. Presented at the Annual Meeting of the Society of Toxicology (SOT), Baltimore, Maryland, March, 2019.

Lu, H., Browning, C.L, Wise, S.S., Toyoda, J.H., and Wise, Sr., J.P. Homologous Recombination Repair Protects Against Genomic Instability in Bowhead Whale Lung Cells After Prolonged Particulate Chromate Exposure. Presented at the Annual Meeting of the Society of Toxicology (SOT), Baltimore, Maryland, March, 2019.

Toyoda, J.H., Croom-Pérez, T. J., Wise, S.S., and Wise, Sr., J.P. Particulate Hexavalent Chromium Does Not Induce Centrosome Amplification in Sperm Whale and Bowhead Whale Cells. Presented at the Annual Meeting of the Society of Toxicology (SOT), Baltimore, Maryland, March, 2019.

Croom-Perez, T.J., Ziemba, C.R., Anglin, C.R., and Wise, Sr., J.P. The Cytotoxic and Genotoxic Effects of Prolonged Particulate Hexavalent Chromium Exposure on Human Lung Epithelial Cells. Presented at the Annual Meeting of the Society of Toxicology (SOT), Baltimore, Maryland, March, 2019.

Speer, R.M., Browning, C.L., and Wise, Sr., J.P. Suppression of E2F1 and RAD51 in Chromate-Induced Failure of Homologous Recombination. Presented at the annual meeting of the Society of Toxicology (SOT), Baltimore, Maryland, March, 2019.

Speer, R.M., Wise, C.F., Wise, S.S., Martin Bras, M., Barandiarin, M., Marquez, L., Bermudez, E., and Wise, Sr., J.P.  Environmental Impacts on Leatherback Sea Turtle Health: Using a One Health Approach to Study Metal Pollution in WIldlife. Presented at the International Sea Turtle Symposium, February, 2019.

Wise, S.S., Toyoda, J.H., and Wise, Sr., J.P. Chromosomal instability drives hexavalent chromium-induced carcinogenesis in human lung cells. Presented at the American Society for Cell Biology (ASCB)/EMBO Conference, San Diego, California, December, 2018.

Lu, H., Browning, C.L, Wise, S.S., Toyoda, J.H., and Wise, Sr., J.P. Prolonged Particulate Chromate Exposure Does Not Inhibit Homologous Recombination Repair in Bowhead Whale Lung Cells. Presented at the annual meeting of the Ohio Valley Regional Chapter of the Society of Toxicology (OVSOT), Louisville, Kentucky, November, 2018.

Toyoda, J.H., Croom-Pérez, T. J., Wise, S.S., and Wise, Sr., J.P. Particulate Hexavalent Chromium Does Not Induce Centrosome Amplification in Sperm Whale and Bowhead Whale Cells. Presented at the annual meeting of the Ohio Valley Regional Chapter of the Society of Toxicology (OVSOT), Louisville, Kentucky, November, 2018.

Croom-Perez, T.J., Ziemba, C.R., Anglin, C.R., Furtado, W.R., and Wise, Sr., J.P. Establishing a Model Human Lung Fibroblast-Epithelial Co-Culture System to Study Chromate-Induced Effects on Cell-Cell Interactions. Presented at the annual meeting of the Ohio Valley Regional Chapter of the Society of Toxicology (OVSOT), Louisville, Kentucky, November, 2018.

Speer, R.M., Browning, C.L., and Wise, Sr., J.P. Suppression of E2F1 and RAD51 in Chromate-Induced Failure of Homologous Recombination. Presented at the annual meeting of the Ohio Valley Regional Chapter of the Society of Toxicology (OVSOT), Louisville, Kentucky, November, 2018.

Wise, Sr., J.P., Toyoda, J.H., Wise, S.S., Croom-Pérez, T., Martino, J., Holmes, A., and Xie, H. Chromosme Instability in Metal Carcinogenesis: Mechanisms of Particulate Cr(VI) Induced Centrosome Amplification from a One Environmnetal Health Perspective. Presented at the 10th Conference on Metal Toxicity & Carcinogenesis, Albuquerque, New Mexico, October 2018.

Wise, Sr., J.P., Wise, S.S., Speer, R.M., Toyoda, J.H. and Meaza, I. Caracterización de los Efectos Toxicológicos del Cromo Particulado Hexavalente en Cultivos Celulares Primarios de Rorcual Común y Yubarta (Characterization of the Toxicological Effects of Particulate Hexavalent Chromium in Fin Whale and Humpback Whale Primary Cell Cultures). Congreso de la Sociedad Española de Cetaceos (Spanish Society of Cetaceans Congress), Bilbao, Spain, October 2018.

Wise, Sr., J.P., Wise, Jr., J.P., Wise, J.T.F., Wise, C.F., Wise, S.S., Browning, C.L. Martino, J., and Li Chen, T. A Whale of a Tale: Metals and Genotoxicity in Great Whales Considered from a One Health Perspective. Environmental and Molecular Mutagenesis 59(S1): S30 p 42, 2018.

Lu, H., Browning, C.L. and Wise, Sr., J.P. Autophagy Does Not Play A Main Role in Rad51 Dysfunction after Prolonged Cr(VI) Exposure in Human Lung Cells. Presented at the Graduate Student Regional Research Conference, University of Louisville, 2018.

Speer, R.M., Young, J.L., Wise, S.S., Raph, S.M., Martin Bras, M., Barandiarin, M., Marquez-D’Acunti, L., and Wise, Sr., J.P. Using Leatherback Sea Turtles (Dermochelys coriacea) as a Model Species for Metal Toxicology Research and Public Education in Vieques, Puerto Rico. Presented at the Graduate Student Regional Research Conference, University of Louisville, 2018.

Toyoda, J.H., Martino, J. and Wise, Sr., J.P. Mechanisms of Hexavalent Chromium-Induced Centriole Disengagement and Centrosome Amplification. Presented at the Graduate Student Regional Research Conference, University of Louisville, 2018.

Raph, S.M., Wise, S.S., and Wise, Sr., J.P. One Environmental Health Cytotoxicity and Genotoxicity of Hexavalent Chromium in American Alligator (Alligator mississippiensis). Presented at the Graduate Student Regional Research Conference, University of Louisville, 2018.

Toyoda, J.H., Croom-Perez, T.J., Wise, S.S., and Wise, Sr., J.P. Particulate Hexavalent Chromium Does Not Induce Centrosome Amplification in Sperm Whale and Bowhead Whale Cells. Presented at Research!Louisville, Louisville, Kentucky, October 2018.

Anglin, C.T., Croom-Perez, T.J., and Wise, Sr., J.P. The Cytotoxic and Genotoxic Effects of Prolonged Particulate Hexavalent Chromium Exposure on Human Epithelial Cells. Presented at Research!Louisville, Louisville, Kentucky, 2018.

Ziemba, C.R., Anglin, C.R., Croom-Perez, T.J., Wise, S.S., and Wise, Sr., J.P. Effects of Prolonged Hexavalent Chromium Exposure on Homologous DNA Recombination in Human Epithelial Cells Grown in Minimal Serum Media. Presented at Research!Louisville, Louisville, Kentucky, 2018.

Croom-Perez, T.J., Ziemba, C.R., Anglin, C.R., Furtado, W.R., and Wise, Sr., J.P. Establishing a Model Human Lung Fibroblast-Epithelial Co-Culture System to Study Chromate-Induced Effects on Cell-Cell Interactions. Presented at Research!Louisville, Louisville, Kentucky, 2018.

Geisen, M.E., Toyoda, J.H., Croom-Perez, T.J., and Wise, Sr., J.P. Comparative Effects of Particulate Hexavalent Chromium on Mitotic Stages in Human and Whale Lung Fibroblasts. Presented at Research!Louisville, Louisville, Kentucky, 2018.

Daniel, S., Wise, S.S., and Wise, Sr., J.P. The Impact of Prolonged Particulate Hexavalent Chromium Exposure on Human Lung Fibroblasts. Presented at Research!Louisville, Louisville, Kentucky, 2018.

Raph, S.M., Wise, S.S., and Wise, Sr., J.P. One Environmental Health: A Study of the Genotoxic Effects of Hexavalent Chromium in American alligator (Alligator mississippiensis) Lung Fibroblasts. Presented at Research!Louisville, Louisville, Kentucky, 2018.

Speer, R.M., Browning, C.L, and Wise, Sr., J.P. Suppression of E2F1 and RAD51 in Chromate-Induced Failure of Homologous Recombination. Presented at Research!Louisville, Louisville, Kentucky, 2018.

Lu, H., and Wise, Sr., J.P. Homologous Recombination Repair Protects against Genomic Instability in Bowhead Whale Lung Cells after Prolonged Particulate Chromate Exposure. Presented at Research!Louisville, Louisville, Kentucky, 2018.

Wise, Sr., J.P. and Martineau, D. Environmental Exposure, Genotoxicity and Cancer Risk in Whales. Presented at the annual meeting of the Environmental Mutagenesis and Genomics Society, San Antonio, Texas, September, 2018.

Wise, Sr., J.P., Wise, S.S., Browning, C.L., Toyoda, J.H., Martino, J., and Xie, H. Chromosomal Instability Is a Key Step in the Carcinogenic Mechanism of Hexavalent Chromium. P88, page 154. Presented at the EMBO Conference: DNA replication, chromosome segregation and fate decisions, Kyllini, Greece, September, 2018.

Speer, R.M., Browning, C.L., and Wise, Sr. J.P. Mechanisms of E2F1 Suppression of RAD51 in Chromate-Induced Failure of Homologous Recombination. Presented at the 20th Annual Midwest DNA Repair Symposium, Columbus, Ohio, May, 2018.

Wise, Jr., J.P. Montalvo, C.L., Wise, C.F., Wise, S.S., Wise, J.T.F., Speer, R.M., Li Chen, T., Abouiessa, A., Perkins, C., Bras, M.M., Savery, L.C., Urbán, J. and Wise, Sr., J.P. Of Whales and Men: A One Health Approach to Study Metal Pollution in the Sea of Cortez. Presented at the annual meeting of the International Association for Aquatic Animal Medicine (IAAAM), Long Beach, California, May, 2018.

Poirier, M.C., Lair, S., Hernandez-Ramon, E.E., Divi, K.V., Raverty, S., St. Leger, J.A., Burek-Huntington, K.A., Wise, S.S., Wise, Sr., J.P., Beauchamp, G., and Martineau, D. Intestinal Polycyclic Aromatic Hydrocarbon (PAH)-DNA Adducts in Beluga Whales with PAH-Exposures and High Rates of Gastrointestinal Cancers. Toxicological Sciences, 150(1): 242, 2018.

Croom-Pérez, T.J., Toyoda, J.H., Wise, S.S. and Wise, Sr., J.P. Chronic Exposure to Particulate Hexavalent Chromium Induces Centrosome Abnormalities and Disrupts Mitosis in both Sea Turtle and Alligator Primary Lung Cells. Toxicological Sciences, 150(1): 480, 2018.

Wise, S.S. and Wise, Sr., J.P. Cells that escape Cr(VI)-induced cell death exhibit chromosome instability. Toxicological Sciences, 150(1): 252, 2018.

Speer, R.M., Browning, C.L. and Wise, Sr., J.P. Chromate-Induced Suppression of E2F1 and RAD51 in the Homologous Recombination Response. Toxicological Sciences, 150(1): 480, 2018.

Wise, Jr., J.P. Montalvo, C.L., Wise, C.F., Wise, S.S., Wise, J.T.F., Speer, R.M., Li Chen, T., Abouiessa, A., Perkins, C., Bras, M.M., Savery, L.C., Urbán, J. and Wise, Sr., J.P. A Whale of a Tale: Using a One Health Approach to Study Metal Pollution in the Sea of Cortez. Presented at the annual meeting of the Southern California Marine Mammal Workshop (SCMMW), Newport Beach, California, January, 2018.

Raph, S., Wise, S.S. and Wise, Sr., J.P. One Environmental Health: Cytotoxicity and Genotoxicity of Hexavalent Chromium in American Alligator (Alligator mississippiensis). Presented at the Ohio Valley Chapter of the Society of Toxicology (OVSOT) annual meeting, December, 2017.

Croom-Pérez, T.J., Toyoda, J.H., Wise, S.S. and Wise, Sr., J.P. Chronic Exposure to Particulate Hexavalent Chromium Induces Centrosome Abnormalities and Disrupts Mitosis in both Sea Turtle and Alligator Primary Lung Cells. Presented at the Ohio Valley Chapter of the Society of Toxicology (OVSOT) annual meeting, December, 2017.

Speer, R.M., Browning, C.L. and Wise, Sr., J.P. Chromate-Induced Suppression of E2F1 and RAD51 in the Homologous Recombination Response. Presented at the Ohio Valley Chapter of the Society of Toxicology (OVSOT) annual meeting, December, 2017.

Wise, Sr., J.P., Wise, Jr., J.P., Wise, J.T.F., Wise, C.F., Wise, S.S., Browning, C.L., Martino, J., and Li Chen, T. Of Whales and Men: Using a One Health Perspective to Understanding Chromium Pollution in Great Whales. Presented at the annual meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Minneapolis, Minnesota, November, 2017.

Wise, Sr., J.P., Wise, S.S., Martino, J., and Xie, H. Centrosomes in Chemical Carcinogenesis: Chromosomal Instability, Centrosome Amplification, and Premature Centriole Disengagement Are Key Steps in the Carcinogenic Mechanism of Hexavalent Chromium. Presented at the EMBO conference: Centrosomes and Spindle Pole Bodies, p.221, Heidelberg, Germany, September, 2017.

Wise, S.S., and Wise, Sr., J.P. Chronic exposure to particulate chromate induces altered growth parameters and chromosome instability in human lung cells. Presented at the annual meeting of the Environmental Mutagenesis and Genomics Society, Raleigh, North Carolina, September, 2017, Environmental and Molecular Mutagenesis, 58 (S1): S48, 2017.

Wise, Sr., J.P., Wise, Jr., J.P., Wise, J.T.F., Wise, C.F., Wise, S.S., Browning, C.L., Martino, J., and Li Chen, T. A Whale of a Tale: Lessons from Moby Dick’s Descendants about Global Chromium Pollution. Presented at the 14th International Symposium on Recent Advances in Environmental Health Research, Jackson, Mississippi, September, 2017.

Speer, R.M., Browning, C.L. and Wise, Sr., J.P. Chromate-Induced Suppression of E2F1 and RAD51 in the Homologous Recombination Response. Presented at Research!Louisville, University of Louisville, September 2017.

Raph, S., Wise, S.S. and Wise, Sr., J.P. One Environmental Health: Cytotoxicity and Genotoxicity of Hexavalent Chromium in American Alligator (Alligator mississippiensis). Presented at Research!Louisville, University of Louisville, 2017.

Lu, H., Browning, C.L. and Wise, Sr., J.P. Autophagy Does Not Play A Main Role in Rad51 Dysfunction after Prolonged Cr(VI) Exposure in Human Lung Cells. Presented at Research!Louisville, University of Louisville, 2017.

Wise, S.S. and Wise, Sr., J.P. Cells that escape Cr(VI)-induced cell death exhibit chromosome instability. Presented at Research!Louisville, University of Louisville, 2017.

McBride, D.E., Perez, A.A., Raph S.M., Speer R.M., Croom-Perez T.J., Wise S.S. and Wise, Sr., J.P. A One Health Case Study: Comparison of DNA Damage Response to Hexavalent Chromium in Alligator and Human Lung Fibroblasts. Presented at Research!Louisville, University of Louisville, 2017.

Toyoda, J.H., Martino, J., Speer, R.M. and Wise, Sr., J.P. Mechanisms of Hexavalent Chromium-Induced Centriole Disengagement and Centrosome Amplification. Presented at Research!Louisville, University of Louisville, 2017.

Pérez, A. A., Wise, S.S. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Particulate Hexavalent Chromium in the Normal Human Lung Fibroblasts (NHLF) Primary Cell Line. Presented at Research!Louisville, University of Louisville, 2017.

Croom-Pérez, T.J., Martino, J., Wise, S.S. and Wise, Sr., J.P. Chronic Exposure to Particulate Hexavalent Chromium Induces Centrosome Abnormalities in Primary Human Lung Cells. Presented at Research!Louisville, University of Louisville, 2017.

Hernandez-Ramon, E.E., Wise, Sr., J.P., Si, N., Wise, S.S., Wise, Jr., J.P. and Poirier, M.C. Detection of polycyclic aromatic hydrocarbon-DNA adducts in epidermis from whales. First International Symposium of Environmental and Regulatory Toxicology and Fourth International Meeting of Pharmaceutical and Food Sciences (ECFA), Havana, Cuba, July, 2017.

Wise, Sr., J.P., Wise, C.F., Wise, Jr., J.P., Browning, C.L., Martino, J., Li Chen, T., Wise, S.S., and Wise, J.T.F. Insights into the Threat of Chromium on Whale Health: As a One Environmental Health Approach. Presented at the 56th Annual Meeting of the International Association of Aquatic Animal Medicine (IAAAM). Cancun, Mexico, May, 2017.

Wise, Sr., J.P., Browning, C.L., Wise, S.S., Speer, R., and Lu, H. Homologous Recombination Repair in Chemical Carcinogenesis: Hexavalent Chromium Induces DNA Strand Breaks while Targeting Rad51 to Inhibit Their Repair. Presented at the 19th Annual Midwest DNA Repair Symposium, p. 16, Dayton, Ohio, May, 2017.

Zhou, X., Liu, K.J., and Wise, Sr, J.P. Cr(III) Intreacts with Acetylated Histones. Toxicological Sciences, 156(1): 263, 2017.

Wise, S.S., and Wise, Sr., J.P. Chronic Exposure to Particulate Chromate Induces Altered Growth Parameters and Chromosome Instability in Human Lung Cells. Toxicological Sciences, 156(1): 3455LB, 2017.

Speer, R.M., Young, J.L., Wise, S.S., Raph, S.M., Martin Bras, M., Barandiarin, M., Marquez-D’Acunti, L., and Wise, Sr., J.P. Using Leatherback Sea Turtles (Dermochelys coriacea) as a Model Species for Metal Toxicology Research and Public Education in Vieques, Puerto Rico. Toxicological Sciences, 156(1): 263, 2017.

Wise, Sr., J.P. One Health: Integrated Metal Toxicity from Ecology, Environment and Animal to Human Health. 156(1): 1005, 2017.

Browning, C.L. and Wise Sr., J.P. Differences in Genotoxicity and DNA Double Strand Break Repair in Whale Cells and Human Cells after Particulate Hexavalent Chromium Exposure. Toxicological Sciences, 150(1): 452, 2016.

Young, J.L., Wise, S.S., Wise, C.F., Fukuda, T., and Wise, Sr., J.P. Insights into Chromate Genotoxicity from a One Environmental Health Perspective: Alligators, Turtles, and Whales Oh My! Toxicological Sciences, 150(1): 126, 2016.

Wise, Sr., J.P. Mechanisms for Cr(VI) Induced Carcinogenicity: Perspectives from Past and Current Research. Toxicological Sciences, 150(1): 9, 2016.

Speer, R.M., The, T., and Wise Sr., J.P. Comparison of the Cytotoxicity and Genotoxicity of Particulate and Soluble Hexavalent Chromium in Human and Leatherback Sea Turtle (Dermochelys coriacea) Skin Cells Toxicological Sciences, 150(1): 154 LB, 2016.

Savery, L.C., Li Chen, T., Wise, J.T.F., Wise, S.S., Gianios, Jr. C., Buonagurio, J., Perkins, C., Zheng, T., Zhu, C., and Wise, Sr., J.P. Global Assessment of Cadmium Concentrations in the Skin of Free-Ranging Sperm Whales (Physeter macrocephalus). Toxicological Sciences, 150(1): 152LB, 2016.

Wise, S.S., Savery, L.C., Wise, J.T.F., Gianios, Jr. C., Buonagurio, J., Perkins, C., Zheng, T., Zhu, C., and Wise, Sr., J.P. Global Assessment of Manganese Concentrations in the Skin of Free‐Ranging Sperm Whales (Physeter macrocephalus). Toxicological Sciences, 150(1): 155LB, 2016.

Young, J.L., Wise, S.S., Xie,H., Wise, C.F., Fukuda, T., and Wise, Sr., J.P. A One Environmental Health Perspective: Insight into the Cytotoxic and Genotoxic Effects of Hexavalent Chromium in Human, Aquatic Reptile and Aquatic Mammal Skin Cells. Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 2016.

Speer, R.M., Young, J.L., Martin Bras, M., Barandiarin, M., Marquez, L., and Wise, Sr., J.P. A Comparison of the Cytotoxicity and Genotoxicity of Particulate and Soluble Hexavalent Chromium in Human and Leatherback Sea Turtle (Dermochelys coriacea) Skin Cells. Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 2016.

Wise, Sr., J.P., Wise, S.S., Martino, J., Holmes, A.L., and Xie, H. Chromosome Instability in Chemical Carcinogenesis: The Carcinogenic Mechanisms of Particulate Cr(VI) Involves Chromosomal Instability. Centrosome Amplification, and Premature Centriole Disengagement. Proceedings of the EMBO workshop: Chromosome segregation and aneuploidy. June 2016.

Martino, J., Holmes, A.L., Wise, S.S., Xie, H., and Wise, Sr., J.P., The Role of Centrosomes in Chemical Carcinogenesis: Hexavalent Chromium Induces Aberrant Centriole and Centrosome Separation and Centrosome Amplification. Proceedings of the XIV International Congress of Toxicology, S81.1, 2016.

Wise, Sr., J.P., and Browning, C.L. DNA Repair in Lung Carcinogenesis: Hexavalent Chromium Inhibits Homologous Recombination Repair. Proceedings of the Kentucky Lung Cancer Symposium, 18, 2016.

Wise, Sr., J.P., Browning, C.L., and Wise, S.S. The Impact of Prolonged Particulate Hexavalent Chromium Exposure on DNA Double Strand Break Repair. Proceedings of the 9th Conference on Metal Toxicity and Carcinogenesis, 70, 2016.

Zhou, X., Liu, K.J., and Wise, Sr., J.P. Cr(III) Interacts with Acetylated Histone. Proceedings of the 9th Conference on Metal Toxicity and Carcinogenesis, 16, 2016.

Speer, R.M., Young, J.L., Martin Bras, M., Barandiaran, M.. Marquez-D’Acunti, L., and Wise, Sr., J.P. A Comparison of the Cytotoxicity and Genotoxicity of Particulate and Soluble Hexavalent Chromium in Human and Leatherback sea Turtle (Dermochelys coriacea) Lung Cells. Proceedings of the 9th Conference on Metal Toxicity and Carcinogenesis, 4, 2016.

Young, J.L., Wise, S.S., Wise, C.F., Speer, R.M., Raph, S.M. Lowers, R., Hall, C., Phillipps, L., Guillette, Jr., L.J., and Wise, Sr., J.P. Using the American alligator (Alligator mississippiensis) as a Representative Species to Study Environmental Toxicology using a One Environmental Health Approach at Kennedy Space Center. Proceedings of the 3^rd Biennial Symposium on the Biology and Ecotoxicology of the American Alligator, 2016.

Speer, R.M., Young, J.L., Martin Bras, M., Barandiaran, M.. Marquez-D’Acunti, L. and Wise, Sr., J.P. A Comparison of the Cytotoxicity and Genotoxicity of Particulate and Soluble Hexavalent Chromium Leatherback Sea Turtle (Dermochelys coriacea) Lung Cells. Research!Louisville, 2016.

Rossman, J., Speer, R.M., Sandra S. Wise and Wise Sr., J.P. Cytotoxic Effects of Chromate Exposure on Alligotr Skin and Bronchial Cells. Presented at Research!Louisville, University of Louisville, 2016.

Browning, C.L. and Wise Sr., J.P. Inhibition of a High Fidelity DNA Repair Pathway by the Environmental Pollutant, Hexavalent Chromium. Presented at the Annual Meeting of the Graduate School of Biomedical Science and Engineering, University of Maine, September 2016.

Wise, Sr., J.P. “Double Trouble in Chemical Carcinogenesis: How Hexavalent Chromium Inhibits DNA Repair after Causing DNA Damage” Presented at the University of California, Riverside, Riverside, California, 2015.

Wise, Sr., J.P. “One Environmental Health: Insights into the Potential Long-Term Health Impacts of the Gulf of Mexico Oil Crisis Learned from Whale Cells and Tissues.”, Presented at the annual meeting of the Environmental Mutagenesis and Genomics Society, New Orleans, Lousiana, 2015.

Browning, C.L., Xie, H., Kelly, D.F. and Wise Sr., J. P. The Role of RAD51 in Chemical Carcinogenesis: Prolonged Exposure to Particulate Chromate Inhibits Filament Formation and Induces Cytoplasmic Accumulation. Proceedings of the Keystone Symposia on DNA Repair, 115, 2015.

Martino, J., Holmes, A.L., Xie, H., Thompson, W.D. and Wise, Sr., J.P. Centriole Defects in Chemical Carcinogenesis: Particulate Cr(VI) Causes Premature Centriole Disengagement through Plk1 and Separase Activation. Toxicological Sciences, 144: 69, 2015.

Browning, C.L., Xie, H., Kelly, D.F. and Wise, Sr., J.P. The Inhibition of DNA Repair Protein, RAD51, by Prolonged Exposure to Particulate Chromate. Toxicological Sciences, 144: 68, 2015.

Falank, C. and Wise, Sr., J.P. Chronic exposure to particulate hexavalent chromium disrupts sister chromatid cohesion in human lung cells. Toxicological Sciences, 144: 68, 2015.

Thompsom, K.N., Qin, Q., Xie, H., and Wise, Sr., J.P., Investigating the Effect of Hexavalent Chromium on an Error-Prone Repair Pathway, Non-Homologous End Joining. Toxicological Sciences, 144: 116, 2015.

Wise, S.S., Xie, H., Fukuda, T., Thompson, W.D., Guillette, Jr., L.J. and Wise, Sr., J.P. Assessing the Effects of Hexavalent Chromium in Two Reptilian Species: Implications for Metal Impacts of Global Warming. Toxicological Sciences, 144: 68, 2015.

Speer, R.M., The, T., and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Particulate and Soluble Cobalt in Human Urothelial Cells. Toxicological Sciences, 144: 75, 2015.

Xie, H., Wise, Sr., J.P., Stewart, J., Yang, L., and Nutter, N. Mechanism of Arsenic Synergistic Effect on Hexavalent Chromium-induced Metaphase Damage in Human Lung Cells. Toxicological Sciences, 144: 424, 2015.

Savery, L.C., Wise, J.T.F., Wise, S.S., Falank, C., Gianios, Jr., C., Thompson, W.D., Perkins, C., Zheng, T., Zhu, C., and Wise, Sr., J.P. Global Assessment of Copper and Zinc Concentrations in Free-Ranging Sperm Whales (Physeter macrocephalus) As an Indicator Species. Toxicological Sciences, 144: 72, 2015.

Wise, Sr., J.P., Browning, C.L., Wise, S.S., Qin, Q., Kelly, D.F., Jasin, M., Prakash, R., and Xie, H. How a Carcinogen Evades Repair: The Mechanisms of Chromate Inhibition of DNA Double Strand Break Repair. Proceedings of the 5th Georgian Bay International Conference on Bioinorganic Chemistry, 44, 2015.

Young, J.L., Wise, S.S., Xie, H., Wise, C.F., Fukuda, T., Guillette, Jr., L., and Wise, Sr., J.P. A Comparison of the Cytotoxic and Genotoxic Effects of Hexavalent Chromium in Human, Sea Turtle, and Alligator Skin Cells. Proceedings of the 5th Georgian Bay International Conference on Bioinorganic Chemistry, 64, 2015.

Wise, S.S., Martino, J., and Wise, Sr., J.P. Hexavalent Chromium Induces Permanent and Heritable Chromosome Instability in Human Lung Cells. Proceedings of the 5th Georgian Bay International Conference on Bioinorganic Chemistry, 65, 2015.

Wise, Jr., J.P., Wise, J.T.F., Wise, C.F., Wise, S.S., Gianios, Jr., C., Xie, H., Thompson, W.D., Perkins, C. and Wise, Sr., J.P. One Environmental Health: Insights into the Potential Long-Term Health Impacts of the Gulf of Mexico Oil Crisis Learned From Whale Cells and Tissues. Environmental and Molecular Mutagenesis, 56(S1): S24, 2015.

Young, J.L., Wise, S.S., Xie, H., Wise, C.F., Fukuda, T. Lou Guillette, Jr. and Wise, Sr., J.P. A Comparison of the Cytotoxic and Genotoxic Effects of Hexavalent Chromium in Human, Aquatic Reptile and Aquatic Mammal Skin Cells. Environmental and Molecular Mutagenesis, 56(S1): P71, 2015.

Wise, Jr., J.P., Wise, J.T.F., Wise, C.F., Wise, S.S., Gianios, Jr., C., Xie, H., Thompson, W.D., Perkins, C. and Wise, Sr., J.P. The Impact of the Deepwater Horizon on Whales: A 3-Year Study of Metal Levels in Gulf Sperm Whales in Aftermath of the Spill. Proceedings of the 21st Biennial Conference on the Biology of Marine Mammals, 2015.

Wise, S.S., Wise, J.T., Wise, C.F., and Wise, Sr., J.P. Chemical Dispersants, Oil and Chemically Dispersed Oil Are Toxic to Sperm Whale Skin Cells. Proceedings of the 21st Biennial Conference on the Biology of Marine Mammals, 2015.

Browning, C.L., Wise Jr, J.P., Wise, J.T.F., Wise, C.F., Perkins, C.R., Thompson, W.D. and Wise Sr., J.P. Metal and Essential Element Levels in Three Baleen Whale Species in the Gulf of Maine (2010-2012). Proceedings of the 21st Biennial Conference on the Biology of Marine Mammals, 2015.

Savery, L.C., Wise, J.T.F., Wise, S.S., Gianios, Jr., C., Perkins, C., Buonagurio, J., Zheng, T., Zhu, C. and Wise, Sr., J.P. Copper and Zinc Concentrations in the Skin of Free-Ranging Sperm Whales (Physeter macrocephalus) from Around the Globe. Proceedings of the 21st Biennial Conference on the Biology of Marine Mammals, 2015.

Young, J.L., Wise, S.S., Xie, H., Wise, C.F., and Wise, Sr., J.P. Whale Cells May Have More Efficient Cellular Mechanisms Against Chromium Induced Genotoxicity Than Both Human and Turtle Cells. Proceedings of the 21st Biennial Conference on the Biology of Marine Mammals, 2015.

Browning, C.L., Xie, H., Kelly, D.F. and Wise Sr., J. P. The Role of RAD51 in Chemical Carcinogenesis: Prolonged Exposure to Particulate Chromate Inhibits Filament Formation and Induces Cytoplasmic Accumulation. Presented at Research!Louisville, University of Louisville, 2015.

Young, J.L., Wise, S.S., Xie, H., Wise, C.F., Fukuda, T., Guillette, Jr., L., and Wise, Sr., J.P. A comparison of the cytotoxic and genotoxic effects of hexavalent chromium in human, aquatic reptile and aquatic mammal skin cells. Presented at Research! Louisville, University of Louisville, 2015.

Speer, R.M., The, T., and Wise Sr., J.P. The Cytotoxicity and Genotoxicity of Particulate and Soluble Cobalt in Human Urothelial Cells. Presented at Research!Louisville, University of Louisville, 2015.

Wise, Sr., J.P. “When It Rains, It Pours- How Chromium Both Destabilizes Chromosomes and Impairs DNA Repair on Its Carcinogenic Path: Insights from Human and Whale Cells” Presented at the School of Medicine, University of Louisville, Louisville, Kentucky, 2015.

Wise, Sr., J.P. “The Toxicology of Chromium in Great Whales: Is Chromium the Next Global Pollutant?” Presented at the Eighth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, University of New Mexico, Alberquerque, New Mexico, 2014.

Wise, Sr., J.P. “The Potential Long-term Health Impacts of the Gulf of Mexico Oil Crisis: Insights from Whale Cells and Tissues.” Presented at the University of Coimbra, Coimbra, Portugal, 2014.

Wise, Sr., J.P. “The Gulf of Mexico Oil Crisis, an Unprecedented Marine Toxicology Experiment:  Insights from Whale Cells and Tissues.” Presented at the School of Marine Sciences, University of Maine, Orono, Maine, 2014.

Wise, Sr., J.P. “Prolonged Exposure to Particulate Chromate Induces a Switch from Homologous Recombination Repair to Non-Homologous End Joining Repair in Human Lung Cells” Presented in the Metals and DNA Repair Symposium at the Annual Meeting of the Society of Toxicology (SOT), 2014.

Wise, Sr., J.P. “Research Science Land and Sea:  Insights from Human and Whale Cells – Tales from a Portland High Graduate.” Presented at Portland High School, Portland, Maine, 2014.

Wise, C.F., Wise, J.T.F., Wise, S.S., Wise, Sr., J.P. The Cytotoxic and Genotoxic Impacts of Chemical Dispersants, Oil and Chemically Dispersed Oil on Sperm Whale Skin Cells. Proceedings of the Gulf of Mexico Oil Spill and Ecosystem Science Conference, p.50, 2014.

Wise, Sr., J.P., Qin, Q., Browning, C., Wise, S.S., Xie, H., and Holmes, A.L. Prolonged Exposure to Particulate Chromate Induces a Switch from Homologous Recombination Repair to Non-Homologous End Joining Repair in Human Lung Cells. Toxicological Sciences, 138: 1450, 2014.

Martino, J., Holmes, A.L., Xie, H., Nigg, E. and Wise, Sr., J.P. Particulate Hexavalent Chromium Causes Centrosome Separation by Activating the Kinase Nek2A. Toxicological Sciences, 138; 1272, 2014.

Wise, C.F., Wise, J., Wise, S.S., and Wise, Sr., J.P. Toxicity of Chemical Dispersants, Oil and Chemically Dispersed Oil in Sperm Whale Skin Cells. Toxicological Sciences, 138: 448, 2014.

Holmes, A., Smith, L.J., Wise, S.S., Mason, M., Zheng, T., and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Soluble and Particulate Cobalt in Human Lung Fibroblasts. Toxicological Sciences, 138: 1276, 2014.

Browning, C.L., Xie, H., Qin, Q., Masson, J.Y., and Wise, Sr., J.P. Prolonged Exposure to Particulate Chromate Inhibits Homologous Recombination Repair Proteins. Toxicological Sciences, 138: 1924, 2014.

Xie, H.,  Şekeroğlu V., Şekeroğlu Z., Falank C., Holmes A. L. and Wise, Sr., J.P. Depleted Uranium Induces DNA Damage and Alteration of DNA Repair Proteins in Human Lung Epithelial Cells. Toxicological Sciences, 138: 1942, 2014.

Stewart J., Nutter N., Wise, Sr., J.P. and Xie H. Synergistic Effect of Arsenic on Hexavalent Chromium Cytotoxicity and Genotoxicity in Human Lung Cells. Toxicological Sciences, 138: 1320, 2014.

Wise, S.S., Xie, H., Wise, Jr., J.P., Wise, C.F., Guillette, Jr., L.J., and Wise, Sr., J.P. Comparative Toxicity of Hexavalent Chromium (Cr(VI)) in Human and Alligator Cells. Toxicological Sciences, 138: 1279, 2014.

Savery, L.C., Wise, J.T.F., Wise, S.S., Falank, C., Gianios, Jr., C., Thompson, W.D., Perkins, C., Zheng, T., Zhu, C., and Wise, Sr., J.P. Global Assessment of Arsenic Pollution Using Sperm Whales (Physeter macrocephalus) As an Indicator Species. Toxicological Sciences, 138: 1303, 2014.

Browning, C.L., Xie, H. and Wise Sr., J.P. Chronic Particulate Chromate Exposure Inhibits the Nuclear Transport of RAD51. Presented at the Maine Biological and Medical Sciences Symposium, 2014.

Wise, S.S., Xie, H., Smith, A., Fukuda, T. and Wise, Sr., J.P. The Cytotoxic and Genotoxic Effects of Hexavalent Chromium in Sea Turtle Cells. 34th Annual Symposium on Sea Turtle Biology and Conservation, 2014.

Martino, J., Holmes, A.L., Xie, H., Thompson, W.D. and Wise, Sr., J.P. Centrosome Defects in Metal Carcinogenesis: Effects of Particulate Cr(VI) on Centrosome Separation, Nek2 and Eg5. Annual Bamaplooza meeting, 2014.

Wise, S.S., Martino, J., Smith, A. and Wise, Sr., J.P. Role of Centrosome Number in Chemical Carcinogenesis: Particulate Hexavalent Chromium Induces a Permanent Heritable Phenotype of Centrosome Amplification & Chromosome Instability in Human Lung Cells. Proceedings of Centrosomes and Spindle Pole Bodies conference, p. 177, 2014.

Wise, Sr., J.P., Holmes, A.L., Martino, J. and Wise, S.S. Centrosome Abnormalities in Chemical Carcinogenesis: Centrosome Amplification and Separation Defects Are Early Events after Exposure to Carcinogenic Particulate Hexavalent Chromium. Proceedings of Centrosomes and Spindle Pole Bodies conference, p. 178, 2014.

Wise, Sr., J.P., Wise, Jr., J.P., Wise, J.T.F., Wise, C.F., Wise, S.S., Martino, J. and Li Chen, T. The Toxicology of Chromium in Great Whales: Is Chromium the Next Global Pollutant? Proceedings of the Eighth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, 22, 2014.

Wise, S.S., Martino, J., Xie, H., Thompson, W.D. and Wise, Sr., J.P. Chromosome Instability and DNA Repair Deficiency are Permanent, Heritable Phenotypes after Particulate Hexavalent Chromium Exposure. Presented at the Eighth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, 26, 2014.

Xie, H., Wise, Sr., J.P., Stewart, J., Yang, L. and Nutter, N. Mechanism of Arsenic Synergistic Effect on Hexavalent Chromium-induced Metaphase Damage in Human Lung Cells Presented at the Eighth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, 2014.

Thompson, K.N., Qui, Q., Hong, X. and Wise, Sr., J.P. Investigating the Effect of Hexavalent Chromium on an Error-Prone Repair Pathway, Non-Homologous End Joining. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Nutter, N., Wise, Sr., J.P. and Xie, H., Chromium (VI) and Arsenic Co-exposure Induced Transformation in Human Lung Epithelial Cells. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Stewart, J., Nutter, N., Wise, Sr., J.P. and Xie, H. Genotoxicity of Hexavalent Chromium and Arsenic Co-Treatment in Human Lung Fibroblasts. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Wise, C.F., Wise, S.S., Xie, H., Wise, Jr., J.P., Gillette, Jr., L.J. and Wise, Sr., J.P. Comparative Toxicity of Hexavalent Chromium (Cr(VI)) in Human and Alligator Cells. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Raph, S., Wise, S. and Wise, Sr. J.P. Homologous Recombination Is Required to Protect against Cobalt Induced Chromosomal Instability (CIN). Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Browning, C.L., Xie, H. and Wise, Sr., J.P. Prolonged Exposure to Particulate Chromate Inhibits the Nuclear Transport of Rad51. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Martino, J., Holmes, A., Xie, H. and Wise, Sr., J.P. Investigating the Mechanisms of Chromium(VI) Carcinogenesis: Effects on the Centrosome and the Nek2 and Eg5 Kinases. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Sassman, M.L., Wise, S.S. and Wise, Sr., J.P.  Chromium and Nickel Interaction in Sperm Whale Skin Cells. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Falank, C. and Wise, Sr., J.P.  Investigating Particulate Hexavalent Chromium-Induced Carcinogenesis through a Sister Chromatid Cohesion Mechanism. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Braun, M., Holmes, A.L, Hebert, M., and Wise, Sr., J.P.  Determining a Good Urothelial Cell Line to Study Arsenic-Induced Bladder Carcinogenesis. Proceedings of the University of Southern Maine’s 11th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2014.

Browning, C.L., Xie, H. and Wise Sr., J.P. Prolonged Exposure to Particulate Chromate Induces the Cytoplasmic Accumulation of RAD51. Presented at the Annual Meeting of the Graduate School of Biomedical Science and Engineering, University of Maine, 2014.

Wise, Sr., J.P. “When It Rains, It Pours- How Chromium Destabilizes Chromosomes and Impairs DNA Repair on Its Path to Carcinogenesis: Insights from Human and Whale Cells.” Presented at the Virginia Tech Carilion Research Institute, Roanoke, Virginia, 2013.

Wise, Sr., J.P. “Insights into the Mechanism of Chromium Carcinogenesis:  Leveraging Lessons Learned into a Project to Study the Carcinogenic Interaction of Particulate Nickel and Cobalt in Human Lung Cells.” Presented at Lanzhou University, Lanzhou, China, 2013.

Wise, Sr., J.P. “Of Whales and Men:  Elucidating a Comprehensive Carcinogenic Mechanism for Chromium, a Global Environmental Pollutant” Presented at the Duke Nicholas School of the Environment and the Duke Cancer Institute, 2013.

Wise, Sr., J.P. “Particulate Chromate Alters the Localization of Proteins that Protect Cells against Chromosome Instability.” Presented at the Toxicology 2013 Annual Meeting, 2013.

Wise, Sr., J.P. Public Presentation on Wise Laboratory Marine Research in Vieques. Vieques Conservation and Historical Trust, Vieques, Puerto Rico, 2013.

Wise, Sr., J.P., Wise, Jr., J.P., Wise, J., Perkins, C. and Thompson, W.D. Is Exposure to Genotoxic Metals Part of the Toxic Legacy of the Deepwater Horizon Oil Crisis? Proceedings of the Gulf of Mexico Oil Spill and Ecosystem Science Conference, p.30, 2013.

Wise, Sr., J.P. and Griffit, J. The Toxicological Impact of Metals, Crude Oil, and Chemical Dispersants from the Gulf of Mexico Oil Crisis on Human and Wildlife Health. Proceedings of the annual meeting of the American Association for the Advancement of Science (AAAS), 72, 2013.

Kerr, I and Wise, Sr., J.P. The Deepwater Horizon Disaster. Proceedings of the annual meeting of the American Association for the Advancement of Science (AAAS), 73, 2013.

Wise, Sr., J.P., Kerr, I, Wise, Jr., J.P., Wise, C.F., Wise, S.S., Wise, J., Gianios, Jr., C., Wallace, B., Huang, S., LaCerte, C. and Holmes, A.L. Voyage 2 of the Odyssey: The Impact of the Oil Crisis on Health Using Whales As An Indicator Species. Proceedings of the annual meeting of the American Association for the Advancement of Science (AAAS), 73, 2013.

Qin, Q., Wise, S.S., Xie, H., Holmes, A.L. and Wise, Sr., J.P. Chronic Particulate Chromate Exposure Induces Persistent DNA Double Strand Breaks and Suppresses Rad51 Response in Human Lung Cells. Proceedings of the Keystone Symposia on Genomic Instability and DNA Repair, 201, 2013.

Wise, S.S., Holmes, A.L., Xie, H., Thompson, W.D. and Wise, Sr., J.P. Repeated Particulate Chromate Exposure Induces a Permanent Phenotypic Change of Genomic Instability, DNA Double Strand Break Repair Deficiency and Neoplastic Transformation in Human Lung Cells. Proceedings of the Keystone Symposia on Genomic Instability and DNA Repair, 201, 2013.

Braun, M., Sacco, J., Lechner, J. and Wise, Sr., J.P. E162 Protects Against Chromium (VI)-Induced Cytotoxicity and Genotoxicity in Human Lung Fibroblast Cells. Toxicological Sciences, 132: 250, 2013.

Holmes, A.L., Hebert, M., Case, C.P. and Wise, Sr., J.P. Development of an Immortalized Urothelial Cell Line to Study Metal-Induced Bladder Carcinogenesis. Toxicological Sciences, 132: 254, 2013.

Wise, J., Wise, S.S., Xie, H., Griffitt, J. and Wise, Sr., J.P. Chemical Dispersants Used in the Gulf of Mexico Are Cytotoxic to Human Lung and Skin Fibroblasts. Toxicological Sciences, 132: 32, 2013.

Falank, C., and Wise, Sr., J.P. Chronic Exposure to Particulate Hexavalent Chromium Disrupts Shugoshin1 Localization in Human Lung Cells. Toxicological Sciences, 132: 123, 2013.

Wise, Jr., J.P., Wise, J., Thompson, W.D., Perkins, C. and Wise, Sr., J.P. Is Genotoxic Metal Exposure Part of the Toxic Legacy of the Deepwater Horizon Oil Crisis? Toxicological Sciences, 132: 330, 2013.

Wise, S.S., Holmes, A.L., Xie, H., Thompson, W.D. and Wise, Sr., J.P. Repeated Particulate Chromate Exposure Induces Chromosome Instability, a DNA Double Strand Break Repair-Deficient Phenotype, and Neoplastic Transformation in Human Lung Cells. Toxicological Sciences, 132: 250, 2013.

Wise, C.F., Wise, S.S., Holmes, A. and Wise, Sr., J.P. Fin Whale Cells Are More Resistant to Particulate Chromate Cytotoxicity than Human Cells. Toxicological Sciences, 132: 251, 2013.

Qin, Q., Xie, H., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Chronic Exposure to Particulate Chromate Induces Persistent DNA Double Strand Breaks in Human Lung Cells. Toxicological Sciences, 132: 250, 2013.

Savery, L.C., Holmes, A.L., Braun M.C., Evers, D.C., Kerr I., Payne R., Thompson W.D., Perkins, C., Zheng, T., Zhu, C. and Wise, Sr., J.P. Selenium Protects Against the Toxic Effects of Methylmercury in Sperm Whale (Physeter macrocephalus) Skin Cells. Toxicological Sciences, 132: 328, 2013.

Browning, C.L., Xie, H., Qin, Q. and Wise Sr., J.P. Investigating the Mechanism of Particulate Cr(VI)-induced Homologous Recombination Repair Deficiency. Presented at the Maine Biological and Medical Sciences Symposium, 2013.

Wise, C.F., Wise, S.S., Wise, Sr., J.P. Toxicity of chemical dispersants, oil and chemically dispersed oil in sperm whale skin cells (Physeter macrocephalus). Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 44: 143, 2013.

Wise, Jr., J.P., Wise, J.T.F., Thompson, W.D., Perkins, C. and Wise, Sr., J.P. Is Genotoxic Metal Exposure Part of the Toxic Legacy of the Deepwater Horizon Oil Crisis? Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 44: 147, 2013.

The, T., Holmes, A.L. and Wise, Sr., J.P. Chronic Exposure to Particulate Nickel Induces Neoplastic Transformation in Human Lung Epithelial Cells. Environmental and Molecular Mutagenesis 52: P41, 2013.

Hernandez-Ramon, E.E., Wise, Sr., J.P., Si, N., Wise, S.S., Wise, Jr., J.P. and Poirier, M.C. Detection of polycyclic aromatic hydrocarbon (PAH)-DNA adducts in epidermis from sperm whales (Physeter macrocephalus) in the Gulf of Mexico. Environmental and Molecular Mutagenesis 52: P87, 2013.

Wise, S.S., Holmes, A.L., Xie, H., Martino, J., Raph, S., Thompson, W.D. and Wise, Sr., J.P. Hexavalent Chromium Impairs DNA Repair Resulting in Mitotic Disruption and Chromosome Instability. Environmental and Molecular Mutagenesis 52: P21, 2013.

Wise, Sr., J.P., Xie, H., Holmes, A.L., Falank, C., Karri, N.D. and Wise, S.S. Particulate Chromate Alters the Localization of Proteins that Protect Cells against Chromosome Instability. Journal of Clinical Toxicology 3: 35, 2013.

Wise, S.S., Holmes, A.L., Xie, H., Martino, J., Raph, S., Thompson, W.D. and Wise, Sr., J.P. Chromosome Instability Induced by Hexavalent Chromium is a Result of Impaired DNA Repair and Mitotic Disruption. Journal of Clinical Toxicology 3: 36, 2013.

Şekeroğlu, Z.A., Holmes, A.L. and Wise, Sr., J.P. Exposure to Particulate Chromate Induces Cytotoxicity and Chromosome Instability in Human Bladder Cells. Proceedings of the 1^st International Cell Death Research Congress, 117, 2013.

Şekeroğlu, V., Xie, H., Holmes, A.L., and Wise, Sr., J.P. Depleted Uranium Induces DNA Double Strand Breaks and Cell Death in Human Lung Epithelial Cells. Proceedings of the 1^st International Cell Death Research Congress, 117, 2013.

Martino, J., Holmes, A.L. and Wise, Sr., J.P. Investigating the Effects of Particulate Hexavalent Chromium on the Centrosome Cycle in Human Lung Cells. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Raph, S., Xie, H. and Wise, Sr., J.P. Hexavalent Chromium Exposure Decreases Mad1 and Mad2 Localization and Interaction in Human Lung Fibroblasts. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Smith, L.J., Holmes, A.L. and Wise, Sr., J.P. Chronic Exposure of Cobalt Induces Cytotoxicity and Genotoxicity in Human Lung Cells. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Thompson, K., Wise, S.S. and Wise, Sr., J.P. Investigating if Large Whale Species and Humans have differential rates of DNA Double Strand Break Repair. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Stewart, J., Xie, H. and Wise, Sr., J.P. Arsenic and Hexavalent Chromium Co-treatment Toxicity in Human Lung Cells. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Wise, J., Wise, S.S., Xie, H., Griffitt, J. and Wise, Sr., J.P. Chemical Dispersants Used in the Gulf of Mexico Are Cytotoxic to Human Lung and Skin Fibroblasts. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Falank, C. and Wise, Sr., J.P. Chronic Exposure to Particulate Hexavalent Chromium Disrupts Shugoshin1 Localization in Human Lung Cells. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Braun, M., Sacco, J., Lechner, J. and Wise, Sr., J.P. E162 Protects Against Chromium (VI)-Induced Cytotoxicity and Genotoxicity in Human Lung Fibroblast Cells. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Smith, A., Martino, J., Wise, S.S., Holmes, A.L. and Wise, Sr., J.P. Lead Chromate Induces Persistent Centrosome Amplification in Human Lung Cells. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Keim, E., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Nickel Compounds Are Cytotoxic and Genotoxic to Sperm Whale Skin Fibroblasts. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Sassman, M.L., Wise, S.S. and Wise, Sr., J.P.  A Comparison of DNA Double Strand Break Repair between Sperm Whales Individuals and Humans. Proceedings of the University of Southern Maine’s 10th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2013.

Wise, Sr., J.P. “The Gulf of Mexico Offshore Toxicology Study”, in The Toxicological Impact of the Gulf of Mexico Oil Spill on Human and Wildlife Health Symposium, Annual Meeting of the American Association for the Advancement of Science (AAAS), Boston, Massachusetts. Talk recommended to AAAS by the Society of Toxicology to represent the quality of science at Society of Toxicology, 2012.

Wise, Sr., J.P. “Mechanisms of Particulate Chromate-Induced Chromosome Instability”, University of Kentucky, Lexington, Kentucky, 2012.

Wise, Sr., J.P., Discussion on Silent Spring Revisited: 50 Years Later, Portland Public Library, Portland, Maine, 2012.

Wise, Sr., J.P., Public Presentation on Oil Toxicology in Whales, Curtis Library, Brunswick, Maine, 2012.

Wise, Sr., J.P., Public Presentation on Wise Laboratory Marine Research in Vieques. Vieques Conservation and Historical Trust, Vieques, Puerto Rico, 2012

Wise, Sr., J.P. “The Gulf of Mexico Offshore Toxicology Study”, in The Toxicological Impact of the Gulf of Mexico Oil Spill on Human and Wildlife Health Symposium, Annual Meeting of the Society of Toxicology, San Francisco, California,, 2012.

Wise, Sr., J.P. and Griffit, J. The Toxicological Impact of Metals, Crude Oil, and Chemical Dispersants from the Gulf of Mexico Oil Crisis on Human and Wildlife Health. Toxicological Sciences, 126: 379, 2012.

Wise, S.S., Holmes, A.L., Xie, H. Martin, S., Thompson, W.D. and Wise, Sr., J.P. Hexavalent chromium induces chromosome instability resulting in a DNA double strand break repair deficient phenotype and neoplastic transformation. Toxicological Sciences, 126: 540, 2012.

McKay, J.M., Holmes, A.L., Case, C.P. and Wise, Sr., J.P. Chronic Exposure to Hexavalent Chromium Induces Chromosome Instability in Primary Human Urothelial Cells. Toxicological Sciences, 126: 533, 2012.

LaCerte, C., Wise, S.S. and Wise, Sr., J.P. Particulate hexavalent chromate induces a permanent phenotypic change in human lung fibroblast cells after chronic exposure. Toxicological Sciences, 126s: 2800, 2012.

Kerr, I and Wise, Sr., J.P. The Deepwater Horizon Disaster. Toxicological Sciences, 126: 379, 2012.

Karri, N.P. and Wise, Sr., J.P. Role of a Spindle Assembly Checkpoint Protein, Cdc20, in Chromate-Induced Spindle Assembly Checkpoint Bypass. Toxicological Sciences, 126: 539, 2012.

Wise, Jr., J.P. Huang, S., Wheeler C. and Wise, Sr., J.P. Effects of Altered Gravity on Chromium-Induced Genotoxicity in Human Lung Cells. Toxicological Sciences, 126: 540, 2012.

Falank, L., Xie, H., McGovern, D., Sample, A. Abramson, S., Perez, A., Mason, M.D., Craig, G. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Lung Cells. Toxicological Sciences, 126: 277, 2012.

Xie, H., Martin, S., Huang, S. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Arsenic in Primary Human Lung Cells. Toxicological Sciences, 126: 314, 2012.

Holmes, A.L. and Wise, Sr., J.P. Arsenic is Clastogenic and Aneugenic to Primary Human Urothelial Cells. Toxicological Sciences, 126: 383, 2012.

Duffy, R., Holmes, A.L. and Wise, Sr., J.P. Elucidating the role of Nek2A in zinc chromate-induced centrosome amplification and aneuploidy in human lung fibroblasts. Toxicological Sciences, 126: 533-534, 2012.

Wise, C.F., Wise, S.S. and Wise, Sr., J.P. Fin Whale Cells Are More Resistant to Hexavalent Chromium than Human Cells. Toxicological Sciences, 126: 583, 2012.

Braun, M., McKay, J.M., Wheeler C. and Wise, Sr., J.P. Simulated Microgravity Decreases Chromium (VI)-Induced Genotoxicity in Human Skin Fibroblast Cells. Toxicological Sciences, 126: 540, 2012.

Wise, J., Wise, S.S. Xie, H., Griffit, J. and Wise, Sr., J.P. Are Chemical Dispersants Used in the Gulf of Mexico Cytotoxic and Genotoxic to Human Lung and Skin Fibroblasts? Toxicological Sciences, 126: 580, 2012.

Wise, Sr., J.P., Kerr, I, Wise, Jr., J.P., Wise, C.F., Wise, S.S., Wise, J., Gianios, Jr., C., Wallace, B., Huang, S., LaCerte, C. and Holmes, A.L. Voyage 2 of the Odyssey: The Impact of the Oil Crisis on Health Using Whales As An Indicator Species. Toxicological Sciences, 126: 380, 2012.

Wise, S.S., Holmes, A.L., Xie, H., Martin, S., Thompson, W.D. and Wise, Sr., J.P. Hexavalent chromium induces chromosome instability leading to DNA double strand break repair deficiency and neoplastic transformation. Proceedings of the American Association for Cancer Research, 52: 750-751, 2012.

Xie, H., Martin, S., Wise, Sr., J.P. and Huang, S. Genotoxicity of Arsenic in Primary Human Bronchial Cells. Proceedings of the American Association for Cancer Research, 52: LB-393, 2012.

Qin, Q., Xie, H., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Particulate Chromate Induces Persistent DNA Double Strand Breaks Resulting in Disruption of Homologous Recombination Repair in Human Lung Cells. Proceedings of the American Association for Cancer Research, 52: 514, 2012.

Wise, C.F., Wise, S.S. and Wise, Sr., J.P. Chemical Dispersants Used in The Gulf of Mexico Are Cytotoxic to Sperm Whale Skin Fibroblasts. Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 43: 152, 2012.

Wise, Jr., J.P., Wise, C.F., Keim, E. and Wise, Sr., J.P. Comparison of Observed Nickel Levels and Nickel Toxicity in Whales. Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 43: 153, 2012.

Wise, J., Wise, S.S., Xie, H., Griffitt, J. and Wise, Sr., J.P. Chemical Dispersants Used in the Gulf of Mexico Oil Crisis Response Are Cytotoxic to Human Skin Fibroblasts. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 200, 2012.

Falank, Jr., L.F., Wise, C.F. and Wise, Sr., J.P. Chemical Dispersants Are Cytotoxic to Humpback Whale and Sperm Whale Skin Cells. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 401, 2012.

Browning, C.L., Holmes, A.L., Mason, M., Kandpal, S. and Wise Sr., J.P. Assessing the Toxicity of an Emerging Environmental Pollutant: Titanium Dioxide Nanoparticles. Presented at the Maine Biological and Medical Sciences Symposium, 2012.

Duffy, R., Holmes, A. and Wise, Sr., J.P. Elucidating the Role of Nek2A in Zinc Chromate-Induced Centrosome Amplification and Aneuploidy in Human Lung Fibroblasts. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Karri, N.D. and Wise, Sr., J.P. Role of a Spindle Assembly Checkpoint Protein, Cdc20, in Chromate-Induced Spindle Assembly Checkpoint Bypass. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Joyce, K., LaCerte, C. and Wise, Sr., J.P. Particulate Depleted Uranium Induces Chromosome Hypercondensation in Human Bronchial Epithelial Cells. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

LaCerte, C. and Wise, Sr., J.P. Hexavalent Chromium Exposure Decreases Shugoshin1 Localization in Human Lung Fibroblasts. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Qin, Q., Xie, H., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Particulate Chromate Induces Persistent DNA Double Strand Breaks Resulting in Disruption of Homologous Recombination Repair in Human Lung Cells. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Smith, L.J., Holmes, A.L. and Wise, Sr., J.P. Chronic Exposure of Cobalt Induces Cytotoxicity and Potential Genotoxicity in Human Lung Cells. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Wise, S.S, Holmes, A.L., Xie, H., Thompson, W.D. and Wise, Sr., J.P. Hexavalent Chromium Induces Chromosome Instability Resulting in a DNA Double Strand Break Repair Deficient Phenotype and Neoplastic Transformation. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Li Chen, T., Wise, S.S., Xie, H. and Wise, Sr., J.P. Hexavalent Chromium Induces DNA-Double Strand Breaks in North Atlantic Right Whale and Sperm Whale Cells. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Martino, J., Wise, S.S., Perkins, C., Kerr, I., Rowntree, V., Sironi, M. and Wise, Sr., J.P. Metal Levels in Southern Right Whale Skin Biopsies. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Wise, J., Wise, S.S., Xie, H. and Wise, Sr., J.P. Using Nutraceuticals to Prevent Organic Chemical Toxicity. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Sacco, J., Braun, M., Falank, L. and Wise, Sr., J.P. Nutraceuticals Protect Against Particulate Ni(II)-Induced Cytotoxicity to Human Lung Fibroblast Cells. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Browning, C.L., Holmes, A.L., Mason, M., Kandpal, S. and Wise, Sr., J.P. Assessing the Toxicity of an Emerging Environmental Pollutant: Titanium Dioxide Nanoparticles. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Wise, C.F., Wise, S.S. and Wise, Sr., J.P. Chemical Dispersants Used in the Gulf of Mexico Are Cytotoxic to Sperm Whale Skin Fibroblasts. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Wise, Jr., J.P., Wise, C.F., Keim, E. and Wise, Sr., J.P. Comparison of Observed Nickel Levels and Nickel Toxicity in Whales. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Braun, M., Sacco, J., Falank, L. and Wise, Sr., J.P. Nutraceuticals Protect Against Chromium(VI)-Induced Cytotoxicity and Genotoxicity in Human Lung Fibroblast Cells. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Keim, E., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Nickel Compounds on Marine Mammal and Human Fibroblasts. Proceedings of the University of Southern Maine’s 9th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2012.

Browning, C.L., Holmes, A.L., Mason, M., Kandpal, S. and Wise Sr., J.P. The Toxicity of an Emerging Environmental Pollutant: Titanium Dioxide Nanoparticles. Presented at the Annual Meeting of the Graduate School of Biomedical Science, University of Maine, 2012.

Wise, Sr., J.P. “Voyage 2 of the Odyssey: the Impact of the Oil Crisis on Health Using Whales as an Indicator Species”, Annual meeting of the Environmental Mutagen Society, Quebec, Canada, 2011.

Wise, Sr., J.P. “Lessons about Global Pollution and Human Health Learned from Whales: The Gulf of Mexico Oil Crisis”, University of Maine, Farmington, Farmington, Maine, 2011.

Wise, Sr., J.P. “Water Quality/Oil Spill”, presented in “Protecting You and Your Pet through the Science of Toxicology: Paracelsus Goes to Washington.” Marion E. Koshland Science Museum of the National Academy of Science, Washington, D.C., 2011.

Savery, L.C., Eagle, S., Stapleton, H.M., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Global Assessment of Polybrominated Diphenyl Ethers in Sperm Whale (Physeter Macrocephalus) Skin. Program of the National Council for Science and the Environment’s (NCSE) 11th National Conference on Science, Policy, and the Environment, 50, 2011.

Wise Sr., J.P., Wise, S.S., LaCerte, C., Li Chen, T., Wise, J., Gianios Jr., C., Payne, R., Kerr, I. and Thompson, W. D. Chromium Is a Global Concern for Sperm Whales (Physeter macrocephalus). Program of the National Council for Science and the Environment’s (NCSE) 11th National Conference on Science, Policy, and the Environment, 49, 2011.

Wise, S.S., Wise, Jr., J.P., Braun, M., Wise, C.F., Wise, J., Gianios Jr., C., Huang, S., Wallace, B., Glass, I., Walker, R., LaCerte, C., McKay, J., Kerr, I., Payne, R. and Wise Sr., J.P. Assessing the Impact of the Deepwater Horizon Oil Spill on Whales. Program of the National Council for Science and the Environment’s (NCSE) 11th National Conference on Science, Policy, and the Environment, p.49, 2011.

Wise, S.S., Holmes, A.L., Xie, H., Martin, S., Pelsue, S.C., Thompson, W.D. and Wise Sr., J.P. Hexavalent chromium induces chromosome instability resulting in a DNA double strand break repair deficient phenotype and neoplastic transformation. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 125, 2011.

Qin Q., Holmes, A.L., Xie, H., Wise, S.S. and Wise, Sr., J.P. Particulate Chromate Induces Chromosome Instability by Disrupting Normal DNA Double Strand Break Repair and Cell Cycle Regulation in Human Lung Cells. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 109, 2011.

Xie, H., LaCerte, C., Joyce, K. and Wise, Sr., J.P. Depleted Uranium Induces Chromosome Instability and Epigenetic Modification in Human Lung Epithelial Cells. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 126, 2011.

Braun, M., Qin, Q., Xie, H., Leighton, R., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Comparative Cytotoxicity of Simulated Moon and Mars Dusts, Earth Dust and Selected Lunar Dust Components in Human Lung Epithelial Cells. Toxicological Sciences, 120: 65, 2011.

LaCerte, C., Chen, T., Holmes, A., Wise, S., Kraus, S., Gulland, F.M.D. and Wise, Sr., J.P. Comparison of Chromium Toxicity on Human, Steller Sea Lion, Sperm Whale and Northern Right Whale Skin Cells. Toxicological Sciences, 120: 517, 2011.

Wise, C.F., Braun, M., Wise, Jr., J.P., Wise, J., Wise, S.S., Kerr, I., Xie, H. and Wise, Sr., J.P. Developing a Whale Cell Line at Sea to Evaluate the Cytotoxicity and Genotoxicity of Chemical Dispersants Used in the Gulf Of Mexico Oil Crisis. Toxicological Sciences, 120: 503, 2011.

Duffy, R., Wise, J., Xie, H., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Lunar Dust Simulant is Cytotoxic but Not Genotoxic to Human Skin Fibroblast Cells. Toxicological Sciences, 120: 64, 2011.

Holmes, A.L., Wise, S.S., Pelsue, S., Lingle, W., Salisbury, J. and Wise, Sr., J.P. Chronic Exposure to Particulate Chromate Induces Numerical Chromosome Instability and Centrosome Amplification in Human Lung Cells. Toxicological Sciences, 120: 59, 2011.

Xie, H., McGovern, D., Sample, A., Abramson, S., Perez, A., Falank, L., Mason, M.D., Graig, G. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Acute and Chronic Exposure to Silver Nanoparticles in Human Lung Cells. Toxicological Sciences, 120: 464, 2011.

Wise, J., Wise, S., Xie, H. and Wise, Sr., J.P. Chemical Dispersants Used in the Gulf of Mexico Are Cytotoxic and Genotoxic to Human Skin Fibroblasts. Toxicological Sciences, 120: 503, 2011.

Wise, Jr., J.P., Wheeler, C. and Wise, Sr., J.P. The Impact of Altered Gravity on Chromate Genotoxicity: Using a Bioreactor to Simulate Microgravity in Cell Culture. Toxicological Sciences, 120: 60, 2011.

Joyce, K., LaCerte, C. and Wise, Sr., J.P. Particulate Depleted Uranium Induces Selective X-Chromosome Fragmentation Dependent on XRCC3 in Chinese Hamster Ovary Cells. Toxicological Sciences, 120: 60, 2011.

Kerr, I. and Wise, Sr., J.P. The Voyages of the Odyssey: A Unique Platform for Toxicological Research and Education. Toxicological Sciences, 120: 400, 2011.

Martino, J., Wise, S.S., Holmes, A.L., Xie, H. and Wise, Sr., J.P. Bowhead Whale Lung Cells Are Resistant to Cr(IV)-Induced Genotoxicity. Toxicological Sciences, 120: 59, 201.

Wise, S.S., Kerr, I., Wise, Jr., J.P., Wise, C.F., Wise, J., Gianios, Jr., C., Braun, M., Wallace, B., Glass, I., Walker, R., LaCerte, C., McKay, J., Chen, T., Martino, J., Chapman, G., Duffy, R., Leighton, R., Joyce, K. and Wise, Sr., J.P. The Gulf Oil Crisis: Impact on Whales. Toxicological Sciences, 120: 514, 2011.

Chen, T., Martino, J., Wise, S.S., LaCerte, C., Shaffiey, F., Xie, H., Holmes, A.L., McPhearson, K., Kerr, I., Payne, R., Kraus, S.D. and Wise, Sr., J.P. The Toxic Effects of Chromium Compounds in North Atlantic Right Whale and Sperm Whale Cells. Toxicological Sciences, 120: 516, 2011.

Savery, L.C., Eagle, S., Stapleton, H.M., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Global Assessment of Polybrominated Diphenyl Ethers in Sperm Whale (Physeter Macrocephalus) Skin. Toxicological Sciences, 120: 403, 2011.

Wise, C.F., Wise, S.S. and Wise, Sr. J.P. Chemical Dispersants Used in the Gulf of Mexico Are Cytotoxic and Genotoxic to Sperm Whale Skin Fibroblasts. Presented at the 16th International Symposium on Pollutant Responses in Marine Organisms (PRIMO), 2011.

Wise, J., McKay, J.M., Lacerte, C., Walter, R.B. and Wise Sr., J.P. The Cytotoxicity and Genotoxicity of Hexavalent Chromium in Medaka Cells. Presented at the 16th International Symposium on Pollutant Responses in Marine Organisms (PRIMO), 2011.

Wise, Jr. J.P., Wise, S.S. and Wise, Sr., J.P. The Use of Sperm Whale Karyotype to Assess the Potential Impacts of the Gulf of Mexico Oil Spill. Presented at the 16th International Symposium on Pollutant Responses in Marine Organisms (PRIMO), 2011.

Wise, S.S., Kerr, I., Wise, Jr., J.P., Wise, C.F., Wise, J., Gianios Jr., C., Braun, M., Wallace, B., Walker, R., LaCerte, C., McKay, J.M. and Wise, Sr., J.P. The Impact of the Gulf Oil Crisis on Whales. Presented at the 16th International Symposium on Pollutant Responses in Marine Organisms (PRIMO), 2011.

Wise, Sr., J.P., Kerr, I., Wise, Jr., J.P., Wise, C.F., Wise, S.S., Wise, J., Gianios Jr., C., Wallace, B., Glass, I., Walker, R., LaCerte, C. and Holmes, A.L. Voyage 2 of the Odyssey: the Impact of the Oil Crisis on Health Using Whales as an Indicator Species. Environmental and Molecular Mutagenesis 52: S29, 2011.

Wise, Jr., J.P., Xie, H., Wallace, W., Jeevarajan, A., Jenniskens, P., Shaddad, M.H. and Wise, Sr., J.P. Toxicity of Simulated Martian and Lunar Dusts, Earth and Asteroidal Dust in Human Lung Cells. Proceedings of the annual meeting of the American Society for Gravitational and Space Biology, 80, 2011

Wise, Jr., J.P., Wise, S.S., Kerr, I. and Wise, Sr., J.P. Assessing the Potential Effects of the Gulf of Mexico Oil Disaster using Sperm Whale Karyotypes. Proceedings of the 19th Biennial Conference of the Biology of Marine Mammals, 315, 2011.

Savery, L., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Global Assessment of Mercury and Selenium Levels in Sperm Whale (Physeter Macrocephalus) Skin. Proceedings of the 19th Biennial Conference of the Biology of Marine Mammals, p.264, 2011.

Martino, J., Li Chen, T. and Wise Sr., J.P. Cytotoxicity and Genotoxicity of Chromium and Lead Compounds in Harbor Porpoise Lung Cells. Proceedings of the 19th Biennial Conference of the Biology of Marine Mammals, p.192, 2011.

Wise Sr., J.P., Wise, S.S., Kerr, I. and Thompson, W.D. The Gulf of Mexico Offshore Toxicology Study: Chromium and Nickel Levels in Sperm Whale (Physeter macrocephalus) and Bryde’s Whale (Brydei edeni) Skin Tissues. Proceedings of the 19th Biennial Conference of the Biology of Marine Mammals, p.315, 2011.

Gianios, Jr., C., Wise, Jr., J.P., Wise, C.F., Wise, S.S., Wallace, R., Glass, I., Walker, R., LaCerte, C., McKay, J., Braun, M., Wise, J., Kerr, I. and Wise, Sr., J.P. The Gulf of Mexico Offshore Toxicology Study: Marine Mammal and Other Sightings in the Two Summers Immediately Following the 2010 Gulf of Mexico Oil Crisis. Proceedings of the 19th Biennial Conference of the Biology of Marine Mammals, p.108, 2011.

Kerr, I., Payne, R. and Wise, Sr., J.P. The Research Vessel Odyssey: A Unique Platform for Marine Mammal Toxicological Research and Education. Proceedings of the 19th Biennial Conference of the Biology of Marine Mammals, p.156, 2011.

Payne, R., Savery, L.C., Eagle, S., Stapleton, H.M., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Polybrominated Diphenyl Ethers Levels in Free Ranging Sperm Whale (Physeter Macrocephalus) Skin Samples from Around the Globe. Proceedings of the 19th Biennial Conference of the Biology of Marine Mammals, p.232, 2011.

Holmes, A., Wise S., Pelsue S., Lingle, W., Salisbury, J. and Wise, Sr., J.P. Chronic Exposure to Particulate Chromate Induces Numerical Chromosome Instability and Centrosome Amplification in Human Lung Cells. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Wise, S., Kerr, I, Wise, Jr., J.P., Wise, C.F., Wise, J., Gianios, Jr., C., Braun, M., Wallace, R., Glass, I., Walker, R., LaCerte, C., McKay, J., Li Chen, T., Martino, J., Chapman, G., Duffy, R., Leighton, R., Joyce, K. and Wise, Sr., J.P. The Gulf Oil Crisis: Impact on Whales. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Wise, Jr., J.P., Wise, S.S. and Wise, Sr., J.P. The Use of Sperm Whale Karyotype to Assess the Potential Impacts of the Gulf of Mexico Oil Spill. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Wise, Jr., J.P., Wheeler, C. and Wise, Sr., J.P. The Impact of Altered Gravity on Chromate Genotoxicity: Using a Bioreactor to Simulate Microgravity in Cell Culture. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Shively, E., Wise, Jr., J.P., McKay, J. and Wise, Sr., J.P. The Effect of Hypergravity on Cr(VI)-induced Cytotoxicity and Genotoxicity. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

LaCerte, C., Li Chen, T., Holmes, A., Wise, S., Kraus, S., Gulland, F. and Wise, Sr., J.P. Comparison of Chromium Toxicity on Human, Steller Sea Lion, Sperm Whale and Northern Right Whale Skin Cells. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Wise, C.F., Kreps, D., Wise, S.S. and Wise, Sr., J.P. Using Natural Products to Prevent the Toxic Effects of Chemicals in Altered Gravity. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Wise, C.F., Braun, M., Wise, Jr., J.P., Wise, J., Wise, S., Kerr, I., Xie, H. and Wise, Sr., J.P. Developing a Whale Cell Line at Sea to Evaluate the Cytotoxicity and Genotoxicity of Chemical Dispersants Used in the Gulf of Mexico Oil Crisis. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Kreps, D., Wise. C., Wise, S.S. and Wise, Sr., J.P. Using Blueberry Extract to Prevent Arsenic Toxicity. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Kari, N., Holmes, A. and Wise, Sr., J.P. Role of Cdc20 Spindle Assembly Checkpoint Protein in Chromate-Induced Spindle Assembly Checkpoint Bypass. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Martino, J., Wise, S., Holmes, A., Xie, H. and Wise, Sr., J.P. Hexavalent Chromium Genotoxicity in Human and Bowhead Whale Lung Cells. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Qin, Q., Holmes, A., Xie, H., Wise, S.S. and Wise, Sr., J.P. Particulate Chromate Induces Chromosome Instability by Disrupting Normal DNA Double Strand Break Repair and Cell Cycle Regulation in Human Lung Cells. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Li Chen, T., Martino, J., Wise, S., LaCerte, C., Shaffiey, F., Xie, H., Holmes, A., McPhearson, K., Kerr, I., Payne, R., Kraus, S. and Wise, Sr., J.P. The Toxic Effects of Chromium Compounds in North Atlantic Right Whale and Sperm Whale Cells. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Wise, J., Wise, S., Xie, H. and Wise, Sr., J.P. Using Nutraceuticals to Prevent Organic Chemical Toxicity. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Wise, J., Wise, S., Xie, H., Griffit, J. and Wise, Sr., J.P. Chemical Dispersants Used in the Gulf of Mexico Are Cytotoxic and Genotoxic to Human Skin Fibroblasts. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Lake, G., Xie, H., LaCerte, C., Martino, J., Leighton, R., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Toxicity of Lunar Dust Simulant and Lunar Dust Components on Human Brain Cells. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Duffy, R., Wise, J., Xie, H., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Lunar Dust Simulant is Cytotoxic but Not Genotoxic to Human Skin Fibroblast Cells. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Merrill, N., McKay, J. and Wise, Sr., J.P. Does Elderberry Syrup Help Protect Human Lung Cells From Chromate-Induced Toxicity? Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Braun, M., Leighton, R., Xie, H., Bickford, M., Lake, F., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Comparative Cytotoxicity and Genotoxicity of Mars, Earth and Moon Dusts in Human Skin Epithelial Cells. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Braun, M., Wheeler, C., Shehata, T. and Wise, Sr., J.P. Using Microcarriers and a Bioreactor to Support Cell Growth in a Simulated Microgravity Environment. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Joyce. K., LaCerte, C. and Wise, Sr., J.P. Particulate Depleted Uranium Induces Selective X-Chromosome Fragmentation in Chinese Hamster Ovary Cells Dependent on XRCC3. Proceedings of the University of Southern Maine’s 8th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2011.

Browning, C.L., Xie, H., Mason, M., Shively, B. and Wise Sr., J.P. Assessing the Cytotoxicity of Titanium Dioxide Nanoparticles. Presented at the Annual Meeting of the Graduate School of Biomedical Science and Engineering, University of Maine, 2011.

Wise, Sr., J.P., Public Presentation on Metal Toxicology in Bowhead Whales, Nantucket Historical Association, Nantucket, Massachusetts, 2011.

Wise, Sr., J.P. “DNA Damage in Marine Species”, Annual meeting of the Environmental Mutagen Society, Fort Worth, Texas, 2010.

Wise, Sr., J.P. “A Voyage to Save Our Oceans, Gulf of Mexico Voyage 2010”, University of Southern Mississippi, Ocean Springs, Mississippi, 2010.

Wise, Sr., J.P. “Mechanism of Hexavalent Chromate-Induced Chromosome Instability and Centrosome Amplification”, Triennial meeting of the EMBO Workshop: Chromosome Segregation and Aneuploidy, Edinburgh, Scotland, 2010.

Wise, Sr., J.P. “Mechanisms of Particulate Chromate-Induced Chromosome Instability”, Maine Institute for Human Genetics and Health, Bangor, Maine, 2010.

Xie, H., LaCerte, C. and Wise, Sr., J.P. Study on Mechanism for Depleted Uranium-induced Transformation in Human Lung Epithelial Cells. Toxicological Sciences, 114: 2170, 2010.

Wise, J., Duffy, R., Xie, H., LaCerte, C., Mason, M., Jeevarajan, A., Wallace, W., Hammond. D., Shehata, T. and Wise, Sr., J.P. Comparative Toxicity of Lunar, Martian and Earth Dusts in Human Skin Fibroblast Cells. Toxicological Sciences, 114: 375, 2010.

Wise, Jr., J.P., Wise, S.S., Wise, J., Mckay, J., Browne, M., Joyce, K., Braun, M., Wise, C.F., Duffy, R., Estell, E., Brown, J., Gianios Jr., C., Mason, M., Shehata, T., Hammond, D. and Wise, Sr., J.P. Simulated Spaceflight Increases Chromate-Induced Genotoxicity. Toxicological Sciences, 114: 1125, 2010.

Duffy, R. Wise, J., Xie, H., LaCerte, C., Mason, M., Jeevarajan, A., Wallace, W., Hammond. D., Shehata, T. and Wise, Sr., J.P. Comparative Toxicity of Short-Term and Chronic Exposure to Lunar Dust and Its Component Particles in Human Skin Fibroblast Cells. Toxicological Sciences, 114: 292, 2010.

Wise, S.S, Xie, H., Holmes, A.L., Wise, C.F., Doering, A., McGovern, D., Sample, A., Stevenson, M., Merrill, N., Chen, T.L., Martino, J., Bickford, M., Goodwin, T.J., O’Hara, T. and Wise, Sr., J.P. Bowhead (Balaena mysticetus) Lung Cells are Resistant to Chromium-Induced Damage. Toxicological Sciences, 114: 1128, 2010.

Wise, S.S., Holmes, A.L., Xie, H., Pelsue, S., Thompson, W.D. and Wise, Sr., J.P. Repeated Particulate Chromate Exposure Induces Chromosome Instability and a DNA Double Strand Break Repair-Deficient Phenotype in Human Lung Cells. Proceedings of the American Association for Cancer Research, 51: 3467, 2010.

Holmes, A.L., Wise, S.S., Pelsue, S., Lingle, W., Salisbury, J., Gallagher, J. and Wise, Sr., J.P. Prolonged Exposure to Zinc Chromate Induces Numerical Chromosome Instability via Centrosome Amplification in Human Lung Cells. Proceedings of the American Association for Cancer Research, 51: 3473, 2010.

Xie, H., LaCerte, C. and Wise, Sr., J.P. Epigenetic Mechanism Is Involved in Depleted Uranium-induced Transformation in Human Lung Epithelial Cells. Proceedings of the American Association for Cancer Research, 51: 3464, 2010.

Savery, L.C., O’Brien, T.J., Holmes, A.L., Wise, Sr., J.P. and Patierno, S.R. Nucleotide Excision Repair Contributes to Hexavalent Chromium-Induced Double Strand Breaks and Chromosomal Damage. Proceedings of the American Association for Cancer Research, 51: 2978, 2010.

Braun, M., Leighton, R., Xie, H., Bickford, M., Lake, G., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Comparative Cytotoxicity and Genotoxicity of Mars, Earth, and Moon Dusts in Human Skin Epithelial Cells. Presented at 2nd Annual Northeast Undergraduate Research Development Symposium, University of New England, 2010.

Duffy, R., Wise, J., Xie, H., LaCerte, C., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Comparative Toxicity of Short-Term and Chronic Exposure to Lunar Dust and Its Component Particles in Human Skin Fibroblast Cells. Presented at 2nd Annual Northeast Undergraduate Research Development Symposium, University of New England, 2010.

Lake, G., Xie, H., LaCerte, C., Martino, J., Leighton, R., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Toxicity of Lunar Dust Simulant on Human Brain Cells. Presented at 2nd Annual Northeast Undergraduate Research Development Symposium, University of New England, 2010.

Wise, J., Duffy, R., Xie, H., LaCerte, C., Mason, M., Jeevarajan, A., Wallace, W. and Wise, Sr., J.P. Comparative Toxicity of Lunar, Martian and Earth Dusts in Human Skin Fibroblast Cells. Presented at 2nd Annual Northeast Undergraduate Research Development Symposium, University of New England, 2010.

Wise, Jr. J.P., Wise, S., Wise, J., Wise, C.F., McKay, J., Braun, M., Courtemanche, A., Joyce, K., Freedman, B., Browne, M., Estell, E., Brown, J., Gianios, Jr. C., Mason, M. and Wise, Sr., J.P. Altered Gravity Exacerbates Chromate-Induced Chromosome Damage in Human Lung Cells. Presented at 2nd Annual Northeast Undergraduate Research Development Symposium, University of New England, 2010.

Wise, Sr., J.P., Holmes, A.L, Wise, S.S., Lingle, W. and Salisbury, J. Mechanism of Hexavalent Chromium-Induced Chromosome Instability and Centrosome Amplification. Proceedings of the 8^th International Chromosome Segregation and Aneuploidy Workshop, 11, 2010.

Wise, S.S., Holmes, A.L, Xie, H., Pelsue, S., Thompson, W.D. and Wise, Sr., J.P. Repeated Acute Exposure to Particulate Chromate Disrupts Mitosis to Induce Numerical and Structural Chromosome Instability in Human Lung Cells. Proceedings of the 8^th International Chromosome Segregation and Aneuploidy Workshop, 38, 2010.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W., Salisbury, J. and Wise, Sr., J.P. Mechanism of Hexavalent Chromium-Induced Chromosome Instability and Centrosome Amplification. Proceedings of the 8^th International Chromosome Segregation and Aneuploidy Workshop, 54, 2010.

Ather, A., Ma, Y., Reynolds, J., Wise, Sr., J.P., Inzucchi, S. and Katz, D. L. Chromium Effects on Glucose Tolerance, Insulin Sensitivity and Vascular Function in People at Risk for Diabetes. Presented at the 70th Scientific Sessions of the American Diabetes Association, 2010.

Eagle, S.D., Stapleton, H.M., Kerr, I. and Wise, Sr., J.P. Geographic Variation in the Concentrations of Polybrominated Diphenyl Ethers (PBDEs) and Methoyxlated PBDEs in Sperm Whale (Physeter macrocephalus) Blubber. Presented at the 30th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2010), 2010.

Holmes, A.L., Wise, S.S., Pelsue, S., Lingle, W., Salisbury, J. and Wise, Sr., J.P. Zinc Chromate Induces Chromosome Instability and Centrosome Amplification in Human Lung Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 2, 2010.

Xie, H., McGovern, D., Sample, A., Abramson, S., Perez, A., Mason, M.D., Craig, G. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Lung Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 13, 2010.

Wise, J., Wise, S.S., Xie, H. and Wise, Sr., J.P. Chemical Dispersants in the Gulf of Mexico Are Cytotoxic and Genotoxic to Human Skin Fibroblasts. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 16, 2010.

Wise, Sr., J.P., Wise, S.S., Holmes, A.L., LaCerte, C., Li Chen, T., Martino, J. and Wise Jr., JP. DNA Damage in Marine species. Environmental and Molecular Mutagenesis, 51(7): 702, 2010.

Wise, Sr., J.P., Kerr, I., Wise, Jr., J.P., Wise, C.F., Wise, J., Wise, S.S., Gianios, Jr., C., Braun, M., Martino, J., Chen, T., LaCerte, C., Duffy, R. and Joyce, K. The Impact of the Gulf Oil Crisis on Cetaceans: Establishing a Baseline of Toxicology Data for Sperm Whales and Bryde’s Whales in the Gulf of Mexico. Presented at the Collaborative Scientific Research in Relation to the Gulf Oil Spill, 2010.

Wise, Sr., J.P., Kerr, I., Wise, Jr., J.P., Wise, C.F., Wise, J., Wise, S.S., Gianios, Jr., C., Braun, M., Davenport, J., Chapman, G., Duffy, R., Leighton, R., Martino, J., Chen, T., LaCerte, C., Joyce, K. And Wray, G. The Impact of the Gulf Oil Crisis on Whales: Establishing a Baseline of Toxicology Data in the Gulf. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 381, 2010.

Wise, Jr., J.P., Braun, M., Wise, C.F., Wise, J., Wise, S.S., Gianios, Jr., C., LaCerte, C., Chen, T., Huang, S., Martino, J., Holmes, A.L., McKay, J., Joyce, K. and Wise, Sr., J.P. Voyage II of the Odyssey: An expedition to study whales in the Gulf of Mexico in response to the Gulf oil crisis. Presented at the 2^nd Annual Civic Matters Conference, 2010.

Holmes, A.L., Wise, S.S., Pelsue, S., Lingle, W., Salisbury, J. and Wise, Sr., J.P. Mechanism of Particulate Chromate-Induced Chromosome Instability in Human Lung Cells. Presented at the 6th Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, 2010.

Xie, H., LaCerte, C. and Wise, Sr., J.P. Mechanism of Depleted Uranium-induced Neoplastic Transformation in Human Lung Epithelial Cells. Presented at the 6th Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, 2010.

Wise, S.S., Holmes, A.L., Xie, H., Martin, S., Pelsue, S.C., Thompson, W.D. and Wise Sr., J.P. Repeated Particulate Chromate Exposure Induces Chromosome Instability and a Subsequent DNA Double Strand Break Repair Deficient Phenotype and Neoplastic Transformation. Presented at the 6th Conference on Molecular Mechanism of Metal Toxicity and Carcinogenesis, Lexington, KY, 2010.

Li Chen, T., LaCerte, C., Shaffiey, F., Wise, S.S., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Hexavalent Chromium is More Clastogenic to Human Skin Fibroblasts than to Sperm Whale Skin Fibroblasts. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Savery, L.C., O’Brien, T.J., Holmes, A.L., Wise, Sr., J.P. and Patierno, S.R. Nucleotide Excision Repair Contributes to Hexavalent Chromium-Induced Double Strand Breaks and Chromosomal Damage. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference USM Research, Scholarship, and Creativity Symposium, 2010.

Doering, A., Wise, S.S, LaCerte, C., Chen, T.L, Martino, J., Martin, P., McGovern, D., Sample, A., Bickford, M, Goodwin, T.J., O’Hara, T. and Wise, Sr., J.P. Bowhead (Balaena mysticetus) Lung Cells are Resistant to Chromium-Induced Damage. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference USM Research, Scholarship, and Creativity Symposium, 2010.

Doucette, C.R., Holmes, A.L. and Wise, Sr., J.P. Mitotic Arrest Deficient (MAD) Protein Localization during Chromate-Induced Spindle Assembly Checkpoint Bypass. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference USM Research, Scholarship, and Creativity Symposium, 2010.

Karri, N.D., Holmes, A.L. and Wise, Sr., J.P. Role of Cdc20 and BubR1 Spindle Assembly Checkpoint Proteins in Chromate-Induced Spindle Assembly Checkpoint Bypass. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference USM Research, Scholarship, and Creativity Symposium, 2010.

LaCerte, C., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. During Which Division Does Chronic Exposure to Hexavalent Chromium Induce Chromosome Instability in Human Lung Cells? Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference USM Research, Scholarship, and Creativity Symposium, 2010.

Martino, J., Wise, S.S., Holmes, A.L., Xie, H. and Wise, Sr., J.P. Bowhead Whale Lung Cells Are Resistant to Cr-induced Genotoxicity Potential Mechanisms. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference USM Research, Scholarship, and Creativity Symposium, 2010.

Qin, Q., Holmes, A.L., Xie, H., Wise, S.S. and Wise, Sr., J.P. Chronic Exposure to Zinc Chromate Induces DNA Double Strand Breaks in Human Lung Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference USM Research, Scholarship, and Creativity Symposium, 2010.

Holmes, A.L., Wise, S.S., Pelsue, S., Lingle, W., Salisbury, J., Gallagher, J. and Wise, Sr., J.P. Prolonged Exposure to Zinc Chromate Induces Numerical Chromosome Instability via Centrosome Amplification in Human Lung Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference USM Research, Scholarship, and Creativity Symposium, 2010.

Wise, C.F., Wise, S.S., Li Chen, T., Mate, B.R., Kraus, S., Thompson, W.D. and Wise, Sr., J.P. A Tale of Two Whales: Toxic Effects of Hexavalent Chromium in Right Whale (Eubalaena glacialis) and Blue Whale (Balaenoptera musculus). Cells Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Davenport, J.A., Li Chen, T., Wise, S.S., Payne, R., Kerr, I. and Wise, Sr., J.P. Trivalent Chromium is Clastogenic to Sperm Whale Skin Fibroblasts. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Wise, Jr., J.P., Wise, S.S., Wise, J., McKay, J., Browne, M., Joyce, K., Braun, M., Wise, C.F., Duffy, R., Estell, E., Brown, J., Gianios, Jr., C., Mason, M., Shehata, T., Hammond, D. and Wise, Sr., J.P. Altered Gravity Exacerbates Chromate-Induced Genotoxicity Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Kreps, D., Wise, C.F., Wise, S.S. and Wise, Sr., J.P. Using Blueberry Extract to Prevent Arsenic Toxicity. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Braun, M., Leighton, R., Xie, H., Bickford, M., Lake, G., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Comparative Cytotoxicity and Genotoxicity of Mars, Earth and Moon Dusts in Human Skin Epithelial Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Wise, J., Duffy, R., Xie, H., LaCerte, C., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Comparative Toxicity of Lunar, Martian and Earth Dusts in Human Skin Fibroblast Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Joyce, K., LaCerte, C. and Wise, Sr., J.P. Depleted Uranium Induces Chromosome Hypercondensation in Human Bronchial Epithelial Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Lake, G., Xie, H., LaCerte, C., Martino, J., Leighton, R., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Toxicity of Lunar Dust on Human Brain Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

McKay, J. and Wise, Sr., J.P. Effects of Hypergravity on Chromate-Induced Toxicity in Bowhead Whale Lung Cells and Medaka Fish Fin Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Duffy, R., Wise, J., Xie, H., LaCerte, C., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Comparative Toxicity of Short-Term and Chronic Exposure to Lunar Dust and Its Component Particles in Human Skin Fibroblast Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Shively, B., Wise, Jr., J.P., Richardson, B., Krieg, E., Bickford, M. and Wise, Sr., J.P. Mars Dust is Genotoxic to Human Lung Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Wheeler, C., Wise, Jr., J.P. and Wise, Sr., J.P. Effects of Simulated Microgravity on Chromate Toxicity in Human Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

Wise, S.S., Holmes, A.L, Xie, H., Pelsue, S., Thompson, W.D. and Wise, Sr., J.P. Repeated Particulate Chromate Exposure Induces Chromosome Instability and a DNA Double Strand Break Repair-Deficient Phenotype in Human Lung Cells. Proceedings of the University of Southern Maine’s 7th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2010.

2000-2009

Wise, Sr., J.P. “Whales as Sentinels for Human Health: A Global Assessment of Chromium Pollution”, Annual Meeting of the Society of Toxicology, Baltimore, Maryland, 2009.

Xie, H., LaCerte, C. and Wise, Sr., J.P. A Potential Mechanism for Depleted Uranium-induced Carcinogenesis in Human Lung Epithelial Cells. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 104, 2009.

Wise, S.S., Holmes, A.L., Xie, H., Pelsue, S., Thompson, W.D. and Wise, Sr., J.P. Repetitive treatment of particulate chromate induces chromosome instability and a repair-deficient phenotype in human lung cells. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 103, 2009.

Wise, Sr., J.P, Holmes, A.L., Young, J.L., Savery, L.C., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Xie, H.Hexavalent Chromium Induces Chromosome Instability by Disrupting Mitosis and Inducing Centrosome Amplification in Human Lung Cells. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 103, 2009.

Wise, Sr., J.P., Kraus, S., Payne, R., Wise, S.S., Kerr, I., LaCerte, C., Wise, J., Gianios, Jr., C., Shaffiey, F., Grau, M., Li Chen, T., Perkins, C., Thompson, W.D., Zheng, T., Zhang, Y., Zhu, C. and O’Hara, T. Whales as Sentinels for Human Health: A Global Assessment of Chromium Pollution. Toxicological Sciences, 108: 1221, 2009.

LaCerte, C., Xie, H. and Wise, Sr., J.P. Depleted Uranium Induces Transformation in Human Bronchial Epithelial Cells. Toxicological Sciences, 108: 731, 2009.

Li Chen, T., Wise, S.S., Shaffiey F., Xie H., Holmes A.L., Kraus S.D. and Wise, Sr., J.P. Hexavalent Chromium Is More Clastogenic to Northern Right Whale Cells than Human Cells. Toxicological Sciences, 108: 1783, 2009.

Holmes, A.L., Buehler, D., Young, J., Wise, S.S., Jeevarajan, A., Wallace, W., Hammond, D. and Wise, Sr., J.P. Arsenic Synergistically Increases Zinc Chromate-Induced Aneuploidy and Spindle Assembly Checkpoint Bypass in Human Lung Cells. Toxicological Sciences, 108: 1773, 2009.

Wise, Jr. J.P., Wise, S.S., Wise, J., McKay, J., Courtemanche, A., Freedman, B., Browne, M., Gianios, Jr. C., Mason, M., Shehata, T., Hammond, D. and Wise, Sr., J.P. Altered Gravity Exacerbates Chromate-Induced Genotoxicity. Toxicological Sciences, 108: 1793, 2009.

Wise S.S., Mason M.D., Shaffiey F., Li Chen, T., Goodale, B., LaCerte, C., Craig, G., Walter, R., Payne, R., Kerr, I., Kraus, S. and Wise, Sr., J.P. Comparative Toxicity of Silver Nanoparticles in Human, Marine Mammal and Fish Cells. Toxicological Sciences, 108:1223, 2009.

Wise, J.T., LaCerte, C., Xie, H., Huang, J., McKay, J., Bickford, M., Okeny, M., Bousfield, D., Mason, M. and Wise, Sr., J.P. Are Cellulose Nanoparticles Toxic to Humans and Fish? Toxicological Sciences, 108: 876, 2009.

Young, J.L., Wise, Jr. J.P., Wise, J., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Lunar Dust and its Components are Cytotoxic to Human Lung Cells. Toxicological Sciences, 108: 1778, 2009.

Martino, J., Wise, Jr. J.P., Wise, J., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Aluminum Is More Cytotoxic than Lunar Dust in Human Skin and Lung Fibroblasts. Toxicological Sciences, 108: 1787, 2009.

Xie, H., LaCerte, C. and Wise, Sr., J.P. Mechanism of Carcinogenicity of Depleted Uranium in Human Lung Epithelial Cells. Toxicological Sciences, 108: 734, 2009.

Qin, Q., Xie, H., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Particulate Chromate Induced DNA Double Strand Breaks Are Associated with XPF Gene Activity in Human Lung Cells. Toxicological Sciences, 108: 735, 2009.

Wise, S.S., Li Chen, T., LaCerte, C., Martino, J., Doering, A., Martin, P., McGovern, D., Sample, A., Bickford, M., Goodwin, T.J., O’Hara, T. and Wise, Sr., J.P. Hexavalent Chromium Is More Clastogenic to Human Cells than Bowhead Whale (Balaena mysticetus) Cells. Toxicological Sciences, 108: 1785, 2009.

Duffy, R., Wise, J., Xie, H., LaCerte, C., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Cytotoxicity of Lunar Dust to Human Skin Fibroblast Cells. Toxicological Sciences, 108: 2305, 2009.

Wise, Sr., J.P. and De Guise, S. Aquatic Species as Sentinels for Human Health: Comparative Toxicology of Metals, Nanoparticles and PCBs. Toxicological Sciences, 108: 1220, 2009.

Duffy, R., Wise, J., LaCerte, C., Xie, H., Huang, J., Mckay, J., Bickford, M., Okeny, M., Bousfield, D., Mason, M. and Wise, Sr., J.P. Are Cellulose Nanoparticles Toxic to Humans and Fish? Proceedings of the 1st Annual Northeast Undergraduate Research Development Symposium, 2009.

McKay, J., Wise, Jr., J.P. and Wise, Sr., J.P. Effects of Hypergravity on Chromate-Induced Toxicity in Bowhead Whale Lung Cells. Proceedings of the 1st Annual Northeast Undergraduate Research Development Symposium, 2009.

Wise, J., Wise S.S. and Wise, Sr., J.P. Development of Amphibian Cell Lines for Toxicological Studies. Proceedings of the 1st Annual Northeast Undergraduate Research Development Symposium, 2009.

Wise, Jr. J.P., Wise, S.S., Wise, J., Wise, C.F., McKay, J., Braun, M., Courtemanche, A., Freedman, B., Browne, M., Hamilton, I., Brown, J., Gianios, Jr. C., Mason, M. and Wise, Sr., J.P. Dirigo, Maine’s First Student Team Aboard the Weightless Wonder: Effects of Altered Gravity on Cellular Function. Proceedings of the 1st Annual Northeast Undergraduate Research Development Symposium, 2009.

Martino, J., Wise, Jr., J.P., Wise, J., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Aluminum Is More Cytotoxic than Lunar Dust in Human Skin and Lung Fibroblasts. Proceedings of the 36th Maine Biological and Medical Sciences Symposium, 2009.

LaCerte, C., Xie, H. and Wise, Sr., J.P. Depleted Uranium Induces Transformation in Human Lung Epithelial Cells. Proceedings of the 36th Maine Biological and Medical Sciences Symposium, 2009.

Wise, Jr. J.P., Wise, S.S., Wise, J., McKay, J., Courtemanche, A., Freedman, B., Browne, M., Gianios, Jr. C., Mason, M., Shehata, T., Hammond, D. and Wise, Sr., J.P. Altered Gravity Exacerbates Chromate-Induced Genotoxicity. Proceedings of the 36th Maine Biological and Medical Sciences Symposium, 2009.

Young, J.L., Holmes, A.L., Qin, Q., Xie, H. and Wise, Sr., J.P. Zinc Chromate Induced Spindle Assembly Checkpoint Bypass and Chromosome Instability in Human Lung Cells. Proceedings of the 36th Annual Biological and Medical Science Symposium, 2009.

McKay, J., Wise, Jr., J.P. and Wise, Sr., J.P. Effects of Hypergravity on Chromate-Induced Toxicity in Bowhead Whale Lung Cells. Proceedings of the 36th Annual Biological and Medical Science Symposium, 2009.

Holmes, A.L., Buehler, D., Young, J., Wise, S.S., Jeevarajan, A., Wallace, W., Hammond, D. and Wise, Sr., J.P. Arsenic Synergistically Increases Zinc Chromate-Induced Aneuploidy and Spindle Assembly Checkpoint Bypass in Human Lung Cells. Proceedings of the 36th Annual Biological and Medical Science Symposium, 2009.

Chun, G., Wise, S.S., Wise Sr., J.P. Holmes, A.L., Patierno, S.R. and Ceryak, S.M. Protein tyrosine phosphatase inhibition enhances survival and chromosomal stability after genotoxin exposure at the expense of increased mutagenesis. Proceedings of the American Association for Cancer Research, 50: 464, 2009.

Atkinson, J., LaCerte, C., Wise, S.S., Gianios, Jr., C., Wise, J., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Arsenic Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 20, 2009.

Knowlton, C., LaCerte, C., Wise, S.S., Gianios, Jr., C., Wise, J., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Barium Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 130, 2009.

Marshall, K., LaCerte, C., Wise, S.S., Gianios, Jr., C., Wise, J., Payne, R. Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Cadmium Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 153, 2009.

Hayes, M., Wise, S.S., LaCerte, C., Gianios, Jr., C. Wise, J., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Copper Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 109, 2009.

Wise, J., LaCerte, C., Wise, S.S., Gianios, Jr., C., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Lead Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 278, 2009.

Kerr, I., LaCerte, C. Wise, S.S., Gianios, Jr., C., Wise, J., Evers, D., Payne, R., Thompson, W.D. and Wise, Sr., J.P. Mercury Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 128, 2009.

LaCerte, C., Wise, S.S., Shaffiey, F., Li Chen, T., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Comparison of Chromium Toxicity in Cells from Sperm Whales (Physeter macrocephalus) and Steller Sea Lions (Eumetopias jubatus). Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 136, 2009.

Wise, C.F., Wise, S.S., Li Chen, T., Mate, B.R., Kraus, S., Thompson, W.D. and Wise, Sr., J.P. A Tale of Two Whales: Toxic Effects of Hexavalent Chromium in Right Whale (Eubalaena glacialis) and Blue Whale (Balaenoptera musculus) Cells. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 278, 2009.

Gianios, Jr., C., LaCerte, C., Wise, S.S., Wise, J., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Marine Mammal Sightings in the Pacific Ocean Observed During the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 90, 2009.

Wise, Sr., J.P., Wise, S.S., LaCerte, C., Li Chen, T., Wise, J., Gianios, Jr., C., Payne, R., Kerr, I. and Thompson, W.D. Genotoxicity and Global Distribution of Chromium in Sperm Whale (Physeter macrocephalus) Skin Cells and Tissues. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 279, 2009.

Wise, Jr., J.P., LaCerte, C., Wise, S.S., Gianios, Jr., C., Wise, J., Payne, R., Kerr, I., Thompson, W.D., Mason, M.D. and Wise, Sr., J.P. Gold and Titanium Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 278, 2009.

Martino, J., Wise, S.S., Holmes, A.L., Thompson, W.D. and Wise, Sr., J.P. Hexavalent Chromium Is More Cytotoxic but Less Genotoxic to Bowhead Whale Lung Fibroblasts than Human Lung Fibroblasts. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 155, 2009.

Cain, S., LaCerte, C., Wise, S.S. Gianios, Jr., C., Wise, J., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Marine Mammal Sightings in the Indian Ocean Observed During the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 46, 2009.

McNamara, L., Wise, S.S., LaCerte, C., Gianios, Jr., Wise, J., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Nickel Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 162, 2009.

Wise, S.S., Mason, M.D., LaCerte, C., Li Chen, T., Craig, G., Walter, R., Payne, R., Kerr, I., Gianios, Jr., C., Wise, J., Thompson, W.D. and Wise, Sr., J.P. Silver nanoparticle toxicity in sperm whale (Physeter macrocephalus) cells and global distribution of silver levels in sperm whale skin tissue. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 278, 2009.

Li Chen, T., LaCerte, C., Shaffiey, F., Wise, S.S., Payne, R., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Sperm Whale Skin Fibroblasts Are More Resistant to Hexavalent Chromium Toxicity than Human Skin Fibroblasts. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 143, 2009.

Payne, R., LaCerte, C., Wise, S.S., Gianios, Jr., C, Wise, J., Kerr, I., Thompson, W.D. and Wise, Sr., J.P. Tin Levels in Sperm Whale (Physeter macrocephalus) Skin Biopsies Collected from around the Globe during the Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, 196, 2009.

Alexander, A.M., Payne, R., Kerr, I., Wise, Sr., J.P., Steel, D., Baker, C.S. Circum-equatorial survey of mtDNA diversity in the sperm whale (Physeter macrocephalus): Voyage of the Odyssey. Proceedings of the 18th Biennial Conference of the Biology of Marine Mammals, p.11, 2009.

Wise, Jr., J.P., Wise, S.S., Mason, M.D., Li Chen, T., LaCerte C., Craig, G., Walter, R., Payne, R., Kerr, I., Kraus, S. and Wise, Sr., J.P. Toxicity of Silver Nanoparticles in Human, Marine Mammal and Fish Cells. Proceedings of the 2nd USAF ASC/AFRL ESOH Nanomaterial Workshop, 2009.

Wise, Jr. J.P., Wise, S.S., Wise, J., McKay, J., Browne, M., Joyce, K., Braun, M., Wise, C.F., Duffy, R., Estell, E., Brown, J., Gianios, Jr. C., Mason, M., Shehata, T., Hammond, D. and Wise, Sr., J.P. Altered Gravity Exacerbates Chromate-Induced Genotoxicity. Gravitational and Space Biology, 23(1): 32, 2009.

Qin, Q., Xie, H., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Particulate Chromate Induced DNA Double Strand Breaks Are Associated with XPF Gene Activity in Human Lung Cells. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

McKay, J., Wise, Jr., J.P. and Wise, Sr., J.P. Effects of Hypergravity on Chromate-Induced Toxicity in Bowhead Whale Lung Cells. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Wise, J., Xie, H., LaCerte, C., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D. and Wise, Sr., J.P. Toxic Effects of Lunar Dust in Human Skin Fibroblast Cells. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Xie, H., Braun, M., McGovern, D., Li Chen, T., Bellino, J., Bessey, J. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Titanium Oxide in Human Skin Epithelial Cells. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Wise, S.S., Li Chen, T., LaCerte, C., Martino, J., Doering, A., Martin, P., McGovern, D., Sample, A., Bickford, M., Goodwin, T.J., O’Hara, T. and Wise, Sr., J.P. Hexavalent Chromium Is More Clastogenic to Human Cells than Bowhead Whale (Balaena mysticetus) Cells. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Martino, J., Li Chen, T., Duffy, R., Braun, M., Creisher, R., Rochester, B. and Wise, Sr., J.P. Do Whale Cells Have Better DNA Repair Than Human Cells? Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Li Chen, T., Wise, S.S., Shaffiey F., Xie H., Holmes A.L., Kraus S.D. and Wise, Sr., J.P. Hexavalent Chromium Is More Clastogenic to Human Cells than Northern Right Whale Cells. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

LaCerte, C., Xie, H. and Wise, Sr., J.P. Depleted Uranium is Cytotoxic, Clastogenic and Induces Transformation in Human Bronchial Epithelial Cells. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Martino, J., Wise, Jr., J.P., Wise, J., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Aluminum Is More Cytotoxic than Lunar Dust in Human Skin and Lung Fibroblasts. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Wise, Jr., J.P., Wise, S.S., Wise, J., McKay, J., Courtemanche, A., Freedman, B., Browne, M., Gianios, Jr., C., Mason, M., Shehata, T., Hammond, D. and Wise, Sr., J.P. Altered Gravity Exacerbates Chromate-Induced Genotoxicity. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Joyce, K., Mason, M.D., Craig, G. and Wise, Sr., J.P. Cytotoxicity of Depleted Uranium and Silver Nanoparticles in DNA Repair Deficient Cell Lines. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Young, J.L., Wise, Jr., J.P., Wise, J., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Lunar Dust and its Components are Cytotoxic to Human Lung Cells. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Braun, M., Wise, J., Duffy, R., LaCerte, C., Hong, X., Huang, J., Mckay, J., Bickford, M., Bousfield, D., Mason, M. and Wise, Sr., J.P. Are Cellulose Nanoparticles Toxic to Human Lung Fibroblast Cells? Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Wise, J., Wise, S.S., Wise, Sr., J.P., Gilliam, S. and Berquist, I. Development of Amphibian Cell Lines for Toxicological Studies. Proceedings of University of Southern Maine’s 6th Annual Thinking Matters: USM Research, Scholarship and Creativity Symposium, 2009.

Holmes, A.L., Buehler, D., Young, J., Wise, S.S., Jeevarajan, A., Wallace, W., Hammond, D. and Wise, Sr., J.P. Arsenic Synergistically Increases Zinc Chromate-Induced Aneuploidy and Spindle Assembly Checkpoint Bypass in Human Lung Cells. Proceedings of the University of Southern Maine’s 6th Annual Thinking Matters Conference: USM Research, Scholarship, and Creativity Symposium, 2009.

Wise, Sr., J.P. “Mechanisms of Hexavalent Chromium Induced Chromosome Instability”, Department of Chemistry, University of Alabama, 2008.

Wise, Sr., J.P. “STEM Education in the Wise Laboratory”, First Annual Conference on Science, Technology, Engineering and Math (STEM) Education in Maine, Augusta, Maine, 2008.

Goodale, B.C., Walter, R., Pelsue, S.R., Thompson, W.D., Wise, S.S., Winn, R.N., Mitani, H., Wise, Sr., J.P. Medaka Cell Lines as Tools for Mechanistic Toxicity Studies. Proceedings of the Aquatic Models of Human Disease Conference, 63-64, 2008.

Holmes, A.L., Qin, Q., Young, J.L., Joyce, K., Xie, H., Cavas, T. and Wise, Sr., J.P. Chronic Exposure to Zinc Chromate Induces Chromosome Instability in Human Lung Cells. Toxicological Sciences, 102: 2093, 2008.

Xie, H., Holmes, A.L., Joyce, K. Pelsue, S.R., Cavas, T., Young, J.L., Qin, Q. and Wise, Sr., J.P. Zinc Chromate Induces Chromosome Instability and DNA Double Strand Breaks in Human Lung Cells. Proceedings of the American Association for Cancer Research, 49: 4731, 2008.

Holmes, A.L., Wise, S.S., Qin, Q., Young, J.L., Keierleber, J., Xie, H., Cavas, T., Schuler, J.H.C., Katsifis, S.P., Ketterer, M.E., Hartsock, W.J., Thompson, W.D. and Wise, Sr., J.P. Comparative Genotoxicity and Cytotoxicity of Four Hexavalent Chromium Compounds in Human Bronchial Cells. Proceedings of the American Association for Cancer Research, 49: 4730, 2008.

Young, J.L., Holmes, A.L., Qin, Q., Xie, H. and Wise, Sr., J.P. Zinc Chromate Induces Spindle Assembly Checkpoint Bypass and Chromosome Instability in Human Lung Cells. Proceedings of the American Association for Cancer Research, 49: 4729, 2008.

Wise, S.S., Holmes, A.L., Xie, H., Pelsue, S.R., Thompson, W.D. and Wise, Sr., J.P. Repeated exposure to particulate chromate induces a DNA double strand break repair-deficient phenotype and chromosome instability in human lung cells. Proceedings of the American Association for Cancer Research, 49: 1873, 2008.

Xie, H., Holmes, A.L., Joyce, K., Pelsue, S.R., Cavas, T., Young, J.L., Qin Q. and Wise, Sr., J.P. Particulate Chromium Induces Chromosome Damage and DNA Double Strand Breaks in Human Lung Cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Keierleber, J., Xie, H. and Wise, Sr., J.P. Cytotoxic and Genotoxic Effects of Zinc Chromate on Human Lung Cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

LaCerte, C., Xie, H. and Wise, Sr., J.P. Depleted Uranium Induces Neoplastic Transformation in Human Lung Epithelial Cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Martino, J., Li Chen, T., Wise, S., LaCerte, C., Keierleber, J., Kraus, S. and Wise, Sr., J.P. Zinc Chromate Cytotoxicity on Human and Right Whale Cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Young, J.L., Holmes, A.L., Qin, Q., Xie, H. and Wise, Sr., J.P. Zinc Chromate Induces Spindle Assembly Checkpoint Bypass and Chromosome Instability in Human Lung Cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Qin Q., Wise, S.S, Michael D. Mason, D.M, Xie, H. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Gold Nanoparticles in Human Lung Cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Li Chen, T., Martino, J., Wise, S.S., Holmes, A., Shaffiey, F., Popa, O., Goertz, C.E.C., Kraus, S., Dunn, J.L., Gulland, F.M., Thompson, W.D., Zheng, T. and Wise, Sr., J.P. Chromium-Contaminated Environments Are a Health Concern for Humans and Wildlife. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Holmes, A.L., Wise, S.S., Qin, Q., Young, J.L., Keierleber, J., Xie, H., Cavas, T., Schuler, J.H.C., Katsifis, S.P., Ketterer, M.E., Hartsock, W.J., Thompson, W.D. and Wise, Sr., J.P. Comparative genotoxicity and cytotoxicity of four hexavalent chromium compounds in human bronchial cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Wise S.S., Holmes A.L., Xie H., Pelsue S., Thompson W.D. and Wise, Sr., J.P. Repeated exposure to particulate chromate induces a repair-deficient phenotype and chromosome instability in human lung cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Wise, J., LaCerte, C., Xie, H., Huang, J., Okeny, M. and Wise, Sr., J.P. Are Cellulose Nanoparticles Toxic to Humans? Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Goodale, B.C., Walter, R., Pelsue, S.R., Thompson, W.D., Wise, S.S., Winn, R.N., Mitani, H. and Wise, Sr., J.P. Medaka Cell Lines as Tools for Mechanistic Toxicity Studies. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Shaffiey, F., Wise, S.S., Goertz, C.E.C., LaCerte, C., Dunn, J.L., Gulland, F.M.D., Thompson, W.D., Zheng T. and Wise, Sr., J.P. Cytotoxicity and Clastogenicity of Hexavalent Chromium in Steller Sea Lion Lung Cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Wise, Jr., J.P., Xie, H., Wallace, W. Hammond, D., Jeevarajan, A. and Wise, Sr., J.P. Colonizing the Moon: A Study of the Toxic Effects of Lunar Dust on Human Lung Cells. Presented at Making the Connection III: Toxics and Tomorrow’s Children Conference, 2008.

Wise, Sr., J.P., Wise, S.S, Kraus, S., Shaffiey, F., Grau, M., Li Chen, T., Perkins, C., Thompson, W.D., Zheng, T., Zhang, Y., Romano, T. and O’Hara, T. Hexavalent Chromium May Threaten the Heath of the North Atlantic Right Whale (Eubalaena glacialis). Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 39: 2, 2008.

Wise, S.S., Payne, R., LaCerte, C., Wise, J., Gianios, Jr., C., Perkins, C., Zheng, T., Zhu, C., Kerr, I. and Wise, Sr., J.P. Chromium in Sperm Whales: A Global Assessment. Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 39: 3, 2008.

Wise, J., Wise, Jr. J.P., Xie, H., LaCerte, C., Yong, J., Mason, M., Jeevarajan, A., Wallace, W., Hammond, D. and Wise, Sr., J.P. Toxic Effects of Lunar Dust in Human Lung Fibroblast Cells. Presented at the Maine Space Grant Consortium Annual Meeting. 2008.

Martino, J., Li Chen, T., Wise, S.S., Shaffiey, F., Popa, O., Goertz, C.E.C., Kraus, S., Dunn, J.L., Gulland, F.M.D., Thompson, W.D., Zheng, T. and Wise, Sr., J.P. Cytotoxic and Genotoxic Effects of Chromium on Marine Mammal Lung Cells. Proceedings of the Annual Meeting of the North Atlantic Chapter of the Society for Environmental Toxicology and Chemistry, 2008.

Li Chen, T., Wise, S.S, Kraus, S., Shaffiey, F., Grau, M., Perkins, C., Thompson, W.D., Zheng, T., Zhang, Y., Romano, T. and O’Hara, T. and Wise, Sr., J.P. Hexavalent Chromium May Be a Risk Factor for the North Atlantic Right Whale (Eubalaena glacialis). Proceedings of the Annual Meeting of the North Atlantic Chapter of the Society for Environmental Toxicology and Chemistry, 2008.

Xie, H., LaCerte, C. and Wise, Sr., J.P. Carcinogenicity of Depleted Uranium in Human Lung Epithelial Cells. Proceedings of the Fifth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis. National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia, 2008.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Particulate Hexavalent Chromium Induces Centrosome Amplification Resulting in Chromosome Instability in Human Lung Cells. Proceedings of the Fifth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis. National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia, 2008.

Wise S.S., Mason M.D., Shaffiey F., Li Chen, T., Goodale, B., LaCerte, C., Craig, G., Walter, R., Payne, R., Kerr, I., Kraus, S. and Wise, Sr., J.P. Comparative Toxicity of Silver Nanoparticles in Human, Marine Mammal and Fish Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 27, 2008.

Holmes, A.L., Buehler, D., Young, J., Wise, S.S., Jeevarajan, A., Wallace, W., Hammond, D. and Wise, Sr., J.P. Arsenic Potentiates Particulate Chromate-Induced Chromosome Instability. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 14, 2008.

Martino, J., Wise, Jr. J.P., Wise, J., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Aluminum Is More Cytotoxic than Lunar Dust in Human Skin and Lung Fibroblasts. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 18, 2008.

Young, J.L., Wise, Jr. J.P., Wise, J., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Lunar Dust and its Components are Cytotoxic to Human Lung Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 30, 2008.

Qin, Q., Xie, H., Jeevarajan, A., Wallace, W., Hammond, D., Shehata, T. and Wise, Sr., J.P. Particulate Chromate Induced DNA Double Strand Breaks Are Associated with XPF Gene Activity in Human Lung Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 23, 2008.

Wise, J.T., LaCerte, C., Xie, H., Huang, J., McKay, J., Bickford, M., Okeny, M., Bousfield, D., Mason, M. and Wise, Sr., J.P. Are Cellulose Nanoparticles Toxic to Humans and Fish? Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 25, 2008.

Wise, Jr., J.P., Wise, S.S., Wise, J., McKay, J., Courtemanche, A., Freedman, B., Browne, M., Gianios, Jr. C., Mason, M., Shehata, T., Hammond, D. and Wise, Sr., J.P. Altered Gravity Exacerbates Chromate-Induced Genotoxicity. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 26, 2008.

Li Chen, T., Wise, S.S., Shaffiey, F., Xie, H., Holmes, A.L., Kraus, S.D. and Wise, Sr., J.P. Hexavalent Chromium Is More Clastogenic to Northern Right Whale Cells than Human Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 6, 2008.

LaCerte, C., Xie, H. and Wise, Sr., J.P. Depleted Uranium Induces Transformation in Human Bronchial Epithelial Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 17, 2008.

Xie, H., LaCerte, C. and Wise, Sr., J.P. Depleted Uranium Has Genotoxic and Epigenetic Effects in Human Lung Epithelial Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 28, 2008.

Qin, Q., Wise, S.S, Mason, M.D., Xie H. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Gold Nanoparticles in Human Lung Cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 41, 2008.

Young, J.L., Holmes, A.L., Qin, Q., Xie, H. and Wise, Sr., J.P. Zinc Chromate Induces Spindle Assembly Checkpoint Bypass and Chromosome Instability in Human Lung Cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 156, 2008.

Keierleber, J., Xie, H. and Wise, Sr., J.P. Cytotoxic and Genotoxic Effects of Zinc Chromate on Human Lung Cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 40, 2008.

LaCerte, C., Xie, H. and Wise, Sr., J.P. Depleted Uranium Induces Neoplastic Transformation in Human Lung Epithelial Cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 45, 2008.

Martino, J., Li Chen, T., Wise, S., LaCerte, C., Keierleber, J., Kraus, S. and Wise, Sr., J.P. Zinc Chromate Cytotoxicity on Human and Right Whale Cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 155, 2008.

Goodale, B.C., Walter, R., Pelsue, S.R., Thompson, W.D., Wise, S.S., Winn, R.N., Mitani, H. and Wise, Sr., J.P. Medaka Cell Lines as Tools for Mechanistic Toxicity Studies. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 106, 2008.

Shaffiey, F., Wise, S.S., Goertz C.E.C., LaCerte, C., Dunn, J.L., Gulland, F.M.D., Thompson W.D., Zheng T. and Wise, Sr., J.P. Cytotoxicity and Clastogenicity of Hexavalent Chromium in Steller Sea Lion Lung Cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 39, 2008.

Wise, Jr. J.P., Wise, S.S., Wise, J.T.F., Link, N., Courtemanche, A., Freedman, B., Browne, M., Gianios, Jr., C., Mason, M. and Wise, Sr., J.P. DIRIGO: Maine’s First Student Team in Microgravity. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 51, 2008.

Wise, Jr., J.P., Xie, H., Wallace, W., Hammond, D., Jeevarajan, A. and Wise, Sr., J.P. The Toxicity of Lunar Dust in Human Lung Epithelial Cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 151, 2008.

Wise, Jr., J.P., Wise, J.T.F., Ford, J. and Wise, Sr., J.P. Protocol Development: Cells in Microgravity. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 20, 2008.

Wise, J., LaCerte, C., Xie, H., Huang, J., Okeny, M. and Wise, Sr., J.P. Are Cellulose Nanoparticles Toxic to Humans? Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 8, 2008.

Wise S.S., Holmes A.L., Xie H., Pelsue S., Thompson W.D. and Wise, Sr., J.P. Repeated exposure to particulate chromate induces a repair-deficient phenotype and chromosome instability in human lung cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 132, 2008.

Holmes, A.L., Wise, S.S., Qin, Q., Young, J.L., Keierleber, J., Xie, H., Cavas, T., Schuler, J.H.C., Katsifis, S.P., Ketterer, M.E., Hartsock, W.J., Thompson, W.D. and Wise, Sr., J.P. Comparative genotoxicity and cytotoxicity of four hexavalent chromium compounds in human bronchial cells. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 34, 2008.

Li Chen, T., Martino, J., Wise, S.S., Holmes, A., Shaffiey, F., Popa, O., Goertz, C.E.C., Kraus, S., Dunn, J.L., Gulland, F.M., Thompson, W.D., Zheng, T. and Wise, Sr., J.P. Chromium-Contaminated Environments Are a Health Concern for Humans and Wildlife. Proceedings of University of Southern Maine’s 5th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 31, 2008.

Wise, Sr., J.P. “The Toxicology of Chromium in Great Whales: Is Chromium the Next Global Pollutant?”, Department of Biology, University of Southern Maine, Portland, Maine, 2007.

Bank, M. S., Crocker, J.B., Wachtl, J., Kleeman, P., Currens, C., Fellers, G., May, J., Hothem, R., Madej, M.A. and Wise, J. Mercury in giant stream salamanders from west coast national parks. Presented at the National Park Service Natural Resource Education Symposium, Marin Headlands Institute, Golden Gate National Recreation Area, Sausalito, California, 2007.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Centrosome Amplification is a Mechanism for Genomic Instability Induced by Environmental Carcinogens in Human Lung Cells. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 161, 2007.

Wise, S.S., Holmes, A.L., Xie, H., Thompson, W.D. and Wise, Sr., J.P. Chemical Carcinogens Target the Centromere to Induce Chromosome Instability in Human Lung Cells. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 344, 2007.

Xie, H., Wise, S.S. and Wise, Sr., J.P. MRE11 Protects Cells from DNA Double Strand Break-Induced Neoplastic Transformation. Proceedings of the Keystone Symposia on Genomic Instability and Repair, 346, 2007.

Savery, L.C., Xie, H., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Particulate Hexavalent Chromium Induces Chromosome Instability and Decreased Expression of Spindle Assembly Checkpoint Proteins. Toxicological Sciences, 96: 635, 2007.

Stackpole, M.M., Wise, S.S., Duzevik, E.G., Munroe R.C., Thompson, L.H., Thacker, J. and Wise, Sr., J.P. Rad51D, XRCC3 and Rad51C Play a Role in Repairing Chromate-Induced Chromosome Instability in Mammalian Cells by Homologous Recombination. Toxicological Sciences, 96: 1082, 2007.

Huang, S., Xie, H., Peng, C., Gupta, B.C. and Wise, Sr., J.P. Microarray Analysis of Particulate Chromate-Induced Gene Changes in Human Lung Cells. Toxicological Sciences, 96: 1083, 2007.

Xie, H., Wise, S.S. and Wise, Sr., J.P. Impaired Repair of Particulate Cr(VI)-induced DNA Double Strand Breaks Leading to Neoplastic Transformation. Toxicological Sciences, 96: 1084, 2007.

Wise, S.S., Shaffiey, F., LaCerte, C., Payne, R., Kerr, I.A.R., Kraus, S. and Wise, Sr., J.P. The Effects of Chromium on Human, Sperm Whale and North Atlantic Right Whale Cells. Proceedings of the 14^th International Pollution Responses in Marine Organisms (PRIMO) Symposium, 107, 2007.

Li Chen, T., Wise, S.S., Kraus, S., O’Hara, T., Kerr, I.A.R., Payne, R. and Wise, Sr., J.P. Genotoxicity of Mercury in the North Atlantic Right Whale (Eubalaena glacialis) and in the Sperm Whale (Physeter macrocephalus). Proceedings of the 14^th International Pollution Responses in Marine Organisms (PRIMO) Symposium, 105, 2007.

Wise, S.S., Mason, M.D., Shaffiey, F., Li Chen, T., Goodale, B., Craig, G., Walter, R., Payne, R., Kerr, I.A.R., Winn, R. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Silver Nanoparticles in Target Species. Proceedings of the 14^th International Pollution Responses in Marine Organisms (PRIMO) Symposium, 101, 2007.

Wise, S.S., LaCerte, C., Wise, Jr., J.P., Kerr, I.A.R., Payne, R., Evers, D. and Wise, Sr., J.P. The Effects of Chromium Exposure and Its Toxicity in the Sperm Whale. Proceedings of the 14^th International Pollution Responses in Marine Organisms (PRIMO) Symposium, 102, 2007.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Environmental Carcinogens Induce Chromosome Instability through Centrosome Amplification in Human Lung Cells. Proceedings of the 7^th International Chromosome Segregation and Aneuploidy Workshop, T36, 2007.

Savery, L.C., Holmes, A.L., Sandwick, S.J., Xie, H., Wise, S.S. and Wise, Sr., J.P. Lead Chromate Induced Chromosome Instability and Decreased Expression of Key Spindle Assembly Checkpoint Proteins. Proceedings of the 7^th International Chromosome Segregation and Aneuploidy Workshop, T33, 2007.

Wise, S.S., Mason M.D., Holmes, A.L., Savery, L., Li Chen, T., Goodale, B., Shaffiey, F., Wise, Jr., J.P., Craig, G., Walter, R., Payne, R., Kerr, I., Spaulding, M. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human and Marine Cell Lines. Environmental and Molecular Mutagenesis, 48(7): 606, 2007.

Wise, Sr., J.P., Wise, S.S., Kraus, S., Shaffiey, F., Grau, M., Li Chen, T., Perkins, C., Thompson, W.D., Zheng, T., Zhang, Y., Romano, T. and O’Hara, T. The Cytotoxic and Genotoxic of Hexavalent Chromium in North Atlantic Right Whale (Eubalaena glacialis) Cells. Proceedings of the Annual Meeting of the North Atlantic Right Whale Consortium, 2007.

Wise, S.S., Wise, Jr., J.P., Xie, H., Mason M.D., Craig, G., Payne, R., Kerr, I.A.R. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Silver Nanoparticles in Sperm Whale Cells. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 295, 2007.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Centrosome Amplification is a Mechanism for Genomic Instability Induced by Environmental Carcinogens in Human Lung Cells. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 9, 2007.

Li Chen, T., Wise, S.S., Krauss, S. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Mercury and TBT in the North Atlantic Right Whale. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 21 , 2007.

Shaffiey, F., Wise, S.S., Kraus S., O’Hara T. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Cr(VI) in Lung and Testes Cells From The Northern Right Whale (Eubalaena glacialis) Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 19, 2007.

LaCerte, C., Kerr, I., Payne, R., Evers, D., Wise, S.S. and Wise, Sr., J.P. Chromium Exposure and its Toxicology in the Sperm Whale. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 11, 2007.

Savery, L.C., Xie, H., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Lead Chromate Induces Chromosome Instability and Decreased Expression of Spindle Assembly Checkpoint Proteins. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 68, 2007.

Goodale, B., Je, Z., Walter R., Winn, R., Wise, S.S. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Hexavalent Chromium in Medaka Cells and Interactions with Hypoxia. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 20, 2007.

Qin Qin, Wise S.S, Mason M., Hong Xie, Oberdorster G. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Copper Nanoparticles in Human Lung Cells. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 18, 2007

Huang, S., Xie, H., Peng, C., Gupta, B. and Wise, Sr., J.P. Particulate Chromate-Induced Gene Changes in Microarrays. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 84, 2007.

Bresler, A., Grebliunaite, R., Karaczyn, A. and Wise, Sr., J.P. In Vitro Toxicity of Depleted Uranium in Human Bronchial Epithelial Cells. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 60, 2007.

Uygur, B., Wise, S.S., Mason, M., Ng, A.K. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Silver Nanoparticles. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 17, 2007.

Stackpole, M. Wise, S.S., Duzevik, E., Munroe, R. and Wise, Sr., J.P. Rad51, XRCC3 and Rad51C Protect Cells from Particulate Chromate-induced Chromosome Instability in Mammalian Cells. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 95, 2007.

Gurney, A., Holmes, A., Savery, L., Wise, S.S. and Wise, Sr., J.P. Influence of Vitamin B2 and Vitamin E on DNA damage, Chromosome Instability and Cytotoxicity Induced by Lead Chromate in Human Lung Fibroblast Cells (WTHBF-6). Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 62, 2007.

Knight, T., Venkata, C. Wise, S.S., Mason, M., Thompson, D., Wise, Sr., J.P. and Ng, A.K. Cytotoxic and Inflammatory Effects of 15 nm Gold Nanoparticles. Proceedings of University of Southern Maine’s 4^th Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 16, 2007.

Wise, Sr., J.P. “Metal Toxicity and Carcinogenesis”, Fourth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia, 2006.

Wise, Sr., J.P. “Sperm Whales: Are They Exposed to Dangerous Levels of Metals and Are They Sentinels for Human Health? A Case Study of the Toxic Effects of Chromium”, Voyage of the Odyssey Science Symposium II, Pacific Life Foundation, Newport Beach, California, 2006.

Wise, Sr., J.P. “Sperm Whales: Are They Exposed to Dangerous Levels of Metals and Are They Sentinels for Human Health? A Case Study of the Toxic Effects of Chromium”, Consultative Group on Biological Diversity’s Annual Marine Working Group, San Pedro, Ambergris Caye, Belize, 2006.

Wise, S.S., Pfefferle, L., Goodale, B., Bresler, A., Ng, A. and Wise, Sr., J.P. The Genotoxicity of Carbon Single-Walled Nanotubes in Human Bronchial Cells. Proceedings of the international symposium: Nanotoxicology Biomedical Aspects, 2006.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Chronic Exposure to Lead Chromate Causes Centrosome Amplification and Aneuploidy in Human Lung Cells. Toxicological Sciences, 90: 519, 2006.

Xie, H, Dako, S., Wise, S.S., Katsifis, S. and Wise, Sr., J.P. ATM and MRE11 Are Involved in the Repair of Particulate Chromium (VI)-Induced DNA Double Strand Breaks. Toxicological Sciences, 90: 544, 2006.

Savery, L.C., Wise, S.S. and Wise, Sr., J.P. Particulate Chromium Induced DNA-DNA Crosslinks Lead to Chromosome Damage. Toxicological Sciences, 90: 545, 2006.

Wise, Sr., J.P. Sperm Whales: Are They Exposed to Dangerous Levels of Metals and Are They Sentinels for Human Health? A Case Study of the Toxic Effects of Chromium. Proceedings of the Consultative Group on Biological Diversity’s Annual Marine Working Group, 2006.

Wise, S.S., Kirstein, D., Romano, T. and Wise, Sr., J.P. The National Marine Cell Line Library. Proceedings of the annual meeting of the Northeast Regional Stranding Network, 2006.

Wise, S.S., Holmes, A., Xie, H., Mason, M.D., Chada, V.G.R., Goodale, B., Shaffiey, F., LaCerte, C., Qin, Q., Ng., A.K. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Gold Nanospheres in Human Lung Cells. Presented at the workshop: Overcoming Obstacles to Effective Research Design in Nanotoxicology, 2006.

Wise, S.S., Pfefferle, L., Goodale, B., Bresler, A., Ng, A. and Wise, Sr., J.P. The Genotoxicity of Carbon Single-Walled Nanotubes in Human Bronchial Cells. Presented at the workshop: Overcoming Obstacles to Effective Research Design in Nanotoxicology, 2006.

Knight, T., Wise, S.S., Wise, Sr., J.P. and Ng, A.K. Immunological and Toxic Effects of Gold Nanoparticles. Presented at the workshop: Overcoming Obstacles to Effective Research Design in Nanotoxicology, 2006.

Duzevik, E.G., Wise, S.S., Munroe, R.C. and Wise, Sr., J.P. XRCC1 Is Involved in Repair of Lead Chromate-Induced Chromosome Damage. Proceedings of the American Association for Cancer Research, 47: 1072, 2006.

Karaczyn, A.A., Xie, H. and Wise, Sr., J.P. Depleted Uranium-Induced Malignant Transformation in Human Lung Epithelial Cells. Proceedings of the American Association for Cancer Research, 47: 5215, 2006.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Lead Chromate-Induced Chromosome Instability is Caused by Centrosome Amplification in Human Lung Cells. Proceedings of the American Association for Cancer Research, 47: 1088, 2006.

Xie, H, Wise, S.S., Dako, S., Katsifis, S. and Wise, Sr., J.P. Functional Role of MRE11 in the Repair of Particulate Chromium (VI)-Induced DNA Double Strand Breaks. Proceedings of the American Association for Cancer Research, 47: 1086, 2006.

Savery, L.C., Wise, S.S. and Wise, Sr., J.P. Lead Chromate Induces DNA-DNA Crosslinks Leading to Chromosome Damage. Proceedings of the American Association for Cancer Research, 47: 1084, 2006.

Wise, S.S., Stackpole, M.M., Camrye, E., Duzevik, E.G. and Wise, Sr., J.P. Particulate Chromate-Induced Chromosome Instability Is Attenuated by Non-Homologous End Joining and Homologous Recombination Repair. Proceedings of the American Association for Cancer Research, 47: 1087, 2006.

Wise, S.S., Kelly, R.S., Throckmorton, H., Kraus, S., O’Hara, T., Romano, T. and Wise, Sr., J.P. The Effect of Environmental Contaminants: Chromium, Mercury and Tributyltin, on Northern Atlantic Right Whale Cells. Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 37: 110, 2006.

Goodale, B.C., Wise, S.S., Walter, R.B., Ju, Z. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Hexavalent Chromium and Hypoxia in Medaka Cells. Proceedings of the North Atlantic Chapter of the Society or Environmental Toxicology and Chemistry, 2006.

Shaffiey, F., Wise, S.S., Kraus, S., O’Hara, T. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Cr(VI) in Lung and Testes Cells from the Northern Right Whale (Eubalaena glacialis). Proceedings of the North Atlantic Chapter of the Society or Environmental Toxicology and Chemistry, 2006.

Throckmorton, H., Wise, S.S., Kelly, R., Kraus, S., O’Hara, T., Romano, T. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Mercury in Bowhead Whale (Balaena mysticetus) and Human Lung Cells. Proceedings of the North Atlantic Chapter of the Society of Environmental Toxicology and Chemistry, 2006.

LaCerte, C., Wise, S.S., Wise, Jr., J.P., Kerr, I.A.R., Payne, R., Evers, D. and Wise, Sr., J.P. Chromium Exposure and Its Toxicity in the Sperm Whale. Proceedings of the North Atlantic Chapter of the Society of Environmental Toxicology and Chemistry, 2006.

Bank, M.S., Crocker, J.B., Wachtl, J.L., Kleeman, P., Currens, C., Fellers, G., May, J., Hothem, R., Wise, J.P. and Madej, M.A. Mercury Bioaccumulation in Pacific Giant Salamander Larvae from Lotic Ecosystems in the Pacific Northwestern United States. Presented at the Conference on Mercury as a Global Pollutant (Mercury 2006), Madison, Wisconsin, 2006.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Lead Chromate Induces Chromosome Instability via Centrosome Amplification and Spindle Assembly Checkpoint Bypass in Human Lung Cells. Proceedings of the Fourth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis. National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia, 2006.

Xie, H., Wise, S.S., Dako, S., Katsifis, S. and Wise, Sr., J.P. Impaired Repair of Lead Chromate-Induced DNA Double Stand Break Leads To Neoplastic Transformation. Fourth Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis. National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia, 2006.

Savery, L.C., Grlickova-Duzevik, E., Wise, S.S., Thompson, W.D., Hinz, J.M., Thompson, L.H. and Wise, Sr., J.P. Fancg Gene Protects Cells from Particulate Chromate-Induced Chromosome Instability. Proceedings of the EPA Graduate Fellowship Conference, 2006.

Karaczyn, A.A., Xie, H, Cheng, R.Y.S. and Wise, Sr., J.P. In Vitro Toxicity and Neoplastic Transformation of Depleted Uranium: Effects on Human Bronchial Epithelial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Lead Chromate-Induced Chromosome Instability and Centrosome Amplification Is Not Mediated by Lead. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Uygur, B., Wise, S.S., Mason, M.D., Ng, A.K. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Silver Nanoparticles. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Goodale, B.C., Wise, S.S., Walter, R.B., Ju, Z., Winn, R.N. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Hexavalent Chromium in Medaka Cells and Interactions with Hypoxia. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Shaffiey, F., Wise, S.S., Kraus, S., O’Hara, T. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Cr(VI) in Lung and Testes Cells from the Northern Right Whale (Eubalaena glacialis). Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Xie, H., Wise, S.S. and Wise, Sr., J.P. Functional Role of MRE11 in the Repair of Particulate Cr(VI)-induced DNA Double Strand Breaks. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Savery, L.C., Xie, H., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Particulate Hexavalent Chromium Causes Chromosome Instability through Decreased Expression of Spindle Assembly Checkpoint Proteins. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Stackpole, M.M., Wise, S.S., Duzevik, E.G., Munroe R.C., Thompson, L.H., Thacker, J. and Wise, Sr., J.P. Homologous Recombination Repair Protects Against Chromate-induced Chromosome Instability in Chinese Hamster Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Qin, Q., Wise, S.S., Oberdorster, G., Mason, M.D., Xie, H. and Wise, Sr., J.P. The Cytotoxicity of Copper Nanoparticles in Human Lung Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Wise, S.S., Mason, M.D., Chada, V.G.R, LaCerte, C, Ng, A.K. and Wise, Sr., J.P. The Cytotoxicity of Gold Nanospheres in Human Lung Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Huang, S., Xie, H., Peng, C., Gupta, B.C. and Wise, Sr., J.P. Particulate Chromate-Induced Gene Changes in Microarrays. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Li Chen, T., Wise, S.S., Kraus, S., O’Hara, T. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Mercury and TBT in the Northern Atlantic Right Whale. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2006.

Goodale, B.C., Wise, S.S., Walter, R.B., Ju, Z. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Hexavalent Chromium and Hypoxia in Medaka Cells. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 114, 2006.

Shaffiey, F., Wise, S.S., Kraus, S., O’Hara, T. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Cr(VI) in Lung and Testes Cells from the Northern Right Whale (Eubalaena glacialis). Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 316, 2006.

Wise, S.S., LaCerte, C., Wise, Jr., J.P., Kerr, I.A.R., Payne, R., Evers, D. and Wise, Sr., J.P. Chromium Exposure and Its Toxicity in the Sperm Whale. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 316, 2006.

Li Chen, T., Wise, S.S., Kraus, S., O’Hara, T. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Mercury and TBT in the Northern Atlantic Right Whale. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 316, 2006.

Wise, S.S., Goertz, C.E.C, Morin, A.T., Dunn, J.L., Gulland, F.M.D., Bozza, M., Atkinson, S., Thompson, W.D. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Chromium in Steller Sea Lion Lung, Skin and Testes Cells. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 316, 2006.

Bank, M.S., Crocker, J.B. Wachtl, J. Kleeman, P., Currens, C., Fellers, G., May, J., Hothem, R., Wise, J. and Madej, M.A. Spatial Variation in Mercury Bioaccumulation, Energy Flow and Trophic Complexity in Giant Salamanders from the Pacific Northwestern United States. Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 345, 2006.

Wise, S.S., Throckmorton, H., Li Chen, T., Kraus, S., O’Hara, T. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Chromium and Mercury in Bowhead and North Atlantic Right Whale Cells. Proceedings of the Annual Meeting of the North Atlantic Right Whale Consortium, 2006.

Bresler, A., Wise, S.S., Walter, R.B., Ju, Z. and Wise, Sr., J.P. Characterization and Lifespan Extension of Elephant Seal (Mirounga anustirostris). Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 16, 2006.

West, C., Holmes, A., Wise, Sr., J.P. and Gordon, N. Chromium Distribution and Speciation of Urban Soils in the West End of Portland, Maine. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 17, 2006.

Goodale, B.C., Wise, S.S., Walter, R.B., Ju, Z. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Hexavalent Chromium and Hypoxia in Medaka Cells. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 29, 2006.

Shaffiey, F., Wise, S.S., Kraus, S., O’Hara, T. and Wise, Sr., J.P. The Cytotoxicity and Genotoxicity of Cr(VI) in Lung and Testes Cells from the Northern Right Whale (Eubalaena Glacialis). Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 90, 2006.

Throckmorton, H., Wise, S.S., Kelly, R., Kraus, S., O’Hara, T., Romano, T. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Mercury in Bowhead Whale (Balaena Mysticetus) and Human Lung Cells. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 30, 2006.

Knight, T., Mason, M., Wise, S.S., Wise, Sr., J.P. and Ng, A.K. Cytotoxic and Proinflammatory Effects of Gold Nanoparticles on Immune Cells and Lung Cells. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 27, 2006.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Lead Chromate-Induced Chromosome Instability Is Caused by Centrosome Amplification in Human Lung Cells. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 65, 2006.

Slaymaker, I.M., Savery, L.C. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Chronic Exposures to Zinc Chromate, Barium Chromate and Strontium Chromate. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 28, 2006.

Bui, K.S., Holmes, A.L. and Wise, Sr., J.P. Chronic Exposure to Lead Chromate Causes an Increase in Aberrant Mitosis in Human Lung Cells. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 18, 2006.

Sandwick, S.J., Karaczyn, A.A. and Wise, Sr., J.P. In Vitro Toxicity and Neoplastic Transformation of Depleted Uranium: Effects on Human Bronchial Epithelial Cells. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 58, 2006.

Huang, S., Xie, H., Peng, C., Gupta, B.C. and Wise, Sr., J.P. DNA Microarray and Its Data Analysis. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 37, 2006.

Stackpole, M.M., Wise, S.S., Duzevik, E.G., Munroe, R.C. and Wise, Sr., J.P. Homologous Recombination Repair Protects against Chromate-Induced Chromosome Instability. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 56, 2006.

Savery, L.C., Wise, S.S. and Wise, Sr., J.P. The Role of the Fancg Gene in Protecting Cells from Particulate Chromate-Induced Chromosome Instability. Proceedings of University of Southern Maine’s 3^rd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 85, 2006.

Wise, Sr., J.P. “Sperm Whales: Are They Exposed to Dangerous Levels of Metals and Are They Sentinels for Human Health? A Case Study of the Toxic Effects of Chromium”, Voyage of the Odyssey Science Symposium, University of Southern Maine, Portland, Maine, 2005.

Wise, Sr., J.P. “Chronic Exposure to Lead Chromate Causes Centrosome Abnormalities and Aneuploidy in Human Lung Cells”, Workshop on Chromium and Human Health, University of Southern Maine, Portland, Maine, 2005.

Wise, Sr., J.P. “The Toxicology of Hexavalent Chromium in Humans and Marine Mammals”, University of Texas at El Paso, Texas, 2005.

Wise, Sr., J.P. “The Maine Center for Toxicology and Environmental Health”, Meeting of the Corporate Partners of the University of Southern Maine, Portland, Maine, 2005.

Wise, Sr., J.P. “The Toxic Effects of Environmental Contaminants on Steller Sea Lion Cells”, Mystic Aquarium & Institute for Exploration, Mystic, Connecticut, 2005.

Wise, Sr., J.P. “Developing Right Whale Cell Lines to Study the Consequences of Exposure to Environmental Contaminants”, New England Aquarium, Boston, Massachusetts, 2005.

Wise, Sr., J.P. “The Physico-Chemical Mechanisms of Particulate Cr(VI)-Induced Chromosome Damage”, University of New England, Biddeford, Maine, 2005.

Duzevik, E.G., Wise, S.S., Munroe, R.C. and Wise, Sr., J.P. Repair of Chromate-Induced Chromosome Damage Is Mediated by XRCC1. Toxicological Sciences, 84(S-1): 1135, 2005.

Xie, H., Wise, S.S., Holmes, A.L. and Wise, Sr., J.P. Carcinogenic Lead Chromate Induces DNA Double-Strand Breaks and Activates ATM Kinase in Human Lung Cells. Toxicological Sciences, 84(S-1): 1134, 2005.

Holmes, A.L., Sandwick, S.J., Wise, S.S., Gordon, N., Thompson W.D. and Wise, Sr., J.P. Chronic Exposure to Lead Ions from Lead Chromate Interferes with Normal Mitotic Progression. Toxicological Sciences, 84(S-1): 1145, 2005.

Wise, S.S., Moreland, J.A., Wise, Sr., J. P. Depleted Uranium is Genotoxic and Cytotoxic to Human Lung Cells. Toxicological Sciences, 84(S-1): 160, 2005.

Lynch, J.P., Wise, S.S. and Wise, Sr., J.P. Arsenic Induces Chromosomal and Centromeric Abnormalities in Human Lung Cells. Toxicological Sciences, 84(S-1): 145, 2005.

Xie, H., Wise, S.S. and Wise, Sr., J.P. ATM Mediated Repair of Lead Chromate Induced DNA Double-Strand Breaks Prevents Genomic Instability in Human Lung Cells. Proceedings of the Keystone Symposia on DNA Repair, 243, 2005.

Wise, S.S., Holmes, A.L., Sandwick, S.J., Gordon, N., Thompson W.D. and Wise, Sr., J.P. Lead Ions Interfere with Repair of Particulate Chromate-induced Chromosome Aberrations Resulting in Prolonged Chromosome Instability in Human Lung Cells. Proceedings of the American Association for Cancer Research, 46:3043, 2005.

Xie, H., Wise, S.S. and Wise, Sr., J.P. MRE11 Mediated Repair of Lead Chromate Induced DNA Double-Strand Breaks. Proceedings of the American Association for Cancer Research, 46:3064, 2005.

Wise, S.S., Holmes, A.L., Sandwick, S.J. and Wise, Sr., J.P. Chronic Exposure to Lead Chromate Induces Premature Anaphase and Inhibits Repair of Chromosome Damage in Human Lung Cells. Proceeding of the American Thoracic Society, 2: A744, 2005.

Holmes, A.L., Wise, S.S., Morin, A.T., Goertz, C.E.C, Atkinson, S., Dunn, J.L., Gulland, F.M.D. and Wise, Sr., J.P. Sodium Chromate Toxicity in Steller Sea Lion Cells. Proceedings of the Annual Meeting of the North Atlantic Chapter of the Society for Environmental Toxicology and Chemistry, 2005.

Holmes, A.L., Wise, S.S., Sandwick, S.J., Lingle, W.L., Negron, V.C. and Wise, Sr., J.P. Chronic Exposure to Lead Chromate Causes Centrosome Abnormalities and Aneuploidy in Human Lung Cells. Proceedings of the Biennial Meeting of the Chromium and Human Health Workshop, 2005.

Wise, S.S., Holmes, A.L., Sandwick, S.J. and Wise, Sr., J.P. Lead Chromate-Induced Centromeric Abnormalities in Human Lung Cells. Proceedings of the Biennial Meeting of the Chromium and Human Health Workshop, 2005.

Xie, H, Wise, S.S., Holmes, A.L. and Wise, Sr., J.P. Mechanisms of Repair of Particulate Cr(VI)-Induced DNA Double Strand Breaks. Proceedings of the Biennial Meeting of the Chromium and Human Health Workshop, 2005.

Duzevik, E.G., Wise, S.S., Munroe, R.C. and Wise, Sr., J.P. Repair of Chromate-Induced Chromosome Damage Is Mediated by XRCC1. Proceedings of the Biennial Meeting of the Chromium and Human Health Workshop, 2005.

Kelly, R., Holmes, A.L., Wise, S.S., Morin, A.T., Goertz, C.E.C., Atkinson, S., Dunn, J.L., Gulland, F.M.D. and Wise, Sr., J.P. Sodium Chromate Toxicity in Steller Sea Lion Cells. Proceedings of the Biennial Meeting of the Chromium and Human Health Workshop, 2005.

Savery, L.C., Wise, S.S. and Wise, Sr., J.P. Particulate Chromate-Induced DNA-DNA Crosslinks Do Not Lead to Chromosome Damage. Proceedings of the Biennial Meeting of the Chromium and Human Health Workshop, 2005.

Godard, C.A.J., Wise, S.S., Kelly, R.S., Goodale, B., Kraus, S., Romano, T., O’Hara, T. and Wise, Sr., J.P. Benzo[a]pyrene Cytotoxicity in Right Whale (Eubalaena Glacialis) Skin, Testis and Lung Cell Lines. Proceedings of the Biennial Meeting of PRIMO (Pollution Research in Marine Organisms), 2005.

Wise, S.S., Morin, A.T., Goertz, C.E.C., Dunn, J.L., Gulland, F.M.D., Bozza, M., Atkinson, S. and Wise, Sr., J.P. Metal Toxicity of Sodium Chromate in Steller Sea Lion Bronchus and Dermis Compared To Humans. Proceedings of the Biennial Meeting of PRIMO (Pollution Research in Marine Organisms), 2005.

Wise, S.S., Stackpole, M.M., Camrye, E., Duzevik, E.G. and Wise, Sr., J.P. Non-Homologous End Joining and Homologous Recombination Repair Protect Against Particulate Chromate-Induced Chromosome Instability. Proceedings of the International Conference on Environmental Mutagens and the Annual Meeting of the Environmental Mutagenesis Society, Mutation Research, 577 (1-2): 413, 2005.

Kelly, R.S., Wise, S.S., Kraus, S., Romano, T., O’Hara, T. and Wise, Sr., J.P. Establishment and Immortalization of Whale Cell Lines. Proceedings of the North Atlantic Right Whale Consortium, 2005.
Wise, S.S., Kelly, R.S., Kraus, S., O’Hara, T., Romano, T. and Wise, Sr., J.P. Tributyltin and Hexavalent Chromium Are Cytotoxic and Genotoxic to the North Atlantic Right Whale (Eubalaena glacialis). Proceedings of the North Atlantic Right Whale Consortium, 2005.

Godard, C.A.J., Wise, S.S., Kelly, R.S., Goodale, B., Kraus, S., Romano, T., O’Hara, T. and Wise, Sr., J.P. The Cytotoxicity of Benzo[a]pyrene in Reproductive and Somatic Cells from the Northern Right Whale (Eubalaena glacialis). Proceedings of the Annual Meeting of the North Atlantic Right Whale Consortium, 2005.

Wise, S.S., Kelly, R.S., Kirstein, D.P., Romano, T. and Wise, Sr., J.P. The National Marine Cell Line Library Repository. Proceedings of the International Environmental Specimen Bank Symposium, 2005.

Godard, C.A.J., Wise, S.S., Kelly, R.S., Goodale, B., Kraus, S., Romano, T., O’Hara, T. and Wise, Sr., J.P. Clonogenic Toxicity of Benzo[a]pyrene Is Higher in Reproductive Tissue than in Somatic Tissues of the North Atlantic Right Whale (Eubalaena glacialis). Proceedings of the 16th Biennial Conference of the Biology of Marine Mammals, 107, 2005.

Hu, C., Wise, S., Trites, A., Wise, J. and Kitts, D.D. Vitamin E Protects Steller Sea Lion Cells from Reactive Oxygen Radical Induced Damage. Proceedings of the 16th Biennial Conference of the Biology of Marine Mammals, 132, 2005.

Wise, S.S., Kelly, R.S., Kraus, S., O’Hara, T., Romano, T. and Wise, Sr., J.P. The Effect of Environmental Contaminants; Chromium, Mercury and Tributyltin, on Bowhead and Northern Atlantic Right Whale Cells. Proceedings of the 16th Biennial Conference of the Biology of Marine Mammals, 306, 2005.

Lynch, J.P. and Wise, Sr., J.P. Arsenic Induces Chromosomal and Centromeric Abnormalities in Human Lung Cells. Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 1, 2005.

Goodale, B., Godard, C., Frechette, D. and Wise, Sr., J.P. Cloning of Cytochrome P4501A2 in Marine Mammals. Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 9, 2005.

Sandwick, S., Holmes, A.L., Wise, S.S. and Wise, Sr., J.P. Comparison of Human and Bowhead Lung Cells through Cytotoxicity, Metal Ion Uptake and Clastogenicity. Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 11, 2005.

Throckmorton, H., Wise, S.S. and Wise, Sr., J.P. Comparison of Mercury on Human and Bowhead Whale Lung Cells. Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 12, 2005.

Chen, T., Wise, S.S. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Mercury and TBT in the Northern Atlantic Right Whale. Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 18, 2005.

Stackpole, M.M., Wise, S.S., Duzevik, E.G., Munroe, R.C. and Wise, Sr., J.P. Homologous Recombination Repair Protects against Chromate-Induced Chromosome Instability. Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 44, 2005.

Grau, M., Wise, S.S. and Wise, Sr., J.P. Interindividual Differences in the Effects of Chromium on the North Atlantic Right Whale (Eubalaena glacialis). Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 54, 2005.

Camrye, E.A., Wise, S.S. and Wise, Sr., J.P. Role of Ku in NHEJ Repair of Particulate and Soluble-Induced Double Strand Breaks and Chromosome Damage. Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 77, 2005.

Savery, L.C., Wise, S.S. and Wise, Sr., J.P. Role of the Fanc-g Genes in Repair of Particulate Chromium Induced DNA-DNA Crosslinks and Chromosome Damage. Proceedings of University of Southern Maine’s 2^nd Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 78, 2005.

Wise, Sr., J.P. “The Physico-Chemical Mechanisms of Particulate Cr(VI)-Induced Genotoxicity”, University of Vermont, Burlington, Vermont, 2004.

Wise, Sr., J.P. “Mechanisms of Arsenic-Induced Human Lung and Bladder Cancer”, Maine Cancer Foundation, Portland, Maine, 2004.

Wise, Sr., J.P. “Mechanisms of Particulate Chromate-Induced Genotoxicity “, Third Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis. National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia, 2004.

Wise, Sr., J.P. “The Future of Environmental Research”, Osher Lifelong Learning Institute (OLLI), Portland, Maine, 2004.

Wise, Sr., J.P. “Toxicology of Hexavalent Chromium in Human Lung Cells”, Maine Medical Center, Portland, Maine, 2004.

Wise, Sr., J.P. “Developing a Nationally Recognized Program in Environmental Toxicology”, Annual Meeting of the Alumni Association of the University of Southern Maine, Portland, Maine, 2004.

Diaz, W.C., Wise, S.S. and Wise, Sr., J.P. The Cytotoxicity of Depleted Uranium in Human Bronchial Cells. Proceedings of the Annual Meeting of the New England Chapter of New England Pharmacologists, 2004.

Morin, A.T., Goertz, C.E.C., Wise, S.S., Dunn, J.L., Gulland, F, Jayasundara, N., Bozza, M., Atkinson, S. and Wise, Sr., J.P. Comparative Cytotoxicity of Hexavalent Chromium Compounds in Humans and Steller Sea Lions. Proceedings of the Annual Meeting of the New England Chapter of New England Pharmacologists, 2004.

Holmes, A.L., Gordon, N. and Wise, Sr., J.P. Chromium Ions Are the Proximate Clastogenic Species for Particulate Hexavalent Chromium in Human Lung Cells. Proceedings of the Annual Meeting of the New England Chapter of New England Pharmacologists, 2004.

Xie, H, Wise, S.S., Holmes, A, Ketterer, M.E., Hartsock, W.J. and Wise, Sr., J.P. Particle Dissolution Is Necessary for Lead Chromate-Induced Genotoxicity in Human Bronchial Cells. Proceedings of the Annual Meeting of the New England Chapter of New England Pharmacologists, 2004.

Wise, S.S., Holmes, A.L., Xie, H. and Wise, Sr., J.P. The Physico-Chemical Mechanisms of Particulate Chromium (VI)-Induced Clastogenesis. Proceedings of the AACR Special Conference in Radiation Biology and Cancer, 2004.

Holmes, A.L., Gordon, N. and Wise, Sr., J.P. Lead Chromate-Induced Cytotoxicity in Human Bronchial Cells is Mediated by Extracellular Chromium. Toxicological Sciences 67(S): 760, 2004.

Morin, A.T., Goertz, C.E.C., Wise, S.S., Dunn, J.L., Gulland, F, Jayasundara, N., Bozza, M., Atkinson, S. and Wise, Sr., J.P. Sodium Chromate Toxicity in Bronchus and Dermis of Steller Sea Lions and Humans. Toxicological Sciences, 67(S): 757, 2004.

Diaz, W.C., Wise, S.S. and Wise, Sr., J.P. Uranium is Cytotoxic and Genotoxic to Human Lung Cells. Toxicological Sciences, 67(S): 272, 2004.

Goertz, C.E.C., Wise, S.S., Dunn, J.L., Gulland, F, Morin, A., Jayasundara, N., Bozza, M., Atkinson, S. and Wise, Sr., J.P. Cytotoxicity of Two Heavy Metals in Steller Sea Lion Dermal, Renal, Bronchial and Testicular Cells. Toxicological Sciences, 67(S): 756, 2004.

Moreland, J.A., Teufack, S., Sandwick, S., Dufour, J-F., Wise, S.S., Holmes, A.L., Ketterer, M.E., Hartsock, W.J., Fomchenko, E., Katsifis, S.P. and Wise, Sr., J.P. Lead Chromate (LC) Induces Cell Cycle Arrest in WTHBF-6 Cells, However Lead Alone Is Mitogenic. Toxicological Sciences, 67(S): 270, 2004.

Wise, S.S., Holmes, A.L., Thompson, M., Smith, B.E., O’Hara, T. and Wise, Sr., J.P. Comparative Chromium Toxicity in Cultured Bowhead Whale and Human Lung Cells. Toxicological Sciences, 67(S): 759, 2004.

Xie, H., Holmes, A.L., Wise, S.S., Gordon, N. and Wise, Sr., J.P. Particulate Hexavalent Chromium-Induced Clastogenesis is Mediated by Extracellular Dissolution that Does Not Require Particle Cell Contact. Toxicological Sciences, 67(S): 281, 2004.

Jalbert, A., Gordon, N., Langley-Turnbaugh, S. and Wise, Sr., J.P. The Effect of Urban Particulate Matter on Human Lung Cells Toxicological Sciences, 67(S): 1039, 2004.

Zhang, Y, Wise, Sr., J.P., Holford, T.R., Xie, H., Boyle, P., Zahm, S.H., Zhang B., Zou, K.Y., Owens, P.H. and Zheng, T. Polychlorinated Biphenyls, Cytochrome P4501A1 Polymorphism and Risk of Breast Cancer in Connecticut Women. Proceedings of the American Association for Cancer Research, 45: 3729, 2004.

Wise, S.S., Holmes, A.L., Xie, H., Gordon, N., Thompson W.D. and Wise, Sr., J.P. Lead Chromate-Induced Cytotoxicity In Human Bronchial Cells Is Mediated By Extracellular Chromium and Does Not Require Functional p53 or Rb. Proceedings of the American Association for Cancer Research, 45: LB-180, 2004.

Xie, H., Moreland, J.A., Wise, S.S. and Wise, Sr., J.P. Particulate Hexavalent Chromium Induces DNA Double Strand Breaks in Human Bronchial Cells. Proceedings of the American Association for Cancer Research, 45: LB-168, 2004.

Goertz, C.E.C., Wise, S.S., Dunn, J.L., Bozza, M., Atkinson, S., Gulland, F.M.D., Taylor, R.J. and Wise, Sr., J.P. In Vitro Metal Toxicity in Steller Sea Lion (Eumetopias jubatus) Fibroblasts with an Emphasis on Hexavalent Chromium. Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 35: 74-75 2004.

Wise, S.S., Holmes, A.L., Xie, H., Gordon, N., Moreland, J.A., Sandwick, S.J., Stackpole, M.M., Fomchenko, E., Teufack, S., May, Jr., A.J., Katsifis, S.P., Thompson, W.D. and Wise, Sr., J.P. Mechanisms of Particulate Chromate-Induced Genotoxicity. Proceedings of the 3^rd Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, 2004.

Xie, H., Wise, S.S., Holmes, A.L. and Wise, Sr., J.P. Carcinogenic Lead Chromate Induces Double-Strand Breaks in Human Lung Cells. Proceedings of the 3^rd Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, 2004.

Goertz, C.E.C., Wise, S.S., Dunn, J.L., Gulland, F.M.D., Morin, A., Jayasundra, N., Bozza, M., Atkinson, S. and Wise, Sr., J.P. Sodium Chromate Toxicity and Uptake in Steller Sea Lion Cells. Proceedings of the 22^nd Wakefield Fisheries Symposium: Sea Lions of the World Conservation and Research in the 21^st Century, 2004.

Lynch, J.P., Wise, S.S. and Wise, Sr., J.P. Arsenic Induces Centromeric Abnormalities and Endoreduplication in Chromosomes of Human Lung Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 2004.

Chason, J., Bodoky, A., Xie, H., Wise, S.S., Holmes, A.L., Teufack, S., Katsifis, S. and Wise, Sr., J.P. The Functional Role of NBS1 in the Repair of Cr(VI)-Induced DNA Damage. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 2004.

Stackpole, M.M., Wise, S.S., Duzevik, E.G., Munroe, R.C., Thompson, L.H. and Wise, Sr., J.P. Particulate Chromate-Induced Genomic Instability Is Prevented by Homologous Recombination. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 2004.

 Duzevik, E.G., Munroe, R.C., Wise, S.S. and Wise, Sr., J.P. XRCC1 Is Involved in Repair of Lead Chromate-Induced Chromosome Damage. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 2004.

Sandwick, S.J., Holmes, A.L., Wise, S.S., Gordon, N. and Wise, Sr., J.P. Lead Ions Disrupt Normal Mitotic Progression in Human Lung Cells after More Chronic Exposures to Lead Chromate. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 2004.

Xie, H., Wise, S.S. and Wise, Sr., J.P. Carcinogenic Lead Chromate Induces DNA Double-Strand Breaks in Human Lung Cells. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 2004.

Van Epps, G., Jalbert, A., Alley, D., Langley-Turnbaugh, S., Gordon, N.R. and Wise, J.P. Metal Composition of Maine Particulate Matter (PM) and Effects of These Metals on Human Lung Fibroblasts. Proceedings of the Annual Meeting of the Northeast Chapter of the Society of Toxicology, 2004.

Kelly, R., Wise, S.S., Kraus, S., O’Hara, T., Romano, T. and Wise, Sr., J.P. Development of Right Whale and Bowhead Whale Cell Lines. Proceedings of the Annual Meeting of the North Atlantic Right Whale Consortium, 2004.

Wise, S.S., Kelly, R., Kraus, S., O’Hara, T., Romano, T. and Wise, Sr., J.P. The Effect of Environmental Contaminants on Northern Atlantic Right Whale and Bowhead Whale Cell Cultures. Proceedings of the Annual Meeting of the North Atlantic Right Whale Consortium, 2004.

Bank, M.S., Driscoll, C., Fernandez, I., Wise, J., Amirbahman, A. and Foster, D. Effects of Disturbance Regimes on Mercury Bioaccumulation in Two-Lined Salamanders from Stream Ecosystems in the Northeastern United States. Proceedings of the Annual Meeting of the Northeast Resource Council, 2004.

Wise, S.S., Stackpole, M.M., Duzevik, E.G., Munroe, R.C., Thompson, L.H. and Wise, Sr., J.P. Homologous Recombination Protects against Particulate Chromate-Induced Genomic Instability in Chinese Hamster Cells. Proceedings of the ASM Special Conference: DNA Repair and Mutagenesis: from Molecular Structure to Biological Consequences, 2004.

 Van Epps, G., Langley-Turnbaugh, S., Gordon, N.R. and Wise, J.P. The Relationship between Maine Soil and PM10. Proceedings of the International Soil Science Meeting, December 2004.

Goertz, C.E.C., Wise, S.S., Dunn, J.L., Gulland, F, Morin, A., Jayasundara, N., Bozza, M., Atkinson, S. and Wise, Sr., J.P. Cytotoxicity of Two Heavy Metals in Steller Sea Lion Dermal, Renal, Bronchial and Testicular Cells. Proceedings of University of Southern Maine’s 1^st Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 17, 2004.

Morin, A.T., Goertz, C.E.C., Wise, S.S., Dunn, J.L., Gulland, F, Jayasundara, N., Bozza, M., Atkinson, S. and Wise, Sr., J.P. Metal Toxicity of Sodium Chromate in Steller Sea Lion Bronchus and Dermis Compared to Humans. Proceedings of University of Southern Maine’s 1^st Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 17, 2004.

Sandwick, S., Wise, S.S., Holmes, A.L. and Wise, Sr., J.P. The Effect of Exposure Time on Lead Chromate-Induced Cytotoxicity in Human Lung Cells. Proceedings of University of Southern Maine’s 1^st Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 20, 2004.

Lynch, J.P. and Wise, Sr., J.P. Effects of Arsenic on Chromosomes with Time after Exposure. Proceedings of University of Southern Maine’s 1^st Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 23, 2004.

Holmes, A.L., Gordon, N. and Wise, Sr., J.P. Lead Chromate-induced Cytotoxicity in Human Bronchial Cells is Mediated by Extracellular Chromium. Proceedings of University of Southern Maine’s 1^st Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 44, 2004.

Moreland, J.A., Teufack, S., Sandwick, S., Dufour, J-F., Wise, S.S., Holmes, A.L., Ketterer, M.E., Hartsock, W.J., Fomchenko, E., Katsifis, S.P. and Wise, Sr., J.P. Lead is Mitogenic to WTHBF-6 cells, but Lead Chromate (LC) Induces Cell Cycle Arrest. Proceedings of University of Southern Maine’s 1^st Annual Thinking Matters Conference: USM Research, Scholarship and Creativity Symposium, 45, 2004.

Wise, Sr., J.P. “Comparative Chemical Carcinogenesis of Environmental Contaminants in Balaenidae Whales (Balaena mysticetus and Eubalaena glacialis) and Humans: Bowhead Whales Are Resistant to Hexavalent Chromium”, Aquatic Animal Models of Human Disease Conference, Reston, Virginia, 2003.

Wise, Sr., J.P. “Application of Cell Culture Studies in Environmental Toxicology and the Development of the Center for Integrated and Applied Environmental Toxicology at the University of Southern Maine”, 30^th Anniversary of the Maine Biological and Biomedical Sciences Society, Bar Harbor, Maine, 2003.

Wise, Sr., J.P., Holmes, A. L., Wise, S.S., Little, J.A., Xie, H., Bozza, M., Moreland, St. Aubin, D.J., J.A., Dunn, J.L., Atkinson, S., Gulland, F. and Bursian, S. Hexavalent Chromium Cytotoxicity Is Organ and Species Specific for Steller Sea Lion and Mink Cells. Proceedings of the EVOS-GEMS/GLOBE /NMFS Steller Sea Lion Research Symposium, 2003.

Holmes, A.L., Wise, S.S., Ketterer, M.E., Xie, H., Hartsock, W., Shuler, J., Katsifis, S. and Wise, Sr., J.P. Comparative Genotoxicity of Two Particulate Hexavalent Chromium Compounds in Human Bronchial Cells. Toxicological Sciences, 72(S): 218, 2003.

Wise, S.S., Holmes, A, Ketterer, M.E., Hartsock, W.J., Fomchenko, E., Katsifis, S. and Wise, Sr., J.P. Chromium Is the Proximate Genotoxic Species in Lead Chromate-Induced Clastogenicity in Human Bronchial Cells. Toxicological Sciences, 72(S): 217, 2003.

Shuler, J.H.C., Wise, S.S., Katsifis, S. and Wise, Sr., J.P. Barium Chromate is Cytotoxic and Clastogenic to Human Bronchial Cells. Toxicological Sciences, 72(S): 218, 2003.

Moreland, J.A., Wise, S.S., Holmes, A.L., Ketterer, M.E., Hartsock, W.J., Thomas, R.A., Fomchenko, E., Katsifis, S.P. and Wise, Sr., J.P. The Phase of Lead Chromate Induced Cell Cycle Arrest Is Concentration Dependent. Toxicological Sciences, 72(S): 218, 2003.

Little, J.E., Wise, S.S., Slotnick, M.J and Wise, Sr., J.P. Cytotoxicity and Clastogenicity of Arsenic, Cadmium and Chromium in Human Bronchial Cells. Toxicological Sciences, 72(S): 219, 2003.

Xie, H, Wise, S.S., Holmes, A, Ketterer, M.E., Hartsock, W.J. and Wise, Sr., J.P. Lead Chromate Genotoxicity Is Mediated by Particle Dissolution and Not Particle Internalization. Toxicological Sciences, 72(S): 217, 2003.

Goertz, C.E.C., Wise, S.S., Dunn, J.L. and Wise, Sr., J.P. Cell Culture, Toxicology and Stranded Marine Mammals Proceedings of the Maine Biotechnology Association Annual Meeting, 2003.

Moreland, J.A., Wise, S.S., Holmes, A.L., Ketterer, M.E., Hartsock, W.J., Thomas, R.A., Fomchenko, E., Katsifis, S.P. and Wise, Sr., J.P. The Phase of Lead Chromate Induced Cell Cycle Arrest Is Concentration Dependent. Proceedings of the Maine Biotechnology Association Annual Meeting, 2003.

Goertz, C.E.C., Wise, S.S., Dunn, J.L. and Wise, Sr., J.P. Cell Culture, Toxicology and Stranded Marine Mammals. Proceedings of the Northeast Region Stranding Network, 2003.

Lynch, J.P., Little, J.E., Wise, S.S., Slotnick, M.J. and Wise, Sr., J.P. Comparative Genotoxicity of Arsenic, Cadmium and Chromium in Human Bronchial Cells. Proceedings of the Maine Biological and Medical Sciences Annual Symposium, 2003.

Xie, H., Wise, S.S., Holmes, A.L, Ketterer, M.E., Hartsock, W.J. and Wise, Sr., J.P. Particle Dissolution Is Necessary for Lead Chromate-Induced Genotoxicity in Human Bronchial Cells. Proceedings of the Maine Biological and Medical Sciences Annual Symposium, 2003.

Holmes, A.L., Goertz, C.E.C., Wise, S.S., Little, J.E., Moreland, J.A., Bozza, M., St. Aubin, D.K., Dunn, J.L., Atkinson, S., Gulland, F. and Wise, Sr., J.P. Cell Culture and Toxicology of Marine Mammals. Proceedings of the Maine Biological and Medical Sciences Annual Symposium, 2003.

Wise, S.S., Goertz, C.E.C., Little, J.E., Bozza, M., St. Aubin, D.K., Dunn, J.L., Atkinson, S., Gulland, F and Wise, Sr., J.P. Metal Toxicity in Cultured Steller Sea Lion Fibroblasts. Proceedings of the Annual Meeting of the International Association of Aquatic Animal Medicine, 35: 140, 2003.

Wise, Sr., J.P., Wise, S.S., Goertz, C.E.C., Thompson, M., Smith, B., O’Hara, T., St. Aubin, D.K. and Dunn, J.L. Comparative Chemical Carcinogenesis of Environmental Contaminants in Balaenidae Whales (Balaena mysticetus and Eubalaena glacialis) and Humans: Bowhead Whales Are Resistant to Hexavalent Chromium. Proceedings of the Aquatic Animal Models of Human Disease Conference, 30, 2003.

Morin, A.T., Goertz, C.E.C., Wise, S.S., Dunn, J.L., Gulland, F., Jayasundara, N., Bozza, M, Atkinson, S. and Wise, Sr., J.P. Comparative Cytotoxicity of Hexavalent Chromium in Humans and Steller Sea Lions. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2003.

Diaz, W.C., Wise, S.S. and Wise, Sr., J.P. The Cytotoxicity and Clastogenicity of Depleted Uranium in Human Bronchial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2003.

Goertz, C.E.C., Wise, S.S., Dunn, J.L., Gulland, F., Morin, A.T., Jayasundara, N., Bozza, M., Atkinson, S. and Wise, Sr., J.P. Sodium Chromate and Cadmium Chloride Toxicity in Steller Sea Lion Dermal, Renal, Bronchial and Testicular Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2003.

Moreland, J.A., Teufack, S., Sandwick, S., Dufour, J-F., Wise, S.S., Holmes, A.L., Ketterer, M.E., Hartsock, W.J., Fomchenko, E., Katsifis, S.P. and Wise, Sr., J.P. Particulate Hexavalent Chromium-Induced Cell Cycle Arrest Is Mediated by Cr Ions. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2003.

Wise, S.S., Holmes, A.L., Thompson, M., Smith, B.E., O’Hara, T. and Wise, Sr., J.P. Cytotoxicity of Particulate and Soluble Hexavalent Chromium in Bowhead Whale and Human Bronchial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2003.

Xie, H., Holmes, A.L., Wise, S.S., Gordon, N. and Wise, Sr., J.P. Lead Chromate Releases Extracellular Cr Ions That Produce Its Clastogenic Effects. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2003.

Wise, Sr., J.P., Wise, S.S., Goertz, C.E.C., Bozza, M., St. Aubin, D.K., Dunn, J.L., Atkinson, S. and Gulland, F. Toxicity of Heavy Metals in Cultured Steller Sea Lion Cells. Proceedings of the Society of Environmental Toxicology and Chemistry, 2003.

Goertz, C.E.C., Wise, S.S., Jayasundara, N., St. Aubin, D.K., Dunn, J.L., Bozza, M., Atkinson, S., Gulland, F. and Wise, Sr., J.P. Metal Toxicity in Cultured Steller Sea Lion Fibroblasts. Proceedings of the Annual Meeting of the Society of Marine Mammalogy, December 2003.

Wise, S.S., Goertz, C.E.C., Thompson, M., Smith, B., O’Hara, T., St. Aubin, D.K. and Dunn, J.L. and Wise, Sr., J.P. The Effects of Environmental Contaminants on Balaenidae Whales (Balaena mysticetus and Eubalaena glacialis): Metal Toxicity in Bowhead Whales. Proceedings of the Annual Meeting of the Society of Marine Mammalogy, December 2003.

Wise, S.S., Holmes, A., Ketterer, M.E., Hartsock, W.J., Fomchenko, E., Katsifis, S. and Wise, Sr., J.P. Chromium Is the Proximate Genotoxic Species in Lead Chromate-Induced Clastogenicity in Human Bronchial Cells. Presented at the University of Southern Maine’s Annual Scholarship and Creativity Fair, 2003.

Holmes, A.L, Wise, S.S., Ketterer, ME, Xie, H, Hartsock, W, Shuler, J., Katsifis, S. and Wise, Sr., J.P. Comparative Genotoxicity of Two Particulate Hexavalent Chromium Compounds in Human Bronchial Cells. Presented at the University of Southern Maine’s Annual Scholarship and Creativity Fair, 2003.

Whitney, D., Wise, S.S. and Wise, Sr., J.P. Cytotoxicity of Soluble Hexavalent Chromium in Human Lung Cells under Hypoxic Conditions. Presented at the University of Southern Maine’s Annual Scholarship and Creativity Fair, 2003.

Lynch, J.P., Little, J.E., Wise, S.S., Slotnick, M.J and Wise, Sr., J.P. Comparative Genotoxicity of Arsenic, Cadmium and Chromium in Human Bronchial Cells Presented at the University of Southern Maine’s Annual Scholarship and Creativity Fair, 2003.

Goertz, C.E.C., Wise, S.S., Holmes, A.L., Little, J.E., Moreland, J.A., Bozza, M., St. Aubin, D.K., Dunn, J.L., Atkinson, S., Gulland, F. and Wise, Sr., J.P. Cell Culture and Toxicology of Marine Mammals. Presented at the University of Southern Maine’s Annual Scholarship and Creativity Fair, 2003.

Moreland, J.A., Wise, S.S., Holmes, A.L., Ketterer, M.E., Hartsock, W.J., Thomas, R.A., Fomchenko, E., Katsifis, S.P. and Wise, Sr., J.P. The Phase of Lead Chromate Induced Cell Cycle Arrest Is Concentration Dependent. Presented at the University of Southern Maine’s Annual Scholarship and Creativity Fair, 2003.

Xie, H., Wise, S.S., Holmes, A.L, Ketterer, M.E., Hartsock, W.J. and Wise, Sr., J.P. Particle Dissolution Is Necessary for Lead Chromate-Induced Genotoxicity in Human Bronchial Cells. Presented at the University of Southern Maine’s Annual Scholarship and Creativity Fair, 2003.

Wise, Sr., J.P. “Establishing a Center for Integrated and Applied Environmental Toxicology at the University of Southern Maine”, Annual Meeting of the Biotechnology Association of Maine, Portland, Maine, 2002.

Wise, Sr., J.P. “Establishing A New Human Lung Cell Culture Model for Studying Carcinogenic Metals”, Second Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia, 2002.

Wise, Sr., J.P. “A Human Lung Cell Culture Model for Studying Carcinogenic Metals”, Department of Pathobiology, University of Connecticut, Storrs, Connecticut, 2002.

Wise, Sr., J.P. “A New Human Lung Cell Culture Model for Studying Particulate Metal Compounds”, Department of Chemical Engineering, Yale University, New Haven, Connecticut, 2002.

Bidulescu, A., Wise, S.S., May, A., Tang, E.R., Bryant, B.H., Schumm, K.R. and Wise, Sr., J.P. Hexavalent Chromium Toxicity in Human Lung Cells, Chinese Hamster Ovary Cells and A549 Cells: Current Cell Culture Models Are Inadequate. Toxicological Sciences, 66(S): 32 (150), 2002.

Wise, S.S., Elmore, L.W., Antonucci, P.G., Holt, S.E., Bryant, B.H. and Wise, Sr., J. P. A New Human Bronchial Cell Culture Model for Investigating Metal-Induced Lung Carcinogenesis. Toxicological Sciences, 66(S): 32 (151), 2002.

Antonucci, P.G., Wise, S.S., Pincavage, A., Singh, N.P. and Wise, Sr., J.P. Cytotoxicity and Genotoxicity of Cr(VI) in Human Bronchial Cells. Toxicological Sciences 66(S): 32 (152), 2002.

Little, J.E., Wise, S.S. and Wise, Sr., J.P. The Genotoxicity of Particulate and Soluble Hexavalent Chromium in Human Bronchial Cells. Toxicological Sciences, 66(S): 32 (LB16), 2002.

Barnes, D.W., Forrest Jr., J.N., Wise, Sr., J.P. and Winn, R.N. Derivation of Continuous Marine Cell Lines for Model Systems in Toxicology and Cell Biology The Bulletin, Mount Desert Island Biological Laboratory, 41: 45-47, 2002.

Wise, Sr., J.P., Antonucci, P.G., Holt, S.E., Elmore, L.W., Forrest Jr., J.N., Boyer, J. and Bryant, B.H. Establishing Cell Lines In Four Marine Species: Bowhead Whale, (Balaena mysticetus), Beluga Whale (Delphinapterus leucas), Little Skate (Raja erinacea) and Spiny Dogfish (Squalus acanthias). The Bulletin, Mount Desert Island Biological Laboratory, 41: 48-49, 2002.

Wise, S.S., Elmore, L.W., Antonucci, P.G., Holt, S.E., Little, J.E., Bryant, B.H. and Wise, Sr., J. P. Establishing a New Lung Cell Culture Model for Studying Carcinogenic Metals. Proceedings of the 2nd Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis, 2002.

Holmes, A.L., Wise, S.S., Ketterer, M.E., Xie, H., Hartsock, W.J., Shuler, J.H.C., Katsifis, S.P. and Wise, Sr., J.P. Barium Chromate Is More Potent Than Lead Chromate in Human Bronchial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2002.

Shuler, J.H.C., Wise, S.S., Katsifis, S.P. and Wise, Sr., J.P. The Cytotoxicity and Clastogenicity of Barium Chromate in Human Bronchial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2002.

Moreland, J.A., Wise, S.S., Holmes, A.L., Ketterer, M.E., Hartsock, W.J., Thomas, R.A., Fomchenko, E., Katsifis, S.P. and Wise, Sr., J.P. Lead Chromate-Induced Cell Cycle Arrest Progresses From G1 to S-Phase Arrest With Increasing Concentrations. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2002.

Lynch, J.P., Little, J.E., Wise, S.S., Slotnick, M.J and Wise, Sr., J.P. Comparative Genotoxicity of Arsenic, Cadmium and Chromium in Human Bronchial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2002.

Xie, H., Wise, S.S., Holmes, A.L, Ketterer, M.E., Hartsock, W.J. and Wise, Sr., J.P. Particle Dissolution Is Necessary For Lead Chromate-Induced Genotoxicity in Human Bronchial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2002.

Wise, S.S., Holmes, A.L., Ketterer, M.E., Hartsock, W.J., Fomchenko, E., Katsifis, S.P. and Wise, Sr., J.P. Lead Chromate-Induced Genotoxicity Is Mediated by Chromium and Not Lead in Human Bronchial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2002.

Wise, S.S., Elmore, L.W., Holt, S.E., Little, J.E., Bryant, B.H. and Wise, Sr., J. P. Ectopic Expression of hTERT in Human Bronchial Cells Extends Cellular Lifespan without Affecting Hexavalent Chromium-Induced Cytotoxicity or Genotoxicity. Proceedings of the American Association for Cancer Research Conference on the Role of Telomeres and Telomerase in Cancer, 2002.

Wise, Sr., J.P. “Establishing a New Human Lung Cell Culture Model to Study Chromium-Induced Genotoxicity”, University of Southern Maine, Portland Maine, 2001

Wise, Sr., J.P. “Toxicology of Chromium in Marine Animals”, Mount Desert Island Biological Laboratory, Salisbury Cove, Maine, 2001.

Wise, Sr., J.P. “Establishing a New Cell Culture Model of Human Bronchial Cells”, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, 2001.

Wise, Sr., J.P. “Using Telomerase to Immortalize Cells”, Yale Cancer Center, Yale University, New Haven, Connecticut, 2001.

Wise, S.S., Ketterer, M.E., Antonucci, P. G. and Wise, Sr., J.P. Genotoxic Effects of Particulate and Soluble Cr(VI) in a Human Bronchial Cell Culture Model. Environ Mol Mutagen, 37: 80, 2001.

Wise, Sr., J.P., Wise, S.S., Elmore, L.W., Antonucci, P.G. and Holt, S.E. Establishing Continuous Human Cell Lines with hTERT. Proceedings of the Mount Desert Island Biological Laboratory Meeting on Marine Models, 2001.

Wise, Sr., J.P., Wise, S.S. and St. Aubin, D.J. Establishing Continuous Cell Lines in Three Marine Species Delphinus delphius, Tursiops truncatus and Delphinapterus leucas. Proceedings of the Mount Desert Island Biological Laboratory Meeting on Marine Models, 2001.

Wise, Sr., J.P., Wise, S.S. and St. Aubin, D.J. Establishing Cultures of Bronchial Cells from the Common Dolphin (Delphinus delphis). Society of Environmental Toxicology and Chemistry (SETAC) Abstracts, 158, 2001.

Bidulescu, A, Wise, S.S., May, A., Tang, E.R., Bryant, B.H., Schumm, K.R. and Wise, Sr., J.P. A Comparison of Chromium Toxicity in Three Cell Culture Models. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2001.

Wise, S.S. and Wise, Sr., J.P. The Cytotoxicity and Clastogenicity of Particulate and Soluble Hexavalent Chromium in Human Bronchial Cells. Proceedings of the Northeast Society of Toxicology (NESOT) Annual Meeting, 2001.

Wise, Sr., J.P., Antonucci, P.G. and Bryant, B.H. Toxicology of Hexavalent Chromium in Five Marine Animals: Bowhead Whale, (Balaena mysticetus), Beluga Whale (Delphinapterus leucas), Little Skate (Raja erinacea), Spiny Dogfish (Squalus acanthias) and the Killifish (Fundulus heteroclitus). The Bulletin, Mount Desert Island Biological Laboratory, 40: 29-30, 2001.

Wise, Sr., J.P., Public Presentation on Metal Toxicology in Whales, Mount Desert Island Biological Laboratory, Salisbury Cove, Maine, 2000.

Wise, Sr., J.P. “Chromium and Cancer in Humans and Marine Animals”, Southern California Chapter of the Society of Toxicology, San Diego, California, 2000.

Wise, Sr., J.P. “Comparative Toxicology of Metals in Humans and Marine Animals”, Mount Desert Island Biological Laboratory, Salisbury Cove, Maine, 2000.

Rabinowitz, P.M., Wise, Sr., J.P., Antonucci, P.G. and Mobo, B.H. Glutathione-S-Transferase M1 (GSTM1) and T1 (GSTT1) as Predictors of Susceptibility to High Frequency Hearing Changes in Noise-Exposed Workers. Proceedings of the Environmental Carcinogenesis Population Risk and Genetic Susceptibility Meeting, 2000.

Wise, S.S., Elmore, L.W., Antonucci, P.G., Holt, S.E., Bryant, B.H. and Wise, Sr., J. P. A Human Bronchial Cell Model for Lung Carcinogens. Proceedings of the Northeast Society of Toxicology Meeting, 2000.

Wise, S.S., Elmore, L.W., Antonucci, P.G., Holt, S.E., Bryant, B.H. and Wise, Sr., J. P. Establishing a Human Bronchial Cell Culture Model for Lung Carcinogens. Proceedings of the American College of Toxicology Annual Meeting, 2000.

1990-1999

Wise, Sr., J.P. “Chromium-induced Carcinogenesis”, University of Connecticut at Farmington, Farmington, Connecticut.

May, Jr., A.J., Wise, S.S., Stearns, D.M., Ketterer, M.E. and Wise, Sr., J.P. Particulate Hexavalent Chromium and Human Health in The Arctic. Proceedings of the American Association for the Advancement of Science Meeting, 1999.

May, Jr., A.J., Wise, S.S., Stearns, D.M., Ketterer, M.E. and Wise, Sr., J.P. Differential Effects of Particulate and Soluble Hexavalent Chromium on the Cell Cycle. Proceedings of the American Association for Cancer Research Conference on the Genetic and Functional Consequences of Cell Cycle Alteration in Cancer, 1999.

Wise, Sr., J.P., Caporasso, N.E., Trivers, G.E., Tucker, M.A., Trump, B.F., Harris, C.C. and Shields, P.G. Glutathione-S-Transferase Theta (GST-T) and Lung Cancer Risk. Proceedings of the American Association for Cancer Research Conference on Cancer Susceptibility Genes and Molecular Carcinogenesis Meeting, 1996.

Wise, Sr., J.P., Caporasso, N.E., Trivers, G.E., Tucker, M.A., Trump, B.F., Harris, C.C. and Shields, P.G. The relationship of Glutathione-S-Transferase Theta (GST-T) Polymorphism to Lung Cancer Risk. Proceedings of the American Association for Cancer Research, 37: 1784, 1996.

Hussain, S.P., Amstad, P., Ambs, S., Bennett, W.P., Wise, Sr., J.P., Harrington, A., Shields, P.G. and Harris, C.C. P53 Mutation Load Is Increased in Ulcerative Colitis, a Cancer-Prone Disease. Proceedings of the American Association for Cancer Research, 37: 963, 1996.

Stearns, D.M., Wise, J.P. Sr., Patierno, S.R. and Wetterhahn, K.E. The Dietary Supplement Chromium Picolinate Induces Chromosome Damage in Chinese Hamster Ovary Cells. The FASEB Journal Abstracts, 9(3): A451, 1995.

Blankenship, L.J., Wise, J.P., Orenstein, J.M. and Patierno, S.R. Vitamin Pretreatment Protects Cells from Chromium-Induced Apoptosis without Decreasing Chromium-Induced DNA Adducts. Proceedings of the American Association for Cancer Research, 36: 68, 1995.

Manning, F.C.R., Blankenship, L.J., Wise, J.P., Xu, J., Bridgewater, L.C. and Patierno, S.R. Induction of Apoptosis by Carcinogenic Chromate: Relationship to Genotoxicity, Cell Cycle Delay and Inhibition of Macromolecular Synthesis. Proceedings, Second International Meeting on Molecular Mechanisms of Metal Toxicity and Carcinogenicity, 1993.

Wise, J.P., Orenstein, J.M. and Patierno, S.R. Inhibition of Lead Chromate Clastogenesis by Ascorbate: Relationship to Particle Dissolution and Uptake. Proceedings of the American Association for Cancer Research, 34: 3316, 1993.

Wise, J.P., Xu, J. and Patierno, S.R. Relationship of Chromate-Induced DNA Damage to Chromosomal Aberrations. The Toxicologist, 12: 1201, 1992.

Patierno, S.R., Dirscherl, L. and Wise, J.P. Mitogenesis and Clastogenesis of Particulate Metal Carcinogens in Respiratory Epithelial Cells. The FASEB Journal, Abstracts, 5: 7156, 1991.

Wise, J.P., Leonard, J.C. and Patierno, S.R. Clastogenesis of Lead Chromate (PbCrO₄) Particles in Hamster and Human Cells. Proceedings of the American Association for Cancer Research, 32: 635, 1991.